AAA65605.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,491 Da
NCBI Official Full Name
octamer binding transcription factor 1
NCBI Official Synonym Full Names
POU class 4 homeobox 1
NCBI Protein Information
POU domain, class 4, transcription factor 1
UniProt Protein Name
POU domain, class 4, transcription factor 1
UniProt Synonym Protein Names
Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1
UniProt Synonym Gene Names
NCBI Summary for 10/1/2017
This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012]
UniProt Comments for 10/1/2017
POU4F1: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily.
Protein type: Cell development/differentiation; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 13q31.1
Cellular Component: nucleoplasm
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; single-stranded DNA binding
Biological Process: axonogenesis; negative regulation of neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; neurite development; neuron fate specification; peripheral nervous system neuron development; positive regulation of transcription from RNA polymerase II promoter; sensory system development; synaptogenesis; trigeminal nerve development
Research Articles on 10/1/2017
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Pathways associated with anti-10/1/2017 antibody
Diseases associated with anti-10/1/2017 antibody
Organs/Tissues associated with anti-10/1/2017 antibody
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