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anti-OGN antibody :: Rabbit anti-Human Osteoinductive Factor, aa187-198 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS621194 anti-OGN antibody
Unit / Price
0.02 mL  /  $440 +1 FREE 8GB USB
0.1 mL  /  $940 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Osteoinductive Factor, aa187-198 (OGN), Polyclonal Antibody

 Also Known As   

Osteoinductive Factor, aa187-198 (OIF, Osteoglycin, OGN, DKFZp586P2421, Mimecan, OG, SLRR3A)

 Product Synonym Names    Anti -Osteoinductive Factor, aa187-198 (OIF, Osteoglycin, OGN, DKFZp586P2421, Mimecan, OG, SLRR3A)
 Product Gene Name   

anti-OGN antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 9; NC_000009.11 (95146249..95166976, complement). Location: 9q22
 OMIM    602383
 3D Structure    ModBase 3D Structure for P20774
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human Osteo-inductive Factor (aa 187-198). There were no cross reactivities obtained with human OIF (aa 108-122), human Osteopontin, and human Bone Sialoprotein
 Purity/Purification    Serum
Serum
 Form/Format    Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute in ddH2O.
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 Immunogen    Synthetic human OIF peptide (aa 187-198) bTG-conjugated (ANAFKKLNNLTE)
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 Preparation and Storage    Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-OGN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-OGN antibody    Antibodies; Abs to Carbohydrates, Glycoproteins
 Applications Tested/Suitable for anti-OGN antibody   

ELISA (EL/EIA)

 Application Notes for anti-OGN antibody    Suitable for use in ELISA.
Dilution: ELISA: 1:1000
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NCBI/Uniprot data below describe general gene information for OGN. It may not necessarily be applicable to this product.
 NCBI GI #    5410302
 NCBI GeneID    4969
 NCBI Accession #    AAD43022.1 [Other Products]
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 UniProt Primary Accession #    P20774 [Other Products]
 UniProt Secondary Accession #    Q6FIB0; Q9UF90; Q9UNK5 [Other Products]
 UniProt Related Accession #    P20774 [Other Products]
 Molecular Weight    33,922 Da [Similar Products]
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 NCBI Official Full Name    osteoinductive factor OIF
 NCBI Official Synonym Full Names    osteoglycin
 NCBI Official Symbol    OGN [Similar Products]
 NCBI Official Synonym Symbols   
OG; OIF; SLRR3A
[Similar Products]
 NCBI Protein Information    mimecan; mimecan proteoglycan; osteoinductive factor; corneal keratan sulfate proteoglycan
 UniProt Protein Name    Mimecan
 UniProt Synonym Protein Names   
Osteoglycin; Osteoinductive factor
 Protein Family    Mimecan
 UniProt Gene Name    OGN [Similar Products]
 UniProt Synonym Gene Names    OIF; SLRR3A; OIF [Similar Products]
 UniProt Entry Name    MIME_HUMAN
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 NCBI Summary for OGN    This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for OGN    OGN: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q22

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; lysosomal lumen; Golgi lumen; extracellular region; vesicle

Molecular Function: protein binding; growth factor activity

Biological Process: keratan sulfate metabolic process; glycosaminoglycan metabolic process; negative regulation of smooth muscle cell proliferation; keratan sulfate biosynthetic process; carbohydrate metabolic process; pathogenesis; keratan sulfate catabolic process
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 Research Articles on OGN    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-OGN antibodyPathways associated with anti-OGN antibody
 Reference Product  PubMed Publications
 KERA antibody  >4 publications with OGN and KERA
 OMD antibody  >4 publications with OGN and OMD
 CHST6 antibody  >1 publications with OGN and CHST6
 LUM antibody  >1 publications with OGN and LUM
 PRELP antibody  >1 publications with OGN and PRELP
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Keratan Sulfate Biosynthesis Pathway antibodies  Keratan Sulfate Biosynthesis Pathway Diagram
 Keratan Sulfate Degradation Pathway antibodies  Keratan Sulfate Degradation Pathway Diagram
 Keratan Sulfate/keratin Metabolism Pathway antibodies  Keratan Sulfate/keratin Metabolism Pathway Diagram
 MPS I - Hurler Syndrome Pathway antibodies  MPS I - Hurler Syndrome Pathway Diagram
 MPS II - Hunter Syndrome Pathway antibodies  MPS II - Hunter Syndrome Pathway Diagram
 MPS IIIA - Sanfilippo Syndrome A Pathway antibodies  MPS IIIA - Sanfilippo Syndrome A Pathway Diagram
 MPS IIIB - Sanfilippo Syndrome B Pathway antibodies  MPS IIIB - Sanfilippo Syndrome B Pathway Diagram
 MPS IIIC - Sanfilippo Syndrome C Pathway antibodies  MPS IIIC - Sanfilippo Syndrome C Pathway Diagram
Diseases associated with anti-OGN antibodyOrgans/Tissues associated with anti-OGN antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >10 publications with OGN and Neoplasms
 Cardiovascular Diseases Antibodies  >6 publications with OGN and Cardiovascular Diseases
 Brain Diseases Antibodies  >5 publications with OGN and Brain Diseases
 Hypertension Antibodies  >4 publications with OGN and Hypertension
 Hypertrophy Antibodies  >3 publications with OGN and Hypertrophy
 Inflammation Antibodies  >2 publications with OGN and Inflammation
 Fibrosis Antibodies  >2 publications with OGN and Fibrosis
 Carcinoma, Hepatocellular Antibodies  >1 publications with OGN and Carcinoma, Hepatocellular
 Cerebral Infarction Antibodies  >1 publications with OGN and Cerebral Infarction
 Breast Neoplasms Antibodies  >1 publications with OGN and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >30 publications with OGN and Bone
 Eye Antibodies  >17 publications with OGN and Eye
 Connective Tissue Antibodies  >14 publications with OGN and Connective Tissue
 Brain Antibodies  >10 publications with OGN and Brain
 Muscle Antibodies  >8 publications with OGN and Muscle
 Pituitary Gland Antibodies  >4 publications with OGN and Pituitary Gland
 Heart Antibodies  >4 publications with OGN and Heart
 Kidney Antibodies  >3 publications with OGN and Kidney
 Embryonic Tissue Antibodies  >3 publications with OGN and Embryonic Tissue
 Nerve Antibodies  >3 publications with OGN and Nerve
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