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anti-NAPSIN A antibody :: Rabbit NAPSIN A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS540164 anti-NAPSIN A antibody
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NAPSIN A, Polyclonal Antibody

 Also Known As   

NAPSIN A Antibody

 Product Synonym Names    ASP 4 antibody Aspartyl protease 4; KAP; Kdap; Kidney derived aspartic protease like protein; NAP1; NAPA; NAPSA; Napsin 1; napsin A aspartic peptidase antibody Pronapsin A; SNAPA; TA01/TA02 antibody
 Product Gene Name   

anti-NAPSIN A antibody

[Similar Products]
 Matching Pairs    Antibody: NAPSIN A (MBS540164)
Positive Control: NAPSIN A (MBS542978)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605631
 3D Structure    ModBase 3D Structure for O96009
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Form/Format    Affinity Purified
 Concentration    0.85-1.25 ug/ul in antibody stabilization buffer (lot specific)
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 Immunogen    Synthetic peptide taken within amino acid region 1-50 on human Napsin A protein.
 Immunoglobulin    IgG
 Expression    Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.
 Determinant    N-epitope
 Molecular Function    aspartic-type endopeptidase activity; peptidase activity
 Structure    Belongs to the peptidase A1 family.
 Subcellular Location    alveolar lamellar body; Extracellular space; Extracellular vesicular exosome; lysosome
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-NAPSIN A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-NAPSIN A antibody

   Affinity Purified Napsin A aspartic peptidase Antibody N-epitope
May be involved in processing of pneumocyte surfactant precursors
 Product Categories/Family for anti-NAPSIN A antibody    Primary Antibodies; Cell Biology; Tags and Cell Markers; NAPSIN A Antibody
 Applications Tested/Suitable for anti-NAPSIN A antibody   

ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)

 Application Notes for anti-NAPSIN A antibody    Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500
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NCBI/Uniprot data below describe general gene information for NAPSIN A. It may not necessarily be applicable to this product.
 NCBI GI #    119592254
 NCBI GeneID    9476
 NCBI Accession #    EAW71848.1 [Other Products]
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 UniProt Primary Accession #    O96009 [Other Products]
 UniProt Secondary Accession #    Q8WWD9 [Other Products]
 UniProt Related Accession #    O96009 [Other Products]
 Molecular Weight    45,387 Da
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 NCBI Official Full Name    napsin A aspartic peptidase, isoform CRA_b
 NCBI Official Synonym Full Names    napsin A aspartic peptidase
 NCBI Official Symbol    NAPSA [Similar Products]
 NCBI Official Synonym Symbols   
KAP; Kdap; NAP1; NAPA; SNAPA
[Similar Products]
 NCBI Protein Information    napsin-A
 UniProt Protein Name    Napsin-A
 UniProt Synonym Protein Names   
Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02
 UniProt Gene Name    NAPSA [Similar Products]
 UniProt Synonym Gene Names    NAP1; NAPA; ASP4; Asp 4 [Similar Products]
 UniProt Entry Name    NAPSA_HUMAN
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 NCBI Summary for NAPSIN A    This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
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 UniProt Comments for NAPSIN A    NAPSA: May be involved in processing of pneumocyte surfactant precursors. Belongs to the peptidase A1 family.

Protein type: Protease; EC 3.4.23.-; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space; lysosome

Molecular Function: aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity

Biological Process: cellular protein metabolic process; membrane protein proteolysis; protein catabolic process; proteolysis; surfactant homeostasis
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 Research Articles on NAPSIN A    1. napsin A is another sensitive and specific marker for distinguishing ovarian clear cell tumors (especially adenocarcinomas) from other ovarian tumors
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-NAPSIN A antibodyDiseases associated with anti-NAPSIN A antibody
 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Surfactant Metabolism Pathway antibodies  Surfactant Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >9 publications with NAPSIN A and Kidney Diseases
 Liver Neoplasms Antibodies  >4 publications with NAPSIN A and Liver Neoplasms
 Fibrosis Antibodies  >3 publications with NAPSIN A and Fibrosis
 Neoplasms, Experimental Antibodies  >3 publications with NAPSIN A and Neoplasms, Experimental
 Carcinoma, Hepatocellular Antibodies  >2 publications with NAPSIN A and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with NAPSIN A and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with NAPSIN A and Cardiovascular Diseases
 Hyperplasia Antibodies  >1 publications with NAPSIN A and Hyperplasia
 Disease Models, Animal Antibodies  >1 publications with NAPSIN A and Disease Models, Animal
 Skin Neoplasms Antibodies  >1 publications with NAPSIN A and Skin Neoplasms
Organs/Tissues associated with anti-NAPSIN A antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >81 publications with NAPSIN A and Lung
 Kidney Antibodies  >18 publications with NAPSIN A and Kidney
 Uterus Antibodies  >3 publications with NAPSIN A and Uterus
 Prostate Antibodies  >3 publications with NAPSIN A and Prostate
 Spleen Antibodies  >2 publications with NAPSIN A and Spleen
 Trachea Antibodies  >1 publications with NAPSIN A and Trachea
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