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anti-NUDT16 antibody :: Rabbit NUDT16 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS839126 anti-NUDT16 antibody
Unit / Price
0.05 mL  /  $490 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NUDT16, Polyclonal Antibody

★Popular Item★
 Also Known As   

NUDT16 antibody

 Product Synonym Names    Polyclonal NUDT16; Anti-NUDT16; Nudix Type Motif 16; Nudt16; Flj31265
 Product Gene Name   

anti-NUDT16 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human. Other species are not tested.
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 Purity/Purification    NUDT16 antibody was purified by Antigen Affinity chromatography
 Form/Format    Liquid in PBS, pH 7.3, with 0.02% NaN3 and 50% glycerol.
 Concentration    0.34mg/ml (lot specific)
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 Biological Significance    NUDT16 is an RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner.
 Immunogen    NUDT16 antibody was raised in Rabbit using Human NUDT16 as the immunogen
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 Preparation and Storage    4C for shipping. Upon receipt store at -20C to -80C . Avoid repeat freeze-thaw cycles.
 Other Notes    Small volumes of anti-NUDT16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NUDT16 antibody

   Rabbit polyclonal NUDT16 antibody
 Product Categories/Family for anti-NUDT16 antibody    Proteases, Inhibitors, & Enzymes; Purified Polyclonal Antibodies
 Applications Tested/Suitable for anti-NUDT16 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-NUDT16 antibody    WB: 1:1,000-10,000
IP: 1:500-1:5,000
IHC and IF: 1:20-1:200
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NCBI/Uniprot data below describe general gene information for NUDT16. It may not necessarily be applicable to this product.
 NCBI GI #    73909074
 NCBI GeneID    131870
 NCBI Accession #    AAH31215.2 [Other Products]
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 UniProt Secondary Accession #    Q96N82; B4E3B4; E9PED4; F5GYJ1 [Other Products]
 UniProt Related Accession #    Q96DE0 [Other Products]
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 NCBI Official Full Name    NUDT16 protein
 NCBI Official Synonym Full Names    nudix (nucleoside diphosphate linked moiety X)-type motif 16
 NCBI Official Symbol    NUDT16 [Similar Products]
 NCBI Protein Information    U8 snoRNA-decapping enzyme
 UniProt Protein Name    U8 snoRNA-decapping enzyme
 UniProt Synonym Protein Names   
IDP phosphatase (EC:3.6.1.-); IDPase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; Nudix motif 16; U8 snoRNA-binding protein H29K; m7GpppN-mRNA hydrolase
 Protein Family    Nudix hydrolase
 UniProt Gene Name    NUDT16 [Similar Products]
 UniProt Synonym Gene Names    IDPase; Nudix motif 16 [Similar Products]
 UniProt Entry Name    NUD16_HUMAN
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 UniProt Comments for NUDT16    NUDT16: RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro). Belongs to the Nudix hydrolase family.

Protein type: EC 3.6.1.62; Nucleolus; Hydrolase

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: mRNA binding; snoRNA binding; m7G(5')pppN diphosphatase activity; protein homodimerization activity; metalloexopeptidase activity; GTP binding; manganese ion binding; magnesium ion binding; cobalt ion binding

Biological Process: snoRNA catabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of cell proliferation; mRNA catabolic process; proteolysis; adenosine to inosine editing; IDP catabolic process
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 Research Articles on NUDT16    1. hNUDT16 can also actively cleave the mGDP cap from mRNAs in the presence of Mg(2)(+) or Mn(2)(+).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NUDT16 antibodyPathways associated with anti-NUDT16 antibody
 Reference Product  PubMed Publications
 ITPA antibody  >3 publications with NUDT16 and ITPA
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Phosphate Bond Hydrolysis By NUDT Proteins Pathway antibodies  Phosphate Bond Hydrolysis By NUDT Proteins Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
Organs/Tissues associated with anti-NUDT16 antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with NUDT16 and Embryonic Tissue
 Uterus Antibodies  >1 publications with NUDT16 and Uterus
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