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anti-NR5A2 antibody :: Rabbit anti-Human, Mouse NR5A2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7048770
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NR5A2, Polyclonal Antibody

★Popular Item★
 Also Known As   

NR5A2 Antibody

 Product Synonym Names    Nuclear receptor subfamily 5 group A member 2; Alpha-1-fetoprotein transcription factor; B1-binding factor; hB1F; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1; LRH-1; NR5A2; B1F; CPF; FTF
 Product Gene Name   

anti-NR5A2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    U80251 mRNA
 3D Structure    ModBase 3D Structure for O00482
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Nuclear receptor subfamily 5 group A member 2 protein (182-291AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133844 / sc-21132 / sc-21133 / sc-25389 / sc-5993 / sc-5995 / sc-5997 / sc-5998
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-NR5A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NR5A2 antibody

   Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
 Applications Tested/Suitable for anti-NR5A2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-NR5A2 antibody    WB: 1: 500-1: 5000
IHC: 1: 20-1: 200
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 Western Blot (WB) of anti-NR5A2 antibody    Western Blot
Positive WB detected in: Hela whole cell lysate,PC3 whole cell lysate,HepG2 whole cell lysate,Mouse kidney tissue,Mouse brain tissue
All lanes: NR5A2 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 62,57,43,54 KDa
Observed band size: 62,54 KDa

anti-NR5A2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-NR5A2 antibody    Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7048770 at dilution of 1:100
anti-NR5A2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-NR5A2 antibody    Immunohistochemistry of paraffin-embedded human glioma cancer using MBS7048770 at dilution of 1:100
anti-NR5A2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for NR5A2. It may not necessarily be applicable to this product.
 NCBI GI #    451172094
 NCBI GeneID    2494
 NCBI Accession #    NP_001263393.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001276464.1 [Other Products]
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 UniProt Primary Accession #    O00482 [Other Products]
 UniProt Secondary Accession #    O95642; Q147U3; B4E2P3 [Other Products]
 UniProt Related Accession #    O00482 [Other Products]
 Molecular Weight    53,657 Da
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 NCBI Official Full Name    nuclear receptor subfamily 5 group A member 2 isoform 3
 NCBI Official Synonym Full Names    nuclear receptor subfamily 5 group A member 2
 NCBI Official Symbol    NR5A2 [Similar Products]
 NCBI Official Synonym Symbols   
B1F; CPF; FTF; B1F2; LRH1; LRH-1; FTZ-F1; hB1F-2; FTZ-F1beta
[Similar Products]
 NCBI Protein Information    nuclear receptor subfamily 5 group A member 2
 UniProt Protein Name    Nuclear receptor subfamily 5 group A member 2
 UniProt Synonym Protein Names   
Alpha-1-fetoprotein transcription factor; B1-binding factor; hB1F; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1; LRH-1
 Protein Family    Nuclear receptor subfamily
 UniProt Gene Name    NR5A2 [Similar Products]
 UniProt Synonym Gene Names    B1F; CPF; FTF; hB1F; LRH-1 [Similar Products]
 UniProt Entry Name    NR5A2_HUMAN
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 NCBI Summary for NR5A2    The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. [provided by RefSeq, Jun 2016]
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 UniProt Comments for NR5A2    Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
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 Research Articles on NR5A2    1. demonstrate aberrant expressions of SF-1 and LRH-1 in endometriotic granulosa-lutein cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NR5A2 antibodyPathways associated with anti-NR5A2 antibody
 Reference Product  PubMed Publications
 CYP19A1 antibody  >45 publications with NR5A2 and CYP19A1
 STAR antibody  >17 publications with NR5A2 and STAR
 CYP7A1 antibody  >15 publications with NR5A2 and CYP7A1
 CTNNB1 antibody  >14 publications with NR5A2 and CTNNB1
 NR0B2 antibody  >9 publications with NR5A2 and NR0B2
 HSD3B2 antibody  >7 publications with NR5A2 and HSD3B2
 ABCB11 antibody  >2 publications with NR5A2 and ABCB11
 GPS2 antibody  >1 publications with NR5A2 and GPS2
 NCOA3 antibody  >1 publications with NR5A2 and NCOA3
 EDF1 antibody  >1 publications with NR5A2 and EDF1
 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
 Regulation Of Beta-cell Development Pathway antibodies  Regulation Of Beta-cell Development Pathway Diagram
 Regulation Of Gene Expression In Early Pancreatic Precursor Cells Pathway antibodies  Regulation Of Gene Expression In Early Pancreatic Precursor Cells Pathway Diagram
Diseases associated with anti-NR5A2 antibodyOrgans/Tissues associated with anti-NR5A2 antibody
 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >45 publications with NR5A2 and Liver Neoplasms
 Liver Diseases Antibodies  >41 publications with NR5A2 and Liver Diseases
 Adenocarcinoma Antibodies  >26 publications with NR5A2 and Adenocarcinoma
 Breast Neoplasms Antibodies  >21 publications with NR5A2 and Breast Neoplasms
 Pancreatic Neoplasms Antibodies  >20 publications with NR5A2 and Pancreatic Neoplasms
 Inflammation Antibodies  >15 publications with NR5A2 and Inflammation
 Fatty Liver Antibodies  >14 publications with NR5A2 and Fatty Liver
 Infertility, Female Antibodies  >11 publications with NR5A2 and Infertility, Female
 Carcinoma, Hepatocellular Antibodies  >10 publications with NR5A2 and Carcinoma, Hepatocellular
 Disease Models, Animal Antibodies  >8 publications with NR5A2 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >241 publications with NR5A2 and Liver
 Pancreas Antibodies  >29 publications with NR5A2 and Pancreas
 Intestine Antibodies  >28 publications with NR5A2 and Intestine
 Testis Antibodies  >27 publications with NR5A2 and Testis
 Embryonic Tissue Antibodies  >23 publications with NR5A2 and Embryonic Tissue
 Brain Antibodies  >21 publications with NR5A2 and Brain
 Adrenal Gland Antibodies  >13 publications with NR5A2 and Adrenal Gland
 Kidney Antibodies  >8 publications with NR5A2 and Kidney
 Lung Antibodies  >6 publications with NR5A2 and Lung
 Muscle Antibodies  >6 publications with NR5A2 and Muscle
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