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anti-NPFFR1 antibody :: Rabbit anti-Human NPFFR1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9201462
Western Blot (WB)
Unit / Price
0.08 mL  /  $150 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NPFFR1, Polyclonal Antibody

★Popular Item★
 Also Known As   

NPFFR1 Antibody (C-term)

 Product Synonym Names    Neuropeptide FF receptor 1; G-protein coupled receptor 147; RFamide-related peptide receptor OT7T022; NPFFR1; GPR147; NPFF1
 Product Gene Name   

anti-NPFFR1 antibody

[Similar Products]
 Antibody/Peptide Pairs    NPFFR1 peptide (MBS9220554) is used for blocking the activity of NPFFR1 antibody (MBS9201462)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    337-366
 OMIM    607448
 3D Structure    ModBase 3D Structure for Q9GZQ6
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 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    This NPFFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human NPFFR1.
 Purity/Purification    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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 Calculated MW    47819
 Cellular location    Cell membrane; Multi-pass membraneprotein.
 Function    Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
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 Preparation and Storage    Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-NPFFR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NPFFR1 antibody

   Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
 Product Categories/Family for anti-NPFFR1 antibody    Neuroscience; Signal Transduction; GPCR Antibodies
 Applications Tested/Suitable for anti-NPFFR1 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-NPFFR1 antibody    WB~~1:1000
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 Western Blot (WB) of anti-NPFFR1 antibody    NPFFR1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NPFFR1 antibody detected the NPFFR1 protein (arrow).
anti-NPFFR1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for NPFFR1. It may not necessarily be applicable to this product.
 NCBI GI #    11545887
 NCBI GeneID    64106
 NCBI Accession #    NP_071429.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022146.4 [Other Products]
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 UniProt Primary Accession #    Q9GZQ6 [Other Products]
 UniProt Secondary Accession #    Q8NGR0; Q96RN3; A2RRF0 [Other Products]
 UniProt Related Accession #    Q9GZQ6 [Other Products]
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 NCBI Official Full Name    neuropeptide FF receptor 1
 NCBI Official Synonym Full Names    neuropeptide FF receptor 1
 NCBI Official Symbol    NPFFR1 [Similar Products]
 NCBI Official Synonym Symbols   
NPFF1; GPR147; NPFF1R1; OT7T022
[Similar Products]
 NCBI Protein Information    neuropeptide FF receptor 1
 UniProt Protein Name    Neuropeptide FF receptor 1
 UniProt Synonym Protein Names   
G-protein coupled receptor 147; RFamide-related peptide receptor OT7T022
 Protein Family    Neuropeptide FF receptor
 UniProt Gene Name    NPFFR1 [Similar Products]
 UniProt Synonym Gene Names    GPR147; NPFF1 [Similar Products]
 UniProt Entry Name    NPFF1_HUMAN
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 UniProt Comments for NPFFR1    NPFFR1: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10q21-q22

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; neuropeptide receptor activity; peptide binding

Biological Process: synaptic transmission; neuropeptide signaling pathway; cellular response to hormone stimulus
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Product References and Citations for anti-NPFFR1 antibody

   Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ubuka, T., et al. PLoS ONE 4 (12), E8400 (2009) :
Dowal, L., et al. J. Biol. Chem. 281(33):23999-24014(2006)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Bonini, J.A., et al. J. Biol. Chem. 275(50):39324-39331(2000)
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 Research Articles on NPFFR1    1. RFRP-3/GPR147 may play secondary, modulatory roles on the regulation of pubertal development; a restraining modulatory effect of the NPVF p.I71_K72 variant on the activation of the gonadotrophic axis cannot be ruled out
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NPFFR1 antibodyOrgans/Tissues associated with anti-NPFFR1 antibody
 Reference Product  PubMed Publications
 NPFF antibody  >2 publications with NPFFR1 and NPFF
 KISS1R antibody  >1 publications with NPFFR1 and KISS1R
 QRFPR antibody  >1 publications with NPFFR1 and QRFPR
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with NPFFR1 and Brain
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