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anti-NTN1 antibody :: Rabbit Netrin-1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2537348
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Netrin-1 (NTN1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Netrin-1 Polyclonal Antibody

 Product Synonym Names    NTN1; NTN1L; Netrin-1; Epididymis tissue protein Li 131P
 Product Gene Name   

anti-NTN1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601614
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Monkey
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from the C-terminal region of human Netrin-1.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-NTN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-NTN1 antibody    Epigenetics
 Applications Tested/Suitable for anti-NTN1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-NTN1 antibody    WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-NTN1 antibody    Western Blot analysis of various cells using Netrin-1 Polyclonal Antibody at dilution of 1:1000.
anti-NTN1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for NTN1. It may not necessarily be applicable to this product.
 NCBI GI #    148613884
 NCBI GeneID    9423
 NCBI Accession #    NP_004813.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004822.2 [Other Products]
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 UniProt Secondary Accession #    E9KL51 [Other Products]
 UniProt Related Accession #    O95631 [Other Products]
 Molecular Weight    Calculated MW: 68
Observed MW: 75
[Similar Products]
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 NCBI Official Full Name    netrin-1
 NCBI Official Synonym Full Names    netrin 1
 NCBI Official Symbol    NTN1 [Similar Products]
 NCBI Official Synonym Symbols   
NTN1L
[Similar Products]
 NCBI Protein Information    netrin-1
 UniProt Protein Name    Netrin-1
 UniProt Synonym Protein Names   
Epididymis tissue protein Li 131P
 Protein Family    Netrin
 UniProt Gene Name    NTN1 [Similar Products]
 UniProt Synonym Gene Names    NTN1L [Similar Products]
 UniProt Entry Name    NET1_HUMAN
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 NCBI Summary for NTN1    Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NTN1    NTN1: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: basement membrane; cytoplasm; extracellular region

Molecular Function: protein binding

Biological Process: anterior/posterior axon guidance; apoptosis; axon guidance; Cdc42 protein signal transduction; cell-cell adhesion; establishment of nucleus localization; inner ear morphogenesis; negative regulation of axon extension; neuron migration; positive regulation of axon extension; positive regulation of cell proliferation; Ras protein signal transduction; regulation of cell migration; substrate-bound cell migration, cell extension
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 Research Articles on NTN1    1. Investigation of the mechanisms that trigger local translation revealed a role for calcium-dependent retrograde netrin-1/DCC receptor signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NTN1 antibodyPathways associated with anti-NTN1 antibody
 Reference Product  PubMed Publications
 DCC antibody  >8 publications with NTN1 and DCC
 UNC5B antibody  >6 publications with NTN1 and UNC5B
 UNC5C antibody  >2 publications with NTN1 and UNC5C
 UNC5A antibody  >1 publications with NTN1 and UNC5A
 NEO1 antibody  >1 publications with NTN1 and NEO1
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 DCC Mediated Attractive Signaling Pathway antibodies  DCC Mediated Attractive Signaling Pathway Diagram
 DSCAM Interactions Pathway antibodies  DSCAM Interactions Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Netrin Mediated Repulsion Signals Pathway antibodies  Netrin Mediated Repulsion Signals Pathway Diagram
 Netrin-1 Signaling Pathway antibodies  Netrin-1 Signaling Pathway Diagram
Diseases associated with anti-NTN1 antibodyOrgans/Tissues associated with anti-NTN1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >8 publications with NTN1 and Inflammation
 Congenital Abnormalities Antibodies  >3 publications with NTN1 and Congenital Abnormalities
 Abnormalities, Multiple Antibodies  >2 publications with NTN1 and Abnormalities, Multiple
 Disease Models, Animal Antibodies  >2 publications with NTN1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >2 publications with NTN1 and Nervous System Diseases
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with NTN1 and Prenatal Exposure Delayed Effects
 Cell Transformation, Neoplastic Antibodies  >1 publications with NTN1 and Cell Transformation, Neoplastic
 Liver Neoplasms Antibodies  >1 publications with NTN1 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with NTN1 and Neoplasm Metastasis
 Lung Neoplasms Antibodies  >1 publications with NTN1 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with NTN1 and Brain
 Embryonic Tissue Antibodies  >4 publications with NTN1 and Embryonic Tissue
 Muscle Antibodies  >3 publications with NTN1 and Muscle
 Eye Antibodies  >3 publications with NTN1 and Eye
 Connective Tissue Antibodies  >2 publications with NTN1 and Connective Tissue
 Lung Antibodies  >2 publications with NTN1 and Lung
 Ovary Antibodies  >1 publications with NTN1 and Ovary
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