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anti-PGLYRP2 antibody :: Rabbit anti-Human N-acetylmuramoyl-L-alanine amidase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1490646
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

N-acetylmuramoyl-L-alanine amidase (PGLYRP2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human N-acetylmuramoyl-L-alanine amidase polyclonal Antibody

 Product Synonym Names    Peptidoglycan recognition protein 2 Peptidoglycan recognition protein long PGLYRP2 PGLYRPL; PGRPL UNQ3103/PRO10102
 Product Gene Name   

anti-PGLYRP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608199
 3D Structure    ModBase 3D Structure for Q96PD5
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human N-acetylmuramoyl-L-alanine amidase protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54941 / sc-54662 / sc-54943 / sc-50470
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PGLYRP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PGLYRP2 antibody

   May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
 Applications Tested/Suitable for anti-PGLYRP2 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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 Immunohistochemistry (IHC) of anti-PGLYRP2 antibody    Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS1490646 at dilution of 1:100
anti-PGLYRP2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-PGLYRP2 antibody    Immunohistochemistry of paraffin-embedded human liver cancer using MBS1490646 at dilution of 1:100
anti-PGLYRP2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for PGLYRP2. It may not necessarily be applicable to this product.
 NCBI GI #    156616294
 NCBI GeneID    114770
 NCBI Accession #    NP_443122.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_052890.3 [Other Products]
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 UniProt Primary Accession #    Q96PD5 [Other Products]
 UniProt Secondary Accession #    Q68CK1; Q96N74; Q9UC60; A8K050; A8K8C7; B2RMZ2; B7ZM33 [Other Products]
 UniProt Related Accession #    Q96PD5 [Other Products]
 Molecular Weight    68,000 Da [Similar Products]
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 NCBI Official Full Name    N-acetylmuramoyl-L-alanine amidase
 NCBI Official Synonym Full Names    peptidoglycan recognition protein 2
 NCBI Official Symbol    PGLYRP2 [Similar Products]
 NCBI Official Synonym Symbols   
tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
[Similar Products]
 NCBI Protein Information    N-acetylmuramoyl-L-alanine amidase
 UniProt Protein Name    N-acetylmuramoyl-L-alanine amidase
 UniProt Synonym Protein Names   
Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L
 Protein Family    N-acetylmuramoyl-L-alanine amidase
 UniProt Gene Name    PGLYRP2 [Similar Products]
 UniProt Synonym Gene Names    PGLYRPL; PGRPL; PGRP-L [Similar Products]
 UniProt Entry Name    PGRP2_HUMAN
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 NCBI Summary for PGLYRP2    This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]
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 UniProt Comments for PGLYRP2    PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Receptor, misc.; Hydrolase; EC 3.5.1.28

Chromosomal Location of Human Ortholog: 19p13.12

Cellular Component: intracellular; membrane

Molecular Function: N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity; zinc ion binding

Biological Process: defense response to Gram-positive bacterium; detection of bacterium; innate immune response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation during immune response; pattern recognition receptor signaling pathway; peptide amidation; peptidoglycan catabolic process; regulation of inflammatory response
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 Research Articles on PGLYRP2    1. This study demonistrated that PGLYRP2 single-nucleotide polymorphisms is risk of Parkinson's disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PGLYRP2 antibodyDiseases associated with anti-PGLYRP2 antibody
 Reference Product  PubMed Publications
 NOD2 antibody  >5 publications with PGLYRP2 and NOD2
 JUN antibody  >4 publications with PGLYRP2 and JUN
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with PGLYRP2 and Inflammation
 Edema Antibodies  >1 publications with PGLYRP2 and Edema
 Immune System Diseases Antibodies  >1 publications with PGLYRP2 and Immune System Diseases
 Nervous System Diseases Antibodies  >1 publications with PGLYRP2 and Nervous System Diseases
 Weight Loss Antibodies  >1 publications with PGLYRP2 and Weight Loss
 Hyperplasia Antibodies  >1 publications with PGLYRP2 and Hyperplasia
 Liver Diseases Antibodies  >1 publications with PGLYRP2 and Liver Diseases
Organs/Tissues associated with anti-PGLYRP2 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with PGLYRP2 and Liver
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