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anti-NPY2R antibody :: Rabbit NPY2R Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS241663
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NPY2R, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal (IgG) to Human NPY2R

 Product Synonym Names    Anti-NPY2R Antibody (aa350-400) IHC-plus; NPY2R; Neuropeptide Y2 receptor; NPY-Y2 receptor; Neuropeptide Y receptor Y2; Neuropeptide y-y2; NPY2-R; Type 2 neuropeptide y receptor; Hypothalamic Y2 receptor; Neuropeptide Y receptor type 2; Peptide yy y2 receptor; Y2 receptor; Human NPY2R
 Product Gene Name   

anti-NPY2R antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    162642
 3D Structure    ModBase 3D Structure for P49146
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Dog, Human, Monkey, Mouse
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 Specificity    A portion of amino acids 350-400 of human NPY2-R
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.2% gelatin, 0.05% sodium azide.
 Concentration    0.5 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human NPY2R.
 Immunogen Type    Synthetic peptide
 Immunogen    NPY2R antibody was raised against synthetic peptide from human NPY2R.
 Antigen Modification    aa350-400
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 Preparation and Storage    Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
 Other Notes    Small volumes of anti-NPY2R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NPY2R antibody

   NPY2R belongs to the Neuropeptide Receptor GPCR family.
 Product Categories/Family for anti-NPY2R antibody    Family: GPCR
Subfamily: Neuropeptide
 Applications Tested/Suitable for anti-NPY2R antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-NPY2R antibody    IHC-P (10 ug/ml), WB (1 - 3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-NPY2R antibody    Anti-NPY2R antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-NPY2R antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-NPY2R antibody    Western blot of NPY2-R in the 1) absence and 2) presence of immunizing peptide in human kidney lysate using antibody at 0.05 ug/ml.
anti-NPY2R antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for NPY2R. It may not necessarily be applicable to this product.
 NCBI GI #    4505447
 NCBI GeneID    4887
 NCBI Accession #    NP_000901.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000910.3 [Other Products]
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 UniProt Primary Accession #    P49146 [Other Products]
 UniProt Secondary Accession #    Q13281; Q13457; Q4W5G7; Q6AZZ6; Q9UE67 [Other Products]
 UniProt Related Accession #    P49146 [Other Products]
 Molecular Weight    42,731 Da
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 NCBI Official Full Name    neuropeptide Y receptor type 2
 NCBI Official Synonym Full Names    neuropeptide Y receptor Y2
 NCBI Official Symbol    NPY2R [Similar Products]
 NCBI Official Synonym Symbols   
NPY2-R
[Similar Products]
 NCBI Protein Information    neuropeptide Y receptor type 2; NPY-Y2 receptor
 UniProt Protein Name    Neuropeptide Y receptor type 2
 UniProt Synonym Protein Names   
NPY-Y2 receptor; Y2 receptor
 Protein Family    Neuropeptide Y receptor
 UniProt Gene Name    NPY2R [Similar Products]
 UniProt Synonym Gene Names    NPY2-R; Y2 receptor [Similar Products]
 UniProt Entry Name    NPY2R_HUMAN
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 UniProt Comments for NPY2R    NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 4q31

Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane

Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity

Biological Process: positive regulation of dopamine secretion; secretion; behavioral fear response; positive regulation of cell adhesion; negative regulation of synaptic transmission, glutamatergic; locomotory behavior; positive regulation of peptide secretion; elevation of cytosolic calcium ion concentration; negative regulation of cAMP biosynthetic process; neuropeptide signaling pathway; negative regulation of secretion; regulation of sensory perception of pain; positive regulation of smooth muscle contraction; G-protein signaling, adenylate cyclase inhibiting pathway; nitric oxide mediated signal transduction; positive regulation of circadian sleep/wake cycle, non-REM sleep; negative regulation of neurological process
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 Research Articles on NPY2R    1. Data indicate modest association of the age at onset (AO) with two neuropeptide Y (NPY) promoter variations and a highly significant association with NPY receptor NPY2R promoter single nucleotide polymorphism (SNP rs2234759).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NPY2R antibodyPathways associated with anti-NPY2R antibody
 Reference Product  PubMed Publications
 NPY antibody  >18 publications with NPY2R and NPY
 NPY5R antibody  >12 publications with NPY2R and NPY5R
 PYY antibody  >6 publications with NPY2R and PYY
 PPY antibody  >2 publications with NPY2R and PPY
 POMC antibody  >1 publications with NPY2R and POMC
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-NPY2R antibodyOrgans/Tissues associated with anti-NPY2R antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >3 publications with NPY2R and Brain Diseases
 Mental Disorders Antibodies  >3 publications with NPY2R and Mental Disorders
 Hypertension Antibodies  >2 publications with NPY2R and Hypertension
 Abnormalities, Multiple Antibodies  >2 publications with NPY2R and Abnormalities, Multiple
 Alcoholism Antibodies  >2 publications with NPY2R and Alcoholism
 Cardiomegaly Antibodies  >1 publications with NPY2R and Cardiomegaly
 Hypertrophy Antibodies  >1 publications with NPY2R and Hypertrophy
 Neurobehavioral Manifestations Antibodies  >1 publications with NPY2R and Neurobehavioral Manifestations
 Epilepsy Antibodies  >1 publications with NPY2R and Epilepsy
 Edema Antibodies  >1 publications with NPY2R and Edema
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with NPY2R and Brain
 Nerve Antibodies  >2 publications with NPY2R and Nerve
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