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anti-fbpA antibody :: Rabbit Mycobacterium tuberculosis Antigen 85-A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1489664
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mycobacterium tuberculosis Antigen 85-A (fbpA), Polyclonal Antibody

 Also Known As   

Rabbit anti-Mycobacterium tuberculosis Antigen 85-A polyclonal Antibody, Biotin conjugated

 Product Synonym Names    Antigen 85 complex A; Fibronectin-binding protein A Mycolyl transferase 85A; fbpA; mpt44
 Product Gene Name   

anti-fbpA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P9WQP3
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    MycoBacterium tuberculosis
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Biotin
 Immunogen    Recombinant Mycobacterium tuberculosis Antigen 85-A protein
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-fbpA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-fbpA antibody

   Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.
 Applications Tested/Suitable for anti-fbpA antibody   

Western Blot (WB), ELISA (EIA)

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 Western Blot (WB) of anti-fbpA antibody    western blot All lanes:Antigen 85-A antibody at 2ug/ml Lane 1: Recombinant Mycobacterium tuberculosis Antigen 85-A protein 1ug Lane 2: Recombinant Mycobacterium tuberculosis Antigen 85-A protein 10ug Secondary Goat polyclonal to rabbit IgG at 1/100
anti-fbpA antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for fbpA. It may not necessarily be applicable to this product.
 NCBI GI #    15610940
 NCBI GeneID    886132
 NCBI Accession #    NP_218321.1 [Other Products]
 NCBI GenBank Nucleotide #    NC_000962.3 [Other Products]
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 UniProt Primary Accession #    P9WQP3 [Other Products]
 UniProt Secondary Accession #    P0A4V2; P17944; P17996; D6MJP3; F2GDG3 [Other Products]
 UniProt Related Accession #    P9WQP3 [Other Products]
 Molecular Weight    35,686 Da [Similar Products]
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 NCBI Official Full Name    diacylglycerol acyltransferase/mycolyltransferase Ag85A
 NCBI Official Symbol    fbpA [Similar Products]
 NCBI Official Synonym Symbols   
85A; mpt44
[Similar Products]
 NCBI Protein Information    diacylglycerol acyltransferase/mycolyltransferase Ag85A
 UniProt Protein Name    Diacylglycerol acyltransferase/mycolyltransferase Ag85A
 UniProt Synonym Protein Names   
Acyl-CoA:diacylglycerol acyltransferase; Antigen 85 complex A; 85A; Ag85A; Fibronectin-binding protein A; Fbps A
 Protein Family    Major ferric iron-binding protein
 UniProt Gene Name    fbpA [Similar Products]
 UniProt Synonym Gene Names    mpt44; DGAT; 85A; Ag85A; Fbps A [Similar Products]
 UniProt Entry Name    A85A_MYCTU
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 UniProt Comments for fbpA    The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM. FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor. It has a preference for C26:0-CoA over C18:1-CoA.
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 Research Articles on fbpA    1. Using a prime and pull approach, lentivector vaccines expressing Ag85A induce immunogenicity but fail to induce protection against Mycobacterium bovis bacillus Calmette-Guerin challenge in mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Rabbit anti-Mycobacterium tuberculosis Antigen 85-A polyclonal Antibody, Biot
 Catalog #  Product Name  Catalog #  Product Name
 MBS1489034  Rabbit anti-Mycobacterium tuberculosis Antigen 85-A polyclonal Antibody, HRP conjugated  MBS1489664  Rabbit anti-Mycobacterium tuberculosis Antigen 85-A polyclonal Antibody, Biotin conjugated
 MBS1490301  Rabbit anti-Mycobacterium tuberculosis Antigen 85-A polyclonal Antibody, FITC  MBS1490476  Rabbit anti-Mycobacterium tuberculosis Antigen 85-A polyclonal Antibody
Pathways associated with anti-fbpA antibody
 Products by Pathway  Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
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