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anti-OXER1 antibody :: Rabbit anti-Human OXER1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS535546 anti-OXER1 antibody
Unit / Price
0.05 mg  /  $625 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

OXER1, Polyclonal Antibody

★Popular Item★
 Also Known As   

OXER1 antibody

 Product Synonym Names    Polyclonal OXER1; Anti-OXER1; 8Z; HM74-like Receptor; OXER 1; tg1019; HEOAD54; OXER -1; 11Z; OXER1; r527; 14Z-Eicosatetraenoic Acid Receptor; 5-oxo-6E
 Product Gene Name   

anti-OXER1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q8TDS5
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    OXER1 antibody was purified by affinity chromatography.
 Form/Format    Immunoaffinity purified liquid in PBS, with <0.15 NaN3.
 Concentration    1.0 mg/ml (lot specific)
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 Biological Significance    Oxoeicosanoid receptor 1 is a protein that in humans is encoded by the OXER1 gene. This protein acts as a receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE). It Seems to be coupled to the Gi/Go, families of heteromeric G proteins. Leukotriene and related receptors act on peroxisome-proliferating receptors (PPARs) as well as the G-protein-coupled leukotriene receptors, and are important in inflammatory signaling pathways.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
 Immunogen    synthetic 18 amino acid peptide from 1st extracellular domain of human OXER1.
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 Preparation and Storage    4 degree C short term, or aliquot and store undiluted at -20 degree C long term.
 Other Notes    Small volumes of anti-OXER1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-OXER1 antibody

   Rabbit polyclonal OXER1 antibody
 Product Categories/Family for anti-OXER1 antibody    Signal Transduction
 Applications Tested/Suitable for anti-OXER1 antibody   

Immunohistochemistry (IHC) Paraffin

 Application Notes for anti-OXER1 antibody    IHC-P: 11 ug/ml
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NCBI/Uniprot data below describe general gene information for OXER1. It may not necessarily be applicable to this product.
 NCBI GI #    22507376
 NCBI GeneID    165140
 NCBI Accession #    NP_683765.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_148962.4 [Other Products]
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 UniProt Primary Accession #    Q8TDS5 [Other Products]
 UniProt Secondary Accession #    Q86WP7; Q8NGW4 [Other Products]
 UniProt Related Accession #    Q8TDS5 [Other Products]
 Molecular Weight    45,811 Da
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 NCBI Official Full Name    oxoeicosanoid receptor 1
 NCBI Official Synonym Full Names    oxoeicosanoid (OXE) receptor 1
 NCBI Official Symbol    OXER1 [Similar Products]
 NCBI Official Synonym Symbols   
GPCR; GPR170; TG1019
[Similar Products]
 NCBI Protein Information    oxoeicosanoid receptor 1
 UniProt Protein Name    Oxoeicosanoid receptor 1
 UniProt Synonym Protein Names   
5-oxo-ETE G-protein coupled receptor; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019
 Protein Family    Oxoeicosanoid receptor
 UniProt Gene Name    OXER1 [Similar Products]
 UniProt Synonym Gene Names    GPR170; TG1019 [Similar Products]
 UniProt Entry Name    OXER1_HUMAN
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 UniProt Comments for OXER1    OXER1: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding

Biological Process: G-protein coupled receptor protein signaling pathway; regulation of cAMP biosynthetic process
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 Research Articles on OXER1    1. Gue1654 as a non-Galphai-biased antagonist of OXE-R that provides a new basis for therapeutic intervention in inflammatory diseases that involve activation of eosinophils, neutrophils, and monocytes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-OXER1 antibodyDiseases associated with anti-OXER1 antibody
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >2 publications with OXER1 and Prostatic Neoplasms
 Immune System Diseases Antibodies  >1 publications with OXER1 and Immune System Diseases
 Respiratory Tract Diseases Antibodies  >1 publications with OXER1 and Respiratory Tract Diseases
Organs/Tissues associated with anti-OXER1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with OXER1 and Blood
 Skin Antibodies  >1 publications with OXER1 and Skin
 Lung Antibodies  >1 publications with OXER1 and Lung
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