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anti-OLFM1 antibody :: Rabbit anti-Human, Mouse OLFM1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7051068
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

OLFM1, Polyclonal Antibody

★Popular Item★
 Also Known As   

OLFM1 Antibody

 Product Synonym Names    Noelin; Neuronal olfactomedin-related ER localized protein; Olfactomedin-1; OLFM1; NOE1; NOEL1
 Product Gene Name   

anti-OLFM1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    D82343 mRNA
 3D Structure    ModBase 3D Structure for Q99784
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Noelin protein (374-441AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130179 / sc-165155
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-OLFM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-OLFM1 antibody

   Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli (By similarity).
 Applications Tested/Suitable for anti-OLFM1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-OLFM1 antibody    WB: 1: 500-1: 5000
IHC: 1: 20-1: 200
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 Western Blot (WB) of anti-OLFM1 antibody    Western Blot
Positive WB detected in: NIH/3T3 whole cell lysate,Mouse brain tissue
All lanes: OLFM1 antibody at 2.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 56,18,55,16,53 KDa
Observed band size: 56 KDa

anti-OLFM1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-OLFM1 antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7051068 at dilution of 1:100
anti-OLFM1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-OLFM1 antibody    Immunohistochemistry of paraffin-embedded human liver cancer using MBS7051068 at dilution of 1:100
anti-OLFM1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for OLFM1. It may not necessarily be applicable to this product.
 NCBI GI #    543871463
 NCBI GeneID    10439
 NCBI Accession #    NP_001269540.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001282611.1 [Other Products]
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 UniProt Primary Accession #    Q99784 [Other Products]
 UniProt Secondary Accession #    Q53XZ8; Q6IMJ4; Q6IMJ5; Q8N8R0; Q969S7; Q99452 [Other Products]
 UniProt Related Accession #    Q99784 [Other Products]
 Molecular Weight    52,815 Da
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 NCBI Official Full Name    noelin isoform 4
 NCBI Official Synonym Full Names    olfactomedin 1
 NCBI Official Symbol    OLFM1 [Similar Products]
 NCBI Official Synonym Symbols   
AMY; NOE1; OlfA; NOELIN1
[Similar Products]
 NCBI Protein Information    noelin
 UniProt Protein Name    Noelin
 UniProt Synonym Protein Names   
Neuronal olfactomedin-related ER localized protein; Olfactomedin-1
 Protein Family    Noelin
 UniProt Gene Name    OLFM1 [Similar Products]
 UniProt Synonym Gene Names    NOE1; NOEL1 [Similar Products]
 UniProt Entry Name    NOE1_HUMAN
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 NCBI Summary for OLFM1    This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for OLFM1    OLFM1: Seems to play an important role in regulating the production of neural crest cells by the neural tube. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Cell development/differentiation

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: axon; cell; cell soma; endoplasmic reticulum; extracellular space

Molecular Function: protein binding

Biological Process: nervous system development; regulation of axon extension
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 Research Articles on OLFM1    1. human chorionic gonadotropin stimulated miR-212, which down-regulated OLFM1 and CTBP1 expression in fallopian and endometrial epithelial cells to favor spheroid attachment
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-OLFM1 antibodyDiseases associated with anti-OLFM1 antibody
 Reference Product  PubMed Publications
 ZEB1 antibody  >2 publications with OLFM1 and ZEB1
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with OLFM1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >2 publications with OLFM1 and Nervous System Diseases
 Necrosis Antibodies  >2 publications with OLFM1 and Necrosis
 Carcinoma Antibodies  >1 publications with OLFM1 and Carcinoma
 Uterine Neoplasms Antibodies  >1 publications with OLFM1 and Uterine Neoplasms
 Learning Disorders Antibodies  >1 publications with OLFM1 and Learning Disorders
 Weight Loss Antibodies  >1 publications with OLFM1 and Weight Loss
Organs/Tissues associated with anti-OLFM1 antibody
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >7 publications with OLFM1 and Eye
 Nerve Antibodies  >5 publications with OLFM1 and Nerve
 Brain Antibodies  >5 publications with OLFM1 and Brain
 Uterus Antibodies  >3 publications with OLFM1 and Uterus
 Embryonic Tissue Antibodies  >3 publications with OLFM1 and Embryonic Tissue
 Ganglia Antibodies  >2 publications with OLFM1 and Ganglia
 Lung Antibodies  >2 publications with OLFM1 and Lung
 Kidney Antibodies  >1 publications with OLFM1 and Kidney
 Pancreas Antibodies  >1 publications with OLFM1 and Pancreas
 Ear Antibodies  >1 publications with OLFM1 and Ear
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