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anti-ODC antibody :: Rabbit anti-Human Ornithine decarboxylase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS715184
Western Blot
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ornithine decarboxylase (ODC), Polyclonal Antibody

 Also Known As   

Rabbit anti-human Ornithine decarboxylase polyclonal Antibody, HRP conjugated

 Product Synonym Names    ODC1
 Product Gene Name   

anti-ODC antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    165640
 3D Structure    ModBase 3D Structure for P11926
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    HRP
 Immunogen    Recombinant human Ornithine decarboxylase protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21515 / sc-34181 / sc-21516 / sc-33539
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ODC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-ODC antibody

   L-ornithine = putrescine + CO2. Inhibited by S-nitrosylation
 Applications Tested/Suitable for anti-ODC antibody   

ELISA (EIA)

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 Western Blot of anti-ODC antibody    anti-ODC antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for ODC. It may not necessarily be applicable to this product.
 NCBI GI #    563580287
 NCBI GeneID    4953
 NCBI Accession #    NP_001274118.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001287189.1 [Other Products]
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 UniProt Primary Accession #    P11926 [Other Products]
 UniProt Secondary Accession #    Q53TU3; Q6LDS9 [Other Products]
 UniProt Related Accession #    P11926 [Other Products]
 Molecular Weight    51,148 Da
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 NCBI Official Full Name    ornithine decarboxylase isoform 1
 NCBI Official Synonym Full Names    ornithine decarboxylase 1
 NCBI Official Symbol    ODC1 [Similar Products]
 NCBI Official Synonym Symbols   
ODC
[Similar Products]
 NCBI Protein Information    ornithine decarboxylase
 UniProt Protein Name    Ornithine decarboxylase
 Protein Family    Ornithine decarboxylase
 UniProt Gene Name    ODC1 [Similar Products]
 UniProt Synonym Gene Names    ODC [Similar Products]
 UniProt Entry Name    DCOR_HUMAN
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 NCBI Summary for ODC    This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]
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 UniProt Comments for ODC    ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - arginine and proline; Cell cycle regulation; Other Amino Acids Metabolism - glutathione; Lyase; EC 4.1.1.17

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: cytoplasm; cytosol; perinuclear region of cytoplasm

Molecular Function: ornithine decarboxylase activity; protein binding; protein homodimerization activity

Biological Process: kidney development; polyamine metabolic process; positive regulation of cell proliferation; putrescine biosynthetic process from ornithine; regulation of amino acid metabolic process; regulation of protein catabolic process; response to virus

Disease: Colorectal Cancer
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 Research Articles on ODC    1. High ODC expression is associated with Medulloblastoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ODC antibodyPathways associated with anti-ODC antibody
 Reference Product  PubMed Publications
 AMD1 antibody  >7 publications with ODC and AMD1
 OAZ2 antibody  >2 publications with ODC and OAZ2
 SRM antibody  >2 publications with ODC and SRM
 AGMAT antibody  >1 publications with ODC and AGMAT
 OAZ1 antibody  >1 publications with ODC and OAZ1
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Polyamines Pathway antibodies  Metabolism Of Polyamines Pathway Diagram
 Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies  Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
 Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies  Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
Diseases associated with anti-ODC antibodyOrgans/Tissues associated with anti-ODC antibody
 Disease Name  Pubmed Publications
 Colorectal Neoplasms Antibodies  >5 publications with ODC and Colorectal Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with ODC and Neoplasms, Experimental
 Colonic Neoplasms Antibodies  >2 publications with ODC and Colonic Neoplasms
 Hypertrophy Antibodies  >1 publications with ODC and Hypertrophy
 Lung Neoplasms Antibodies  >1 publications with ODC and Lung Neoplasms
 Breast Neoplasms Antibodies  >1 publications with ODC and Breast Neoplasms
 Hypertension Antibodies  >1 publications with ODC and Hypertension
 Heart Diseases Antibodies  >1 publications with ODC and Heart Diseases
 Necrosis Antibodies  >1 publications with ODC and Necrosis
 HIV Infections Antibodies  >1 publications with ODC and HIV Infections
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >6 publications with ODC and Muscle
 Prostate Antibodies  >5 publications with ODC and Prostate
 Liver Antibodies  >4 publications with ODC and Liver
 Brain Antibodies  >4 publications with ODC and Brain
 Uterus Antibodies  >3 publications with ODC and Uterus
 Embryonic Tissue Antibodies  >3 publications with ODC and Embryonic Tissue
 Lung Antibodies  >3 publications with ODC and Lung
 Vascular Antibodies  >3 publications with ODC and Vascular
 Ovary Antibodies  >3 publications with ODC and Ovary
 Intestine Antibodies  >2 publications with ODC and Intestine
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