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anti-MUC16 antibody :: Rabbit anti-Human Mucin-16 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7000331
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mucin-16 (MUC16), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Mucin-16 polyclonal Antibody

 Product Synonym Names    MUC-16; Ovarian cancer-related tumor marker CA125; MUC16; CA125
 Product Gene Name   

anti-MUC16 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606154
 3D Structure    ModBase 3D Structure for Q8WXI7
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Mucin-16 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-33344 / sc-33346
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MUC16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-MUC16 antibody    Cancer
 Applications Tested/Suitable for anti-MUC16 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-MUC16 antibody    Recommended dilution: IHC: 1:20-1:200
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 Immunohistochemistry (IHC) of anti-MUC16 antibody    Immunohistochemistry of paraffin-embedded human prostate using MBS7000331 at dilution of 1:20
anti-MUC16 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-MUC16 antibody    Immunohistochemistry of paraffin-embedded human kidney using MBS7000331 at dilution of 1:20
anti-MUC16 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for MUC16. It may not necessarily be applicable to this product.
 NCBI GI #    83367077
 NCBI GeneID    94025
 NCBI Accession #    NP_078966.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_024690.2 [Other Products]
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 UniProt Primary Accession #    Q8WXI7 [Other Products]
 UniProt Secondary Accession #    Q6ZQW5; Q96RK2 [Other Products]
 UniProt Related Accession #    Q8WXI7 [Other Products]
 Molecular Weight    2,353,428 Da
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 NCBI Official Full Name    mucin-16
 NCBI Official Synonym Full Names    mucin 16, cell surface associated
 NCBI Official Symbol    MUC16 [Similar Products]
 NCBI Official Synonym Symbols   
CA125
[Similar Products]
 NCBI Protein Information    mucin-16
 UniProt Protein Name    Mucin-16
 UniProt Synonym Protein Names   
Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125
 Protein Family    Mucin
 UniProt Gene Name    MUC16 [Similar Products]
 UniProt Synonym Gene Names    CA125; MUC-16; CA-125 [Similar Products]
 UniProt Entry Name    MUC16_HUMAN
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 UniProt Comments for MUC16    MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, peripheral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; integral to membrane; plasma membrane; vesicle

Molecular Function: protein binding

Biological Process: cell adhesion; cellular protein metabolic process; O-glycan processing; post-translational protein modification; protein amino acid O-linked glycosylation
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 Research Articles on MUC16    1. IL-6 was found to be strongly associated with advanced serous EOC and could be used in combination with serum CA125 to discriminate benign and epithelial ovarian carcinoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MUC16 antibodyPathways associated with anti-MUC16 antibody
 Reference Product  PubMed Publications
 MUC4 antibody  >60 publications with MUC16 and MUC4
 MUC5AC antibody  >46 publications with MUC16 and MUC5AC
 MUC2 antibody  >21 publications with MUC16 and MUC2
 MUC7 antibody  >11 publications with MUC16 and MUC7
 MUC17 antibody  >9 publications with MUC16 and MUC17
 MUC12 antibody  >7 publications with MUC16 and MUC12
 MUC3A antibody  >5 publications with MUC16 and MUC3A
 MUC19 antibody  >5 publications with MUC16 and MUC19
 MSLN antibody  >3 publications with MUC16 and MSLN
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Termination Of O-glycan Biosynthesis Pathway antibodies  Termination Of O-glycan Biosynthesis Pathway Diagram
Diseases associated with anti-MUC16 antibodyOrgans/Tissues associated with anti-MUC16 antibody
 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >248 publications with MUC16 and Ovarian Neoplasms
 Carcinoma Antibodies  >128 publications with MUC16 and Carcinoma
 Neoplasm Metastasis Antibodies  >39 publications with MUC16 and Neoplasm Metastasis
 Lung Neoplasms Antibodies  >23 publications with MUC16 and Lung Neoplasms
 Inflammation Antibodies  >22 publications with MUC16 and Inflammation
 Lung Diseases Antibodies  >19 publications with MUC16 and Lung Diseases
 Cardiovascular Diseases Antibodies  >15 publications with MUC16 and Cardiovascular Diseases
 Skin Diseases Antibodies  >14 publications with MUC16 and Skin Diseases
 Necrosis Antibodies  >14 publications with MUC16 and Necrosis
 Heart Diseases Antibodies  >12 publications with MUC16 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >272 publications with MUC16 and Blood
 Eye Antibodies  >59 publications with MUC16 and Eye
 Lung Antibodies  >39 publications with MUC16 and Lung
 Ovary Antibodies  >38 publications with MUC16 and Ovary
 Lymph Node Antibodies  >32 publications with MUC16 and Lymph Node
 Uterus Antibodies  >19 publications with MUC16 and Uterus
 Epididymis Antibodies  >17 publications with MUC16 and Epididymis
 Cervix Antibodies  >9 publications with MUC16 and Cervix
 Pancreas Antibodies  >8 publications with MUC16 and Pancreas
 Intestine Antibodies  >8 publications with MUC16 and Intestine
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