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anti-NCAM2 antibody :: Goat NCAM2/OCAM Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421506
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NCAM2/OCAM, Polyclonal Antibody

★Popular Item★
 Also Known As   

Goat anti-NCAM2/OCAM Antibody

 Product Synonym Names    NCAM2; neural cell adhesion molecule 2; HGNC: 7657; MGC51008; NCAM21; OCAM; NCAM2 antibody; neural cell adhesion molecule 2 antibody; HGNC: 7657 antibody; MGC51008 antibody; NCAM21 antibody; OCAM antibody; NCAM2 / OCAM
 Product Gene Name   

anti-NCAM2 antibody

[Similar Products]
 Product Synonym Gene Name    OCAM [Similar Products]
 Antibody/Peptide Pairs    NCAM2 / OCAM peptide (MBS425485) is used for blocking the activity of NCAM2/OCAM antibody (MBS421506)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KVSNDIIQSK EDDSK
 OMIM    602040
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human, Mouse
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
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 Immunogen    Peptide with sequence C-KVSNDIIQSKEDDSK, from the C Terminus of the protein sequence according to NP_004531.2.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-NCAM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-NCAM2 antibody   

Peptide ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-NCAM2 antibody    Peptide ELISA: Antibody detection limit dilution 1: 4000.


Western Blot: Preliminary experiments gave an approx 150 and 28kDa bands in Human and Mouse Brain lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 93. 0kDa according to NP_004531.2. Both observed bands were successfully blocked by incubation with the immunizing peptide.


Immunohistochemistry: Frozen section of Olfactory bulb from transcardially PFA-perfused Mouse shows strong staining of axon bundles (right side middle, figure 1) and moderate peripheral staining outside the glomeruli (top, figure 1). NCAM2 (red) is stained complementary to VGLUT2 (blue) and NQO1 (green) in figure 2. Recommended concentration:0.5 ug/mL. Paraffin embedded Human Brain (Cortex). Recommended concentration is: 3.75ug/ml.
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 Immunofluorescence (IF) of anti-NCAM2 antibody    (0.5ug/ml) 24h-staining of PFA-perfused cryosection of Mouse Olfactory bub. Antigen retrieval with methanol (-20C, 10min) followed by 1% SDS(10min), IF-staning. Data obtained from anonymous customer.
anti-NCAM2 antibody Immunofluorescence (IF) image
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 Immunofluorescence (IF) of anti-NCAM2 antibody    (0.5ug/ml) 48h-staining of PFA-perfused cryosection of Mouse Olfactory bulb. Antigen retrieval with citrate buffer pH 6 at 95C for 10min, IF-staning for NCAM2 (red), VGLUT2 (blue) and NQO1 (green), data obtained from anonymus customer.
anti-NCAM2 antibody Immunofluorescence (IF) image
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 Testing Data(TD) of anti-NCAM2 antibody    (3.75 ug/mL) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH, AP-staining.
anti-NCAM2 antibody Testing Data(TD) image
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NCBI/Uniprot data below describe general gene information for NCAM2. It may not necessarily be applicable to this product.
 NCBI GI #    33519481
 NCBI GeneID    4685
 NCBI Accession #    NP_004531.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004540.3 [Other Products]
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 UniProt Secondary Accession #    Q7Z7F2; A8MQ06; B7Z841 [Other Products]
 UniProt Related Accession #    O15394 [Other Products]
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 NCBI Official Full Name    neural cell adhesion molecule 2
 NCBI Official Synonym Full Names    neural cell adhesion molecule 2
 NCBI Official Symbol    NCAM2 [Similar Products]
 NCBI Official Synonym Symbols   
NCAM21
[Similar Products]
 NCBI Protein Information    neural cell adhesion molecule 2
 UniProt Protein Name    Neural cell adhesion molecule 2
 Protein Family    Neural cell adhesion molecule
 UniProt Gene Name    NCAM2 [Similar Products]
 UniProt Synonym Gene Names    NCAM21; N-CAM-2; NCAM-2 [Similar Products]
 UniProt Entry Name    NCAM2_HUMAN
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 NCBI Summary for NCAM2    The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may function in selective fasciculation and zone-to-zone projection of the primary olfactory axons. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NCAM2    NCAM2: May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 21q21.1

Cellular Component: axon; integral to membrane; plasma membrane

Biological Process: neuron adhesion
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 Research Articles on NCAM2    1. A complete structural model of the entire ectodomain of human NCAM2 has been assembled from crystal structures of six recombinant proteins corresponding to different regions of the ectodomain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-NCAM2 antibodyDiseases associated with anti-NCAM2 antibody
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
 Disease Name  Pubmed Publications
 Abnormalities, Multiple Antibodies  >5 publications with NCAM2 and Abnormalities, Multiple
 Brain Diseases Antibodies  >3 publications with NCAM2 and Brain Diseases
 Prostatic Diseases Antibodies  >3 publications with NCAM2 and Prostatic Diseases
 Lung Diseases Antibodies  >2 publications with NCAM2 and Lung Diseases
 Breast Neoplasms Antibodies  >2 publications with NCAM2 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with NCAM2 and Disease Models, Animal
 Inflammation Antibodies  >1 publications with NCAM2 and Inflammation
 Hyperplasia Antibodies  >1 publications with NCAM2 and Hyperplasia
 Necrosis Antibodies  >1 publications with NCAM2 and Necrosis
Organs/Tissues associated with anti-NCAM2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >31 publications with NCAM2 and Brain
 Nerve Antibodies  >12 publications with NCAM2 and Nerve
 Embryonic Tissue Antibodies  >4 publications with NCAM2 and Embryonic Tissue
 Prostate Antibodies  >3 publications with NCAM2 and Prostate
 Blood Antibodies  >2 publications with NCAM2 and Blood
 Lung Antibodies  >2 publications with NCAM2 and Lung
 Testis Antibodies  >2 publications with NCAM2 and Testis
 Vascular Antibodies  >1 publications with NCAM2 and Vascular
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