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anti-NUF2 antibody :: Rabbit NUF2, NDC80 kinetochore complex component, homolog Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714241 anti-NUF2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NUF2, NDC80 kinetochore complex component, homolog, Polyclonal Antibody

 Also Known As   

Rabbit anti-human NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) polyclonal Antibody

 Product Synonym Names    NUF2; NDC80 kinetochore complex component; homolog (S. cerevisiae); NUF2; CDCA1; NUF2R
 Product Gene Name   

anti-NUF2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611772
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human NUF2
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-103429 / sc-98369
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-NUF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-NUF2 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for NUF2. It may not necessarily be applicable to this product.
 NCBI GI #    14250144
 NCBI GeneID    83540
 NCBI Accession #    AAH08489.1 [Other Products]
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 UniProt Secondary Accession #    Q8WU69; Q96HJ4; Q96Q78 [Other Products]
 UniProt Related Accession #    Q9BZD4 [Other Products]
 Molecular Weight    54,304 Da [Similar Products]
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 NCBI Official Full Name    NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
 NCBI Official Synonym Full Names    NUF2, NDC80 kinetochore complex component
 NCBI Official Symbol    NUF2 [Similar Products]
 NCBI Official Synonym Symbols   
CDCA1; CT106; NUF2R
[Similar Products]
 NCBI Protein Information    kinetochore protein Nuf2; hNuf2; hNuf2R; hsNuf2; cancer/testis antigen 106; cell division cycle associated 1; cell division cycle-associated protein 1; NUF2, NDC80 kinetochore complex component, homolog
 UniProt Protein Name    Kinetochore protein Nuf2
 UniProt Synonym Protein Names   
Cell division cycle-associated protein 1
 Protein Family    Kinetochore protein
 UniProt Gene Name    NUF2 [Similar Products]
 UniProt Synonym Gene Names    CDCA1; NUF2R; hNuf2; hNuf2R; hsNuf2 [Similar Products]
 UniProt Entry Name    NUF2_HUMAN
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 NCBI Summary for NUF2    This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NUF2    NUF2: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Belongs to the NUF2 family.

Protein type: DNA replication; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: membrane; nucleus; cytosol; chromosome, pericentric region

Molecular Function: protein binding

Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation
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 Research Articles on NUF2    1. These results suggest that CDCA1 could be a prognostic biomarker and a potential therapeutic target for colorectal cancers .
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NUF2 antibodyPathways associated with anti-NUF2 antibody
 Reference Product  PubMed Publications
 NDC80 antibody  >47 publications with NUF2 and NDC80
 SPC24 antibody  >19 publications with NUF2 and SPC24
 SPC25 antibody  >19 publications with NUF2 and SPC25
 BUB1 antibody  >10 publications with NUF2 and BUB1
 MIS12 antibody  >9 publications with NUF2 and MIS12
 AURKB antibody  >4 publications with NUF2 and AURKB
 CENPH antibody  >1 publications with NUF2 and CENPH
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 Mitotic Anaphase Pathway antibodies  Mitotic Anaphase Pathway Diagram
 Mitotic Metaphase And Anaphase Pathway antibodies  Mitotic Metaphase And Anaphase Pathway Diagram
 Mitotic Prometaphase Pathway antibodies  Mitotic Prometaphase Pathway Diagram
 Resolution Of Sister Chromatid Cohesion Pathway antibodies  Resolution Of Sister Chromatid Cohesion Pathway Diagram
 Separation Of Sister Chromatids Pathway antibodies  Separation Of Sister Chromatids Pathway Diagram
Diseases associated with anti-NUF2 antibodyOrgans/Tissues associated with anti-NUF2 antibody
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >3 publications with NUF2 and Lung Neoplasms
 Lung Diseases Antibodies  >2 publications with NUF2 and Lung Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with NUF2 and Carcinoma, Hepatocellular
 Prostatic Neoplasms Antibodies  >2 publications with NUF2 and Prostatic Neoplasms
 Hepatitis Antibodies  >1 publications with NUF2 and Hepatitis
 Anemia Antibodies  >1 publications with NUF2 and Anemia
 Ovarian Diseases Antibodies  >1 publications with NUF2 and Ovarian Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with NUF2 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >1 publications with NUF2 and Liver Diseases
 Precancerous Conditions Antibodies  >1 publications with NUF2 and Precancerous Conditions
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >5 publications with NUF2 and Testis
 Lung Antibodies  >3 publications with NUF2 and Lung
 Blood Antibodies  >3 publications with NUF2 and Blood
 Bone Antibodies  >2 publications with NUF2 and Bone
 Bone Marrow Antibodies  >2 publications with NUF2 and Bone Marrow
 Stomach Antibodies  >2 publications with NUF2 and Stomach
 Intestine Antibodies  >1 publications with NUF2 and Intestine
 Prostate Antibodies  >1 publications with NUF2 and Prostate
 Muscle Antibodies  >1 publications with NUF2 and Muscle
 Liver Antibodies  >1 publications with NUF2 and Liver
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