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anti-OASIS antibody :: Goat OASIS / CREB3L1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS244171
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

OASIS / CREB3L1, Polyclonal Antibody

 Also Known As   

Goat Polyclonal to Human OASIS / CREB3L1

 Product Synonym Names    Anti-OASIS / CREB3L1 Antibody (C-Terminus) IHC-plus; CREB3L1; BBF-2 homolog; OASIS; Human OASIS; CREB3L1
 Product Gene Name   

anti-OASIS antibody

[Similar Products]
 Product Synonym Gene Name    CREB3L1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q96BA8
 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Gorilla, Human, Monkey
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 Specificity    Human CREB3L1.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
 Concentration    0.5 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide C-DFSHSKEWFHDRD from the C-terminus of human CREB3L1 (NP_443086.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Rat, Hamster, Elephant, Bovine, Bat, Pig (85%).
 Immunogen Type    Synthetic peptide
 Immunogen    OASIS / CREB3L1 antibody was raised against synthetic peptide C-DFSHSKEWFHDRD from the C-terminus of human CREB3L1 (NP_443086.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Rat, Hamster, Elephant, Bovine, Bat, Pig (85%).
 Antigen Modification    C-Terminus
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 Preparation and Storage    Store at -20 degree C. Minimize freezing and thawing.
 Other Notes    Small volumes of anti-OASIS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-OASIS antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

 Application Notes for anti-OASIS antibody    ELISA (1:32000), IHC-P (3.75 ug/ml), WB (1 - 3 ug/ml)
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 Immunohistochemistry (IHC) of anti-OASIS antibody    Anti-CREB3L1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
anti-OASIS antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-OASIS antibody    Anti-CREB3L1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
anti-OASIS antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-OASIS antibody    Approx. 60 kD band observed in lysates of cell line A549 (calculated MW of 57 kD according to NP_443086.1).
anti-OASIS antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for OASIS. It may not necessarily be applicable to this product.
 NCBI GI #    16418355
 NCBI GeneID    90993
 NCBI Accession #    NP_443086.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_052854.3 [Other Products]
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 UniProt Primary Accession #    Q96BA8 [Other Products]
 UniProt Secondary Accession #    Q8N2D5; Q96CP0 [Other Products]
 UniProt Related Accession #    Q96BA8 [Other Products]
 Molecular Weight    47,783 Da
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 NCBI Official Full Name    cyclic AMP-responsive element-binding protein 3-like protein 1
 NCBI Official Synonym Full Names    cAMP responsive element binding protein 3-like 1
 NCBI Official Symbol    CREB3L1 [Similar Products]
 NCBI Official Synonym Symbols   
OASIS
[Similar Products]
 NCBI Protein Information    cyclic AMP-responsive element-binding protein 3-like protein 1; BBF-2 homolog; old astrocyte specifically-induced substance; cAMP-responsive element-binding protein 3-like protein 1
 UniProt Protein Name    Cyclic AMP-responsive element-binding protein 3-like protein 1
 UniProt Synonym Protein Names   
Old astrocyte specifically-induced substance; OASIS
 UniProt Gene Name    CREB3L1 [Similar Products]
 UniProt Synonym Gene Names    OASIS; cAMP-responsive element-binding protein 3-like protein 1; OASIS [Similar Products]
 UniProt Entry Name    CR3L1_HUMAN
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 NCBI Summary for OASIS    The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements. [provided by RefSeq, Jun 2013]
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 UniProt Comments for OASIS    CREB3L1: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. Belongs to the bZIP family. ATF subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transcription factor

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleus

Molecular Function: sequence-specific DNA binding; chromatin binding

Biological Process: transcription, DNA-dependent; unfolded protein response; regulation of bone mineralization
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 Research Articles on OASIS    1. Case Report: low-grade fibromyxoid sarcoma of the kidney found to harbor the EWSR1-CREB3L1 gene fusion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-OASIS antibodyPathways associated with anti-OASIS antibody
 Reference Product  PubMed Publications
 CREB3L3 antibody  >3 publications with OASIS and CREB3L3
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Cholinergic Synapse Pathway antibodies  Cholinergic Synapse Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
Diseases associated with anti-OASIS antibodyOrgans/Tissues associated with anti-OASIS antibody
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >3 publications with OASIS and Disease Models, Animal
 Inflammation Antibodies  >3 publications with OASIS and Inflammation
 Neoplasm Metastasis Antibodies  >2 publications with OASIS and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >1 publications with OASIS and Cardiovascular Diseases
 Precancerous Conditions Antibodies  >1 publications with OASIS and Precancerous Conditions
 Lung Neoplasms Antibodies  >1 publications with OASIS and Lung Neoplasms
 Kidney Diseases Antibodies  >1 publications with OASIS and Kidney Diseases
 Fibrosis Antibodies  >1 publications with OASIS and Fibrosis
 Abnormalities, Drug-Induced Antibodies  >1 publications with OASIS and Abnormalities, Drug-Induced
 Uterine Cervical Neoplasms Antibodies  >1 publications with OASIS and Uterine Cervical Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >14 publications with OASIS and Bone
 Brain Antibodies  >8 publications with OASIS and Brain
 Connective Tissue Antibodies  >5 publications with OASIS and Connective Tissue
 Mouth Antibodies  >4 publications with OASIS and Mouth
 Embryonic Tissue Antibodies  >4 publications with OASIS and Embryonic Tissue
 Pancreas Antibodies  >4 publications with OASIS and Pancreas
 Kidney Antibodies  >2 publications with OASIS and Kidney
 Liver Antibodies  >2 publications with OASIS and Liver
 Intestine Antibodies  >2 publications with OASIS and Intestine
 Ovary Antibodies  >1 publications with OASIS and Ovary
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