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anti-NR2F2 antibody :: NR2F2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8216179
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NR2F2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-NR2F2 Antibody

 Product Synonym Names    ARP1; TFCOUP2; COUP transcription factor 2; COUP-TF2; Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2
 Product Gene Name   

anti-NR2F2 antibody

[Similar Products]
 Antibody/Peptide Pairs    NR2F2 peptide (MBS8212016) is used for blocking the activity of NR2F2 antibody (MBS8216179)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    107773
 3D Structure    ModBase 3D Structure for P24468
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 Clonality    Polyclonal
 Species Reactivity    Human, Mouse, Rat, Bovine, Dog, Porcine
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 Specificity    Recognizes endogenous levels of NR2F2 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Source    Rabbit
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NR2F2. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-NR2F2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NR2F2 antibody

   Rabbit polyclonal antibody to NR2F2
 Applications Tested/Suitable for anti-NR2F2 antibody   

Western Blot (WB),Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

 Application Notes for anti-NR2F2 antibody    WB (1/500 - 1/1000), IHC (1/100 - 1/200), IF/ICC (1/100 - 1/500)
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 Western Blot (WB) of anti-NR2F2 antibody    Western blot analysis of NR2F2 expression in HepG2 (A), HeLa (B) whole cell lysates.
anti-NR2F2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-NR2F2 antibody    Immunohistochemical analysis of NR2F2 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-NR2F2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-NR2F2 antibody    Immunofluorescent analysis of NR2F2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 degree C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
anti-NR2F2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for NR2F2. It may not necessarily be applicable to this product.
 NCBI GI #    223555949
 NCBI GeneID    7026
 NCBI Accession #    NP_001138627.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145155.1 [Other Products]
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 UniProt Primary Accession #    P24468 [Other Products]
 UniProt Secondary Accession #    Q03754; Q3KQR7; B4DQJ2; B6ZGU1 [Other Products]
 UniProt Related Accession #    P24468 [Other Products]
 Molecular Weight    29,163 Da
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 NCBI Official Full Name    COUP transcription factor 2 isoform b
 NCBI Official Synonym Full Names    nuclear receptor subfamily 2, group F, member 2
 NCBI Official Symbol    NR2F2 [Similar Products]
 NCBI Official Synonym Symbols   
ARP1; CHTD4; NF-E3; NR2F1; SVP40; COUPTFB; TFCOUP2; COUPTFII
[Similar Products]
 NCBI Protein Information    COUP transcription factor 2
 UniProt Protein Name    COUP transcription factor 2
 UniProt Synonym Protein Names   
Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2
 Protein Family    COUP transcription factor
 UniProt Gene Name    NR2F2 [Similar Products]
 UniProt Synonym Gene Names    ARP1; TFCOUP2; COUP-TF2; ARP-1; COUP-TF II [Similar Products]
 UniProt Entry Name    COT2_HUMAN
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 NCBI Summary for NR2F2    This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
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 UniProt Comments for NR2F2    NR2F2: Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. Interacts with SQSTM1. Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2. Ubiquitous. Belongs to the nuclear hormone receptor family. NR2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Nuclear receptor

Chromosomal Location of Human Ortholog: 15q26

Cellular Component: nucleus

Molecular Function: ligand-dependent nuclear receptor activity; protein binding; protein homodimerization activity; retinoic acid binding; zinc ion binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription corepressor activity; transcription factor activity

Biological Process: limb development; skeletal muscle development; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; neuron migration; negative regulation of cyclin-dependent protein kinase activity; negative regulation of transcription from RNA polymerase II promoter; signal transduction; response to estradiol stimulus; regulation of transcription from RNA polymerase II promoter; anterior/posterior pattern formation; fertilization; negative regulation of endothelial cell proliferation; forebrain development; blood vessel morphogenesis; steroid hormone mediated signaling; lipid metabolic process; negative regulation of transcription, DNA-dependent; radial pattern formation; maternal placenta development

Disease: Congenital Heart Defects, Multiple Types, 4
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 Research Articles on NR2F2    1. TGF-beta inhibited the expression of NR2F2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NR2F2 antibodyPathways associated with anti-NR2F2 antibody
 Reference Product  PubMed Publications
 APOB antibody  >5 publications with NR2F2 and APOB
 DR1 antibody  >5 publications with NR2F2 and DR1
 PAX6 antibody  >4 publications with NR2F2 and PAX6
 SOX9 antibody  >3 publications with NR2F2 and SOX9
 LCK antibody  >1 publications with NR2F2 and LCK
 KLF4 antibody  >1 publications with NR2F2 and KLF4
 PCK2 antibody  >1 publications with NR2F2 and PCK2
 NRP2 antibody  >1 publications with NR2F2 and NRP2
 RERE antibody  >1 publications with NR2F2 and RERE
 BCL11A antibody  >1 publications with NR2F2 and BCL11A
 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
 Regulation Of Telomerase Pathway antibodies  Regulation Of Telomerase Pathway Diagram
 Transcriptional Regulation Of White Adipocyte Differentiation Pathway antibodies  Transcriptional Regulation Of White Adipocyte Differentiation Pathway Diagram
Diseases associated with anti-NR2F2 antibodyOrgans/Tissues associated with anti-NR2F2 antibody
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >10 publications with NR2F2 and Adenocarcinoma
 Heart Diseases Antibodies  >7 publications with NR2F2 and Heart Diseases
 Neoplasm Metastasis Antibodies  >6 publications with NR2F2 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >6 publications with NR2F2 and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >6 publications with NR2F2 and Cell Transformation, Neoplastic
 Hernia, Diaphragmatic Antibodies  >6 publications with NR2F2 and Hernia, Diaphragmatic
 Carcinoma, Hepatocellular Antibodies  >5 publications with NR2F2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >5 publications with NR2F2 and Liver Neoplasms
 Liver Diseases Antibodies  >4 publications with NR2F2 and Liver Diseases
 Infertility, Male Antibodies  >3 publications with NR2F2 and Infertility, Male
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >37 publications with NR2F2 and Liver
 Vascular Antibodies  >23 publications with NR2F2 and Vascular
 Thyroid Antibodies  >23 publications with NR2F2 and Thyroid
 Brain Antibodies  >22 publications with NR2F2 and Brain
 Muscle Antibodies  >21 publications with NR2F2 and Muscle
 Embryonic Tissue Antibodies  >17 publications with NR2F2 and Embryonic Tissue
 Ear Antibodies  >16 publications with NR2F2 and Ear
 Heart Antibodies  >15 publications with NR2F2 and Heart
 Lung Antibodies  >11 publications with NR2F2 and Lung
 Bone Antibodies  >9 publications with NR2F2 and Bone
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