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anti-NADH antibody :: Rabbit anti-Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1491106
Immunohistochemistry (IHC)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 polyclonal Antibody

 Product Synonym Names    Complex I-B8; NADH-ubiquinone oxidoreductase B8 subunit; NDUFA2
 Product Gene Name   

anti-NADH antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602137
 3D Structure    ModBase 3D Structure for O43678
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-107019 / sc-107020
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-NADH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NADH antibody

   Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
 Applications Tested/Suitable for anti-NADH antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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 Immunohistochemistry (IHC) of anti-NADH antibody    Immunohistochemistry of paraffin-embedded human kidney using MBS1491106 at dilution 1:100
anti-NADH antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for NADH. It may not necessarily be applicable to this product.
 NCBI GI #    297206774
 NCBI GeneID    4695
 NCBI Accession #    NP_001171941.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001185012.1 [Other Products]
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 UniProt Primary Accession #    O43678 [Other Products]
 UniProt Secondary Accession #    Q6IAY8; D6RJD6 [Other Products]
 UniProt Related Accession #    O43678 [Other Products]
 Molecular Weight    8,491 Da
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 NCBI Official Full Name    NADH dehydrogenase
 NCBI Official Synonym Full Names    NADH:ubiquinone oxidoreductase subunit A2
 NCBI Official Symbol    NDUFA2 [Similar Products]
 NCBI Official Synonym Symbols   
B8; CD14; CIB8
[Similar Products]
 NCBI Protein Information    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
 UniProt Protein Name    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
 UniProt Synonym Protein Names   
Complex I-B8; CI-B8; NADH-ubiquinone oxidoreductase B8 subunit
 Protein Family    NADH dehydrogenase
 UniProt Gene Name    NDUFA2 [Similar Products]
 UniProt Synonym Gene Names    CI-B8 [Similar Products]
 UniProt Entry Name    NDUA2_HUMAN
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 NCBI Summary for NADH    The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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 UniProt Comments for NADH    NDUFA2: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Protein type: Oxidoreductase; EC 1.6.5.3; EC 1.6.99.3; Mitochondrial; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 5q31.2

Cellular Component: mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex I

Molecular Function: NADH dehydrogenase (ubiquinone) activity

Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly

Disease: Leigh Syndrome
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 Research Articles on NADH    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NADH antibodyPathways associated with anti-NADH antibody
 Reference Product  PubMed Publications
 NDUFS8 antibody  >2 publications with NADH and NDUFS8
 NDUFV2 antibody  >2 publications with NADH and NDUFV2
 NDUFA7 antibody  >2 publications with NADH and NDUFA7
 NDUFB8 antibody  >2 publications with NADH and NDUFB8
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Complex I Biogenesis Pathway antibodies  Complex I Biogenesis Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
Diseases associated with anti-NADH antibodyOrgans/Tissues associated with anti-NADH antibody
 Disease Name  Pubmed Publications
 Leigh Disease Antibodies  >1 publications with NADH and Leigh Disease
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with NADH and Muscle
 Bone Antibodies  >1 publications with NADH and Bone
 Blood Antibodies  >1 publications with NADH and Blood
 Bone Marrow Antibodies  >1 publications with NADH and Bone Marrow
 Skin Antibodies  >1 publications with NADH and Skin
 Heart Antibodies  >1 publications with NADH and Heart
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