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anti-NUDT11 antibody :: Rabbit anti-Human NUDT11 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1494657
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NUDT11, Polyclonal Antibody

★Popular Item★
 Also Known As   

NUDT11 Antibody

 Product Synonym Names    Diphosphoinositol polyphosphate phosphohydrolase 3-beta (EC:3.6.1.52); DIPP-3-beta; DIPP3-beta; hDIPP3beta; NUDT11; APS1; DIPP3B; Diadenosine 5'; 5'''-P1; P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming) (EC:3.6.1.60); Nucleoside diphosphate-linked moiety X motif 11; Nudix motif 11; hAps1
 Product Gene Name   

anti-NUDT11 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300528
 3D Structure    ModBase 3D Structure for Q96G61
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Diphosphoinositol polyphosphate phosphohydrolase 3-beta protein
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-NUDT11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NUDT11 antibody

   Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
 Applications Tested/Suitable for anti-NUDT11 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-NUDT11 antibody    Recommended dilution: WB:1:500-2000
IHC:1:20-1:200
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 Western Blot (WB) of anti-NUDT11 antibody    Western blot
All lanes: NUDT11 antibody at 2ug/ml+ U251 whole cell lysate
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa

anti-NUDT11 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-NUDT11 antibody    Immunohistochemistry of paraffin-embedded human testis tissue using MBS1494657 at dilution of 1:100
anti-NUDT11 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for NUDT11. It may not necessarily be applicable to this product.
 NCBI GI #    37221177
 NCBI GeneID    55190
 NCBI Accession #    NP_060629.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_018159.3 [Other Products]
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 UniProt Primary Accession #    Q96G61 [Other Products]
 UniProt Secondary Accession #    Q9NVN0 [Other Products]
 UniProt Related Accession #    Q96G61 [Other Products]
 Molecular Weight    18,559 Da
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 NCBI Official Full Name    diphosphoinositol polyphosphate phosphohydrolase 3-beta
 NCBI Official Synonym Full Names    nudix hydrolase 11
 NCBI Official Symbol    NUDT11 [Similar Products]
 NCBI Official Synonym Symbols   
APS1; ASP1; DIPP3b; DIPP3beta; hDIPP3beta
[Similar Products]
 NCBI Protein Information    diphosphoinositol polyphosphate phosphohydrolase 3-beta
 UniProt Protein Name    Diphosphoinositol polyphosphate phosphohydrolase 3-beta
 UniProt Synonym Protein Names   
Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming) (EC:3.6.1.60
 Protein Family    Nudix hydrolase
 UniProt Gene Name    NUDT11 [Similar Products]
 UniProt Synonym Gene Names    APS1; DIPP3B; Nudix motif 11 [Similar Products]
 UniProt Entry Name    NUD11_HUMAN
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 NCBI Summary for NUDT11    NUDT11 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 [PubMed 12105228]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for NUDT11    NUDT11: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Belongs to the Nudix hydrolase family. DIPP subfamily.

Protein type: EC 3.6.1.52; Hydrolase; EC 3.6.1.60

Chromosomal Location of Human Ortholog: Xp11.22

Cellular Component: cytosol; intracellular

Molecular Function: diphosphoinositol-polyphosphate diphosphatase activity; metal ion binding

Biological Process: inositol phosphate metabolic process
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 Research Articles on NUDT11    1. NUDT11, HNF1B, and SLC22A3 genes have roles in prostate cancer pathogenesis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-NUDT11 antibodyDiseases associated with anti-NUDT11 antibody
 Products by Pathway  Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Synthesis Of Pyrophosphates In The Cytosol Pathway antibodies  Synthesis Of Pyrophosphates In The Cytosol Pathway Diagram
 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >3 publications with NUDT11 and Prostatic Neoplasms
Organs/Tissues associated with anti-NUDT11 antibody
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >4 publications with NUDT11 and Prostate
 Testis Antibodies  >2 publications with NUDT11 and Testis
 Brain Antibodies  >2 publications with NUDT11 and Brain
 Kidney Antibodies  >1 publications with NUDT11 and Kidney
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