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anti-NPY4R antibody :: Sheep NEUROPEPTIDE Y RECEPTOR 4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS221025 anti-NPY4R antibody
Unit / Price
1 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NEUROPEPTIDE Y RECEPTOR 4 (NPY4R), Polyclonal Antibody

 Also Known As   

SHEEP ANTI HUMAN NEUROPEPTIDE Y RECEPTOR 4

 Product Gene Name   

anti-NPY4R antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    (L-)P-L-E- E-S-E-H-L- P-L-S-T-V
 OMIM    601790
 3D Structure    ModBase 3D Structure for P50391
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Sheep
 Species Reactivity    Chimpanzee (Expected from Sequence)
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 Specificity    This item recognizes human neuropeptide Y receptor type 4, a membrane protein thought to be involved in the control of feeding.
 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 5.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
Preparation
 Immunogen    Synthetic peptide corresponding to the amino acids 345 - 357 of the native molecule conjugated to Keyhole limpet Haemocyanin.
Histology Positive Control Tissue
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-NPY4R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-NPY4R antibody

   MBS221025 recognizes human neuropeptide Y receptor type 4, a membrane protein thought to be involved in the control of feeding.
 Applications Tested/Suitable for anti-NPY4R antibody   

ELISA (EIA), Immunohistology Paraffin

 Application Notes for anti-NPY4R antibody    Immunohistology: This product does not require protein digestion pre-treatment or antigen retrieval using heat treatment prior to staining of paraffin sections.
Immunohistology - Paraffin: Minimum Dilution: 1/50; Maximum Dilution: 1/500
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NCBI/Uniprot data below describe general gene information for NPY4R. It may not necessarily be applicable to this product.
 NCBI GI #    523704349
 NCBI GeneID    5540
 NCBI Accession #    NP_001265723.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001278794.1 [Other Products]
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 UniProt Primary Accession #    P50391 [Other Products]
 UniProt Secondary Accession #    Q13456; Q5ISU3; Q5T2X9; Q6FH06 [Other Products]
 UniProt Related Accession #    P50391 [Other Products]
 Molecular Weight    42,195 Da [Similar Products]
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 NCBI Official Full Name    neuropeptide Y receptor type 4
 NCBI Official Synonym Full Names    neuropeptide Y receptor Y4
 NCBI Official Symbol    NPY4R [Similar Products]
 NCBI Official Synonym Symbols   
Y4; PP1; PPYR1; NPY4-R
[Similar Products]
 NCBI Protein Information    neuropeptide Y receptor type 4; pancreatic polypeptide receptor 1
 UniProt Protein Name    Neuropeptide Y receptor type 4
 UniProt Synonym Protein Names   
Pancreatic polypeptide receptor 1; PP1
 Protein Family    Neuropeptide Y receptor
 UniProt Gene Name    NPY4R [Similar Products]
 UniProt Synonym Gene Names    PPYR1; NPY4-R; PP1 [Similar Products]
 UniProt Entry Name    NPY4R_HUMAN
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 UniProt Comments for NPY4R    NPY4R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; peptide YY receptor activity; pancreatic polypeptide receptor activity; peptide binding

Biological Process: G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; blood circulation; digestion; feeding behavior
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 Research Articles on NPY4R    1. Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NPY4R antibodyPathways associated with anti-NPY4R antibody
 Reference Product  PubMed Publications
 NPY1R antibody  >3 publications with NPY4R and NPY1R
 NPY antibody  >3 publications with NPY4R and NPY
 NPY5R antibody  >2 publications with NPY4R and NPY5R
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Organs/Tissues associated with anti-NPY4R antibody
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >1 publications with NPY4R and Intestine
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