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anti-Nmnat3 antibody :: Goat Nmnat3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422800
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Nmnat3, Polyclonal Antibody

 Also Known As   

Goat anti-Nmnat3 (mouse) Antibody

 Product Synonym Names    Nmnat3; nicotinamide nucleotide adenylyltransferase 3; 4933408N02Rik; MGC102340; PNAT3; NMN adenylyltransferase 3; OTTMUSP00000025890; OTTMUSP00000025891; naMN adenylyltransferase 1; nicotinamide mononucleotide adenylyltransferase 3; nicotinate-nucleotide; Nmnat3 antibody; nicotinamide nucleotide adenylyltransferase 3 antibody; 4933408N02Rik antibody; MGC102340 antibody; PNAT3 antibody; NMN adenylyltransferase 3 antibody; OTTMUSP00000025890 antibody; OTTMUSP00000025891 antibody; naMN adenylyltransferase 1 antibody; nicotinamide mononucleotide adenylyltransferase 3 antibody; nicotinate-nucleotide adenylyltransferase 1 antibody; 4933408N02Rik antibody; MGC102340 antibody; naMN adenylyltransferase 1 antibody; nicotinamide mononucleotide adenylyltransferase 3 antibody; nicotinamide nucleotide adenylyltransferase 3 antibody; nicotinate-nucleotide adenylyltransferase 1 antibody; NMN adenylyltransferase 3 antibody; OTTMUSP00000025890 antibody; OTTMUSP00000025891 antibody; PNAT3 antibody; Nmnat3 antibody; Nmnat3 (mouse)
 Product Gene Name   

anti-Nmnat3 antibody

[Similar Products]
 Antibody/Peptide Pairs    Nmnat3 peptide (MBS427500) is used for blocking the activity of Nmnat3 antibody (MBS422800)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KALGQGQSVK YLLPE
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Mouse; Expected from sequence similarity: Mouse
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-KALGQGQSVKYLLPE, from the internal region of the protein sequence according to NP_653116.1.
 Epitope    Internal region
 Note    This antibody is expected to recognize both reported isoforms (NP_835471.1; NP_001186976.1).
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-Nmnat3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Nmnat3 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-Nmnat3 antibody    Peptide ELISA: Antibody detection limit dilution 1: 64000.
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 Western Blot (WB) of anti-Nmnat3 antibody    (0.5ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-Nmnat3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for Nmnat3. It may not necessarily be applicable to this product.
 NCBI GI #    21362329
 NCBI GeneID    74080
 NCBI Accession #    NP_653116.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_144533.2 [Other Products]
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 UniProt Secondary Accession #    Q58E37 [Other Products]
 UniProt Related Accession #    Q99JR6 [Other Products]
 Molecular Weight    27,703 Da
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 NCBI Official Full Name    nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
 NCBI Official Synonym Full Names    nicotinamide nucleotide adenylyltransferase 3
 NCBI Official Symbol    Nmnat3 [Similar Products]
 NCBI Official Synonym Symbols   
PNAT3; 4933408N02Rik
[Similar Products]
 NCBI Protein Information    nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
 UniProt Protein Name    Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
 UniProt Synonym Protein Names   
Nicotinamide-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; Nicotinate-nucleotide adenylyltransferase 3; NaMN adenylyltransferase 3
 Protein Family    Nicotinamide/nicotinic acid mononucleotide adenylyltransferase
 UniProt Gene Name    Nmnat3 [Similar Products]
 UniProt Synonym Gene Names    NMN/NaMN adenylyltransferase 3; NMN adenylyltransferase 3; NaMN adenylyltransferase 3 [Similar Products]
 UniProt Entry Name    NMNA3_MOUSE
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 UniProt Comments for Nmnat3    NMNAT3: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury. Belongs to the eukaryotic NMN adenylyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Apoptosis; EC 2.7.7.18; Mitochondrial; Transferase; EC 2.7.7.1

Cellular Component: mitochondrion

Molecular Function: ATP binding; catalytic activity; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; nucleotide binding; nucleotidyltransferase activity; transferase activity

Biological Process: biosynthetic process; NAD biosynthetic process; pyridine nucleotide biosynthetic process; response to wounding
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 Research Articles on Nmnat3    1. Data indicate that nicotinamide mononucleotide adenylyltransferase 3 (Nmnat3)deficiency causes splenomegaly and hemolytic anemia in mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-Nmnat3 antibodyDiseases associated with anti-Nmnat3 antibody
 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 NAD Biosynthesis III Pathway antibodies  NAD Biosynthesis III Pathway Diagram
 NAD Salvage Pathway II antibodies  NAD Salvage Pathway II Diagram
 NAD Salvage Pathway III antibodies  NAD Salvage Pathway III Diagram
 Nicotinate And Nicotinamide Metabolism Pathway antibodies  Nicotinate And Nicotinamide Metabolism Pathway Diagram
 Nicotinate And Nicotinamide Metabolism Pathway antibodies  Nicotinate And Nicotinamide Metabolism Pathway Diagram
 Nicotinate Metabolism Pathway antibodies  Nicotinate Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with Nmnat3 and Necrosis
 Hypertrophy Antibodies  >1 publications with Nmnat3 and Hypertrophy
 Inflammation Antibodies  >1 publications with Nmnat3 and Inflammation
Organs/Tissues associated with anti-Nmnat3 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with Nmnat3 and Brain
 Eye Antibodies  >1 publications with Nmnat3 and Eye
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