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anti-NGFR P75 antibody :: Rabbit anti-Human NGFR P75 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS852713
Testing Data
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NGFR P75, Polyclonal Antibody

 Also Known As   

NGFR P75 Antibody

 Product Gene Name   

anti-NGFR P75 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    162010
 3D Structure    ModBase 3D Structure for P08138
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Purified by protein A column containing 0.02% NaN3
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.
 Other Notes    Small volumes of anti-NGFR P75 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NGFR P75 antibody

   Rabbit polyclonal NGFR p75 (1) antibody was raised against a 14 amino acid peptide from the intermediate residues of human NGFR P75 protein.
 Product Categories/Family for anti-NGFR P75 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-NGFR P75 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-NGFR P75 antibody    Peptide ELISA: 1:40,000-1:80,000
WB: 1:200-1,000
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 Testing Data of anti-NGFR P75 antibody    anti-NGFR P75 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for NGFR P75. It may not necessarily be applicable to this product.
 NCBI GI #    4505393
 NCBI GeneID    4804
 NCBI Accession #    NP_002498.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002507.3 [Other Products]
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 UniProt Primary Accession #    P08138 [Other Products]
 UniProt Secondary Accession #    B2R961; B4E096 [Other Products]
 UniProt Related Accession #    P08138 [Other Products]
 Molecular Weight    35,767 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 16
 NCBI Official Synonym Full Names    nerve growth factor receptor
 NCBI Official Symbol    NGFR [Similar Products]
 NCBI Official Synonym Symbols   
CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 16
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 16
 UniProt Synonym Protein Names   
Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD_antigen: CD271
 UniProt Gene Name    NGFR [Similar Products]
 UniProt Synonym Gene Names    TNFRSF16; NGF receptor [Similar Products]
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 NCBI Summary for NGFR P75    Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NGFR P75    Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
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Product References and Citations for anti-NGFR P75 antibody

   (1) Jin, H., Pan, Y., Zhao, L., et, al p75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells. Neoplasia.2007; 9 (6): 471-478.
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 Research Articles on NGFR P75    1. Collectively, CD271 initiates tumor formation by increasing the cell proliferation capacity through CDKN1C suppression and ERK-signaling activation, and by accelerating the migration signaling pathway in hypopharyngeal cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NGFR P75 antibodyPathways associated with anti-NGFR P75 antibody
 Reference Product  PubMed Publications
 NGF antibody  >232 publications with NGFR P75 and NGF
 NTRK1 antibody  >101 publications with NGFR P75 and NTRK1
 NTRK2 antibody  >30 publications with NGFR P75 and NTRK2
 NTRK3 antibody  >17 publications with NGFR P75 and NTRK3
 MAG antibody  >3 publications with NGFR P75 and MAG
 NTF4 antibody  >3 publications with NGFR P75 and NTF4
 MAPK1 antibody  >2 publications with NGFR P75 and MAPK1
 GRB2 antibody  >2 publications with NGFR P75 and GRB2
 RTN4R antibody  >2 publications with NGFR P75 and RTN4R
 SHC1 antibody  >2 publications with NGFR P75 and SHC1
 Products by Pathway  Pathway Diagram
 Axonal Growth Inhibition (RHOA Activation) Pathway antibodies  Axonal Growth Inhibition (RHOA Activation) Pathway Diagram
 Axonal Growth Stimulation Pathway antibodies  Axonal Growth Stimulation Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 Ceramide Signalling Pathway antibodies  Ceramide Signalling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 NADE Modulates Death Signalling Pathway antibodies  NADE Modulates Death Signalling Pathway Diagram
 NF-kB Is Activated And Signals Survival Pathway antibodies  NF-kB Is Activated And Signals Survival Pathway Diagram
 NFG And ProNGF Binds To P75NTR Pathway antibodies  NFG And ProNGF Binds To P75NTR Pathway Diagram
Diseases associated with anti-NGFR P75 antibodyOrgans/Tissues associated with anti-NGFR P75 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >158 publications with NGFR P75 and Neoplasms
 Nervous System Diseases Antibodies  >116 publications with NGFR P75 and Nervous System Diseases
 Brain Diseases Antibodies  >56 publications with NGFR P75 and Brain Diseases
 Necrosis Antibodies  >40 publications with NGFR P75 and Necrosis
 Neurodegenerative Diseases Antibodies  >34 publications with NGFR P75 and Neurodegenerative Diseases
 Nerve Degeneration Antibodies  >31 publications with NGFR P75 and Nerve Degeneration
 Inflammation Antibodies  >23 publications with NGFR P75 and Inflammation
 Disease Models, Animal Antibodies  >23 publications with NGFR P75 and Disease Models, Animal
 Mental Disorders Antibodies  >20 publications with NGFR P75 and Mental Disorders
 Kidney Diseases Antibodies  >14 publications with NGFR P75 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >184 publications with NGFR P75 and Brain
 Mixed Antibodies  >9 publications with NGFR P75 and Mixed
 Spleen Antibodies  >3 publications with NGFR P75 and Spleen
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