P46087.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
NCBI Official Synonym Full Names
NOP2 nucleolar protein
NCBI Protein Information
probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
UniProt Protein Name
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
UniProt Synonym Protein Names
Nucleolar protein 1; Nucleolar protein 2 homolog; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120
UniProt Synonym Gene Names
UniProt Comments for NOP2
NOP2: May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase. Belongs to the methyltransferase superfamily. RsmB/NOP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation; EC 2.1.1.-; Methyltransferase; Nucleolus; RNA-binding
Chromosomal Location of Human Ortholog: 12p13.31
Cellular Component: nucleolus; nucleoplasm
Molecular Function: protein binding; RNA binding; rRNA (cytosine-C5-967)-methyltransferase activity
Biological Process: maturation of LSU-rRNA; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter
Research Articles on NOP2
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Products associated with anti-NOP2 antibody
Pathways associated with anti-NOP2 antibody
Diseases associated with anti-NOP2 antibody
Organs/Tissues associated with anti-NOP2 antibody
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