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anti-NAGLU antibody :: Rabbit anti-Human N-Acetyl Alpha-D-Glucosaminidase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2027566 (3 units are in stock [0.1 mg] for immediate shipment)
Western Blot
Unit / Price
0.01 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $235 +1 FREE 8GB USB
0.1 mg  /  $320 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

N-Acetyl Alpha-D-Glucosaminidase (NAGLU), Polyclonal Antibody

 Also Known As   

Polyclonal Antibody to N-Acetyl Alpha-D-Glucosaminidase (NAGLU)

 Product Gene Name   

anti-NAGLU antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant NAGLU (Val485~Trp743) expressed in E.coli
    
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for two years.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-NAGLU antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-NAGLU antibody   

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM

 Application Notes for anti-NAGLU antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml

Optimal working dilutions must be determined by end user
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 Western Blot of anti-NAGLU antibody    anti-NAGLU antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for NAGLU. It may not necessarily be applicable to this product.
 NCBI GI #    2660688
 NCBI GeneID    27419
 NCBI Accession #    AAB88084.1 [Other Products]
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 NCBI Official Full Name    Naglu
 NCBI Official Synonym Full Names    alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
 NCBI Official Symbol    Naglu [Similar Products]
 NCBI Protein Information    alpha-N-acetylglucosaminidase
 UniProt Protein Name    Naglu
 UniProt Synonym Protein Names   
Naglu
 Protein Family    Alpha-N-acetylglucosaminidase
 UniProt Gene Name    Naglu [Similar Products]
 UniProt Entry Name    O54752_MOUSE
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 UniProt Comments for NAGLU    NAGLU: Involved in the degradation of heparan sulfate. Defects in NAGLU are the cause of mucopolysaccharidosis type 3B (MPS3B); also known as Sanfilippo syndrome B. MPS3B is a form of mucopolysaccharidosis type 3, an autosomal recessive lysosomal storage disease due to impaired degradation of heparan sulfate. MPS3 is characterized by severe central nervous system degeneration, but only mild somatic disease. Onset of clinical features usually occurs between 2 and 6 years; severe neurologic degeneration occurs in most patients between 6 and 10 years of age, and death occurs typically during the second or third decade of life.

Protein type: Hydrolase; EC 3.2.1.50; Glycan Metabolism - glycosaminoglycan degradation

Molecular Function: alpha-N-acetylglucosaminidase activity

Biological Process: locomotor rhythm; retinal rod cell development; inner ear receptor cell development; lysosome organization and biogenesis; cerebellar Purkinje cell layer development; middle ear morphogenesis
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 Research Articles on NAGLU    1. In the 1-h test, MPS IIIB mice were hyperactive, with increased rapid exploratory behaviour and reduced immobility time.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-NAGLU antibody
 Products by Pathway  Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 HS-GAG Degradation Pathway antibodies  HS-GAG Degradation Pathway Diagram
 Heparan Sulfate Degradation Pathway antibodies  Heparan Sulfate Degradation Pathway Diagram
 Heparan Sulfate Degradation Pathway antibodies  Heparan Sulfate Degradation Pathway Diagram
 Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway antibodies  Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
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