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anti-MyoD antibody :: Rabbit MyoD Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9402320
Western Blot (WB)
Unit / Price
0.05 mL  /  $200 +1 FREE 8GB USB
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MyoD, Polyclonal Antibody

 Also Known As   

MyoD (Phospho-Ser200) Antibody

 Product Synonym Names    MYF3; MYOD; MYOD1
 Product Gene Name   

anti-MyoD antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    159970
 3D Structure    ModBase 3D Structure for P15172
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    The antibody detects endogenous level of MyoD only when phosphorylated at serine 200.
 Purity/Purification    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
 Form/Format    Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1.0 mg/ml (lot specific)
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 Immunogen Type    Peptide-KLH
 Immunogen Description    Peptide sequence around phosphorylation site of serine 200 (A-S-S(p)-P-R) derived from Human MyoD.
 Modification    Phospho-Ser200
 Target Name    MyoD
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 Preparation and Storage    Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.
 Other Notes    Small volumes of anti-MyoD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MyoD antibody

   MyoD encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the
 Product Categories/Family for anti-MyoD antibody    Phospho-specific Ab
 Applications Tested/Suitable for anti-MyoD antibody   

Western Blot (WB)

 Application Notes for anti-MyoD antibody    Western blotting: 1:500~1:1000
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 Western Blot (WB) of anti-MyoD antibody    Western blot analysis of extracts from Hela cells untreated or treated with EGF using MyoD(Phospho-Ser200) Antibody.
anti-MyoD antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MyoD. It may not necessarily be applicable to this product.
 NCBI GI #    23111009
 NCBI GeneID    4654
 NCBI Accession #    NP_002469.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002478.4 [Other Products]
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 UniProt Primary Accession #    P15172 [Other Products]
 UniProt Secondary Accession #    O75321 [Other Products]
 UniProt Related Accession #    P15172 [Other Products]
 Molecular Weight    34,501 Da
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 NCBI Official Full Name    myoblast determination protein 1
 NCBI Official Synonym Full Names    myogenic differentiation 1
 NCBI Official Symbol    MYOD1 [Similar Products]
 NCBI Official Synonym Symbols   
PUM; MYF3; MYOD; bHLHc1
[Similar Products]
 NCBI Protein Information    myoblast determination protein 1
 UniProt Protein Name    Myoblast determination protein 1
 UniProt Synonym Protein Names   
Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3
 Protein Family    Myosin
 UniProt Gene Name    MYOD1 [Similar Products]
 UniProt Synonym Gene Names    BHLHC1; MYF3; MYOD; bHLHc1; Myf-3 [Similar Products]
 UniProt Entry Name    MYOD1_HUMAN
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 NCBI Summary for MyoD    This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MyoD    MyoD: a transcription factor of the basic helix-loop-helix family and the myogenic factors subfamily. Involved in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. It is involved in muscle cell differentiation, and is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis.

Protein type: DNA-binding; Transcription factor; RNA splicing

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: nucleoplasm; transcription factor complex; myofibril; nuclear chromatin; cytoplasm; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; chromatin DNA binding; protein heterodimerization activity; ubiquitin protein ligase binding; transcription coactivator activity; transcription factor binding; nuclear hormone receptor binding

Biological Process: transcription from RNA polymerase II promoter; skeletal muscle development; muscle development; skeletal muscle fiber adaptation; positive regulation of skeletal muscle regeneration; regulation of RNA splicing; myotube differentiation involved in skeletal muscle regeneration; muscle cell fate commitment; skeletal muscle fiber development; myotube cell development; cellular response to starvation; protein amino acid phosphorylation; positive regulation of myoblast differentiation; regulation of transcription from RNA polymerase II promoter; muscle cell differentiation; positive regulation of skeletal muscle fiber development; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; myoblast cell fate determination; regulation of alternative nuclear mRNA splicing, via spliceosome
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 Research Articles on MyoD    1. MUNC is not a classic cis-acting enhancer RNA (e-RNA) acting exclusively by stimulating the neighboring MyoD gene
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MyoD antibodyPathways associated with anti-MyoD antibody
 Reference Product  PubMed Publications
 JUN antibody  >85 publications with MyoD and JUN
 MEF2C antibody  >22 publications with MyoD and MEF2C
 TCF3 antibody  >16 publications with MyoD and TCF3
 SMAD3 antibody  >8 publications with MyoD and SMAD3
 ID1 antibody  >8 publications with MyoD and ID1
 MEF2A antibody  >6 publications with MyoD and MEF2A
 MYB antibody  >3 publications with MyoD and MYB
 CREBBP antibody  >2 publications with MyoD and CREBBP
 EP300 antibody  >2 publications with MyoD and EP300
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 CDO In Myogenesis Pathway antibodies  CDO In Myogenesis Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Myogenesis Pathway antibodies  Myogenesis Pathway Diagram
 Notch-mediated HES/HEY Network Pathway antibodies  Notch-mediated HES/HEY Network Pathway Diagram
 Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies  Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram
 Signaling Events Mediated By HDAC Class III Pathway antibodies  Signaling Events Mediated By HDAC Class III Pathway Diagram
 MiRs In Muscle Cell Differentiation Pathway antibodies  MiRs In Muscle Cell Differentiation Pathway Diagram
Diseases associated with anti-MyoD antibodyOrgans/Tissues associated with anti-MyoD antibody
 Disease Name  Pubmed Publications
 Rhabdomyosarcoma, Embryonal Antibodies  >75 publications with MyoD and Rhabdomyosarcoma, Embryonal
 Necrosis Antibodies  >32 publications with MyoD and Necrosis
 Inflammation Antibodies  >23 publications with MyoD and Inflammation
 Muscular Atrophy Antibodies  >23 publications with MyoD and Muscular Atrophy
 Cell Transformation, Neoplastic Antibodies  >20 publications with MyoD and Cell Transformation, Neoplastic
 Cardiovascular Diseases Antibodies  >15 publications with MyoD and Cardiovascular Diseases
 Heart Diseases Antibodies  >13 publications with MyoD and Heart Diseases
 Lung Diseases Antibodies  >13 publications with MyoD and Lung Diseases
 Lung Neoplasms Antibodies  >13 publications with MyoD and Lung Neoplasms
 Breast Neoplasms Antibodies  >12 publications with MyoD and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >728 publications with MyoD and Muscle
 Heart Antibodies  >48 publications with MyoD and Heart
 Eye Antibodies  >13 publications with MyoD and Eye
 Lymph Antibodies  >11 publications with MyoD and Lymph
 Placenta Antibodies  >2 publications with MyoD and Placenta
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