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anti-nr2B antibody :: Rabbit NR2B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS626809 anti-nr2B antibody
Unit / Price
0.05 mg  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NR2B, Polyclonal Antibody

★Popular Item★
 Also Known As   

NR2B, phosphorylated (Tyr1474) (NMDA R2b, NMDAR2B, N-methyl-D-aspartate Receptor Subunit 3, GRIN2B, Glutamate [NMDA] Receptor Subunit epsilon-2, NR2B, N-methyl-D-aspartate Receptor Subunit 2B, NR3)

 Product Synonym Names    Anti -NR2B, phosphorylated (Tyr1474) (NMDA R2b, NMDAR2B, N-methyl-D-aspartate Receptor Subunit 3, GRIN2B, Glutamate [NMDA] Receptor Subunit epsilon-2, NR2B, N-methyl-D-aspartate Receptor Subunit 2B, NR3)
 Product Gene Name   

anti-nr2B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for B5QTB1
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Monkey, Mouse, Rat
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 Specificity    Recognizes endogenous levels of human NR2B when phosphorylated at tyrosine 1474. Species Crossreactivity: mouse and rat
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
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 Immunogen    Synthetic phosphopeptide corresponding to human NMDAR2B around the phosphorylation site of Tyr1474 (H-V-YP-E-K).
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-nr2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-nr2B antibody

   NMDA receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B or NR2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA). Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease, epilepsy and ischemic neuronal cell death.
 Product Categories/Family for anti-nr2B antibody    Antibodies; Abs to Ion Channel
 Applications Tested/Suitable for anti-nr2B antibody   

Immunofluorescence (IF)

 Application Notes for anti-nr2B antibody    Suitable for use in Immunofluorescence.
Dilution: Immunofluorescence: 1:100-1:200
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NCBI/Uniprot data below describe general gene information for nr2B. It may not necessarily be applicable to this product.
 NCBI GI #    205362475
 NCBI Accession #    CAP08277.1 [Other Products]
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 UniProt Primary Accession #    B5QTB1 [Other Products]
 Molecular Weight    35,476 Da [Similar Products]
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 NCBI Official Full Name    N-methyl D-aspartate receptor subunit 2B
 UniProt Protein Name    N-methyl D-aspartate receptor subunit 2B
 UniProt Gene Name    nr2B [Similar Products]
 UniProt Entry Name    B5QTB1_9TELE
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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