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anti-NOSTRIN antibody :: Rabbit anti-Human, mouse NOSTRIN Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7002625
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NOSTRIN, Polyclonal Antibody

★Popular Item★
 Also Known As   

NOSTRIN Antibody

 Product Synonym Names    Nostrin; NOSTRIN; BM247 homolog; Nitric oxide synthase traffic inducer; Nitric oxide synthase trafficker; eNOS-trafficking inducer
 Product Gene Name   

anti-NOSTRIN antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607496
 3D Structure    ModBase 3D Structure for Q8IVI9
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, mouse
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 Purity/Purification    Affinity Purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Nostrin protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-51345 / sc-51347 / sc-134803
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-NOSTRIN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NOSTRIN antibody

   Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
 Applications Tested/Suitable for anti-NOSTRIN antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-NOSTRIN antibody    Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
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 Western Blot (WB) of anti-NOSTRIN antibody    Western blot
All lanes: NOSTRIN antibody at 6ug/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse brain tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 58,55,49,65 kDa
Observed band size: 58 kDa

anti-NOSTRIN antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-NOSTRIN antibody    Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7002625 at dilution of 1:100
anti-NOSTRIN antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-NOSTRIN antibody    Immunohistochemistry of paraffin-embedded human heart tissue using MBS7002625 at dilution of 1:100
anti-NOSTRIN antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for NOSTRIN. It may not necessarily be applicable to this product.
 NCBI GI #    284172481
 NCBI GeneID    115677
 NCBI Accession #    NP_001034813.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001039724.3 [Other Products]
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 UniProt Primary Accession #    Q8IVI9 [Other Products]
 UniProt Secondary Accession #    Q27HG3; Q53S62; Q96CJ9; A8K2I9; B3KSF5; E7EPT9 [Other Products]
 UniProt Related Accession #    Q8IVI9 [Other Products]
 Molecular Weight    64,364 Da
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 NCBI Official Full Name    nostrin isoform 2
 NCBI Official Synonym Full Names    nitric oxide synthase trafficking
 NCBI Official Symbol    NOSTRIN [Similar Products]
 NCBI Official Synonym Symbols   
DaIP2
[Similar Products]
 NCBI Protein Information    nostrin
 UniProt Protein Name    Nostrin
 UniProt Synonym Protein Names   
BM247 homolog; Nitric oxide synthase traffic inducer; Nitric oxide synthase trafficker; eNOS-trafficking inducer
 Protein Family    Nostrin
 UniProt Gene Name    NOSTRIN [Similar Products]
 UniProt Entry Name    NOSTN_HUMAN
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 NCBI Summary for NOSTRIN    Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004]
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 UniProt Comments for NOSTRIN    NOSTRIN: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: cytoskeleton; nucleus; plasma membrane

Molecular Function: DNA binding; protein binding

Biological Process: endocytosis; negative regulation of transcription, DNA-dependent; nitric oxide metabolic process; regulation of nitric-oxide synthase activity; signal transduction
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 Research Articles on NOSTRIN    1. no significant difference in serum level associated with preeclampsia or intrauterine growth restriction
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-NOSTRIN antibodyDiseases associated with anti-NOSTRIN antibody
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nitric Oxide Pathway antibodies  Metabolism Of Nitric Oxide Pathway Diagram
 NOSTRIN Mediated ENOS Trafficking Pathway antibodies  NOSTRIN Mediated ENOS Trafficking Pathway Diagram
 ENOS Activation And Regulation Pathway antibodies  ENOS Activation And Regulation Pathway Diagram
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >5 publications with NOSTRIN and Hypertension
 Cardiovascular Diseases Antibodies  >4 publications with NOSTRIN and Cardiovascular Diseases
 Inflammation Antibodies  >4 publications with NOSTRIN and Inflammation
 Proteinuria Antibodies  >2 publications with NOSTRIN and Proteinuria
 Necrosis Antibodies  >2 publications with NOSTRIN and Necrosis
 Pneumonia Antibodies  >1 publications with NOSTRIN and Pneumonia
 Death Antibodies  >1 publications with NOSTRIN and Death
 Infertility, Male Antibodies  >1 publications with NOSTRIN and Infertility, Male
 Atherosclerosis Antibodies  >1 publications with NOSTRIN and Atherosclerosis
 Fetal Death Antibodies  >1 publications with NOSTRIN and Fetal Death
Organs/Tissues associated with anti-NOSTRIN antibody
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >13 publications with NOSTRIN and Vascular
 Embryonic Tissue Antibodies  >3 publications with NOSTRIN and Embryonic Tissue
 Lung Antibodies  >3 publications with NOSTRIN and Lung
 Placenta Antibodies  >3 publications with NOSTRIN and Placenta
 Liver Antibodies  >2 publications with NOSTRIN and Liver
 Kidney Antibodies  >2 publications with NOSTRIN and Kidney
 Testis Antibodies  >2 publications with NOSTRIN and Testis
 Brain Antibodies  >2 publications with NOSTRIN and Brain
 Muscle Antibodies  >1 publications with NOSTRIN and Muscle
 Uncharacterized Tissue Antibodies  >1 publications with NOSTRIN and Uncharacterized Tissue
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