NP_055064.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 43-45 kDa Predicted: 45 kDa
NCBI Official Full Name
photoreceptor-specific nuclear receptor isoform b
NCBI Official Synonym Full Names
nuclear receptor subfamily 2 group E member 3
NCBI Protein Information
photoreceptor-specific nuclear receptor
UniProt Protein Name
Photoreceptor-specific nuclear receptor
UniProt Synonym Protein Names
Nuclear receptor subfamily 2 group E member 3; Retina-specific nuclear receptor
UniProt Synonym Gene Names
NCBI Summary for NR2E3
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for NR2E3
Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
Research Articles on NR2E3
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Products associated with anti-NR2E3 antibody
Pathways associated with anti-NR2E3 antibody
Diseases associated with anti-NR2E3 antibody
Organs/Tissues associated with anti-NR2E3 antibody
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