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anti-P2RY2 antibody :: Rabbit P2RY2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2517953
Western Blot
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

P2RY2, Polyclonal Antibody

★Popular Item★
 Also Known As   

P2RY2 Polyclonal Antibody

 Product Synonym Names    P2U, HP2U, P2U1, P2UR, P2Y2, P2RU1, P2Y2R
 Product Gene Name   

anti-P2RY2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600041
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    2.5mg/mL (lot specific)
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 Immunogen    Synthetic peptide of human P2RY2
 Calculated Molecular Weight: 42kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-P2RY2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-P2RY2 antibody

   The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.
 Applications Tested/Suitable for anti-P2RY2 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-P2RY2 antibody    WB: 1:1000-1:5000
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 Western Blot of anti-P2RY2 antibody    Western blot analysis of HT-29 cell , using P2RY2 Polyclonal Antibody at dilution of 1:1250
anti-P2RY2 antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for P2RY2. It may not necessarily be applicable to this product.
 NCBI GI #    22658489
 NCBI GeneID    5029
 NCBI Accession #    AAN01279.1 [Other Products]
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 UniProt Secondary Accession #    Q96EM8; B2R9W3 [Other Products]
 UniProt Related Accession #    P41231 [Other Products]
 Molecular Weight    42kDa
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 NCBI Official Full Name    purinergic receptor P2RY2
 NCBI Official Synonym Full Names    purinergic receptor P2Y, G-protein coupled, 2
 NCBI Official Symbol    P2RY2 [Similar Products]
 NCBI Official Synonym Symbols   
P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R
[Similar Products]
 NCBI Protein Information    P2Y purinoceptor 2; ATP receptor; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; purinergic receptor P2Y2; purinoceptor P2Y2
 UniProt Protein Name    P2Y purinoceptor 2
 UniProt Synonym Protein Names   
ATP receptor; P2U purinoceptor 1; P2U1; P2U receptor 1; Purinergic receptor
 Protein Family    P2Y purinoceptor
 UniProt Gene Name    P2RY2 [Similar Products]
 UniProt Synonym Gene Names    P2RU1; P2Y2; P2U1 [Similar Products]
 UniProt Entry Name    P2RY2_HUMAN
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 NCBI Summary for P2RY2    The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]
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 UniProt Comments for P2RY2    P2Y2: a G-protein coupled receptor of the rhodopsin family. This family includes hormone, neurotransmitter and light receptors. Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. May participate in control of the cell cycle and proliferation.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 11q13.5-q14.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: purinergic nucleotide receptor activity, G-protein coupled; receptor activity

Biological Process: regulation of vasodilation; cellular ion homeostasis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
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 Research Articles on P2RY2    1. P2Y2 receptor fails to repress IL-6 expression by valve interstitial cells through Akt in calcific aortic valve disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-P2RY2 antibodyPathways associated with anti-P2RY2 antibody
 Reference Product  PubMed Publications
 SRC antibody  >26 publications with P2RY2 and SRC
 ADRBK1 antibody  >5 publications with P2RY2 and ADRBK1
 RGS2 antibody  >2 publications with P2RY2 and RGS2
 CCK antibody  >1 publications with P2RY2 and CCK
 PLCB3 antibody  >1 publications with P2RY2 and PLCB3
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
Diseases associated with anti-P2RY2 antibodyOrgans/Tissues associated with anti-P2RY2 antibody
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >71 publications with P2RY2 and Fibrosis
 Inflammation Antibodies  >64 publications with P2RY2 and Inflammation
 Lung Diseases Antibodies  >33 publications with P2RY2 and Lung Diseases
 Necrosis Antibodies  >26 publications with P2RY2 and Necrosis
 Disease Models, Animal Antibodies  >25 publications with P2RY2 and Disease Models, Animal
 Hypertension Antibodies  >24 publications with P2RY2 and Hypertension
 Kidney Diseases Antibodies  >13 publications with P2RY2 and Kidney Diseases
 Immune System Diseases Antibodies  >13 publications with P2RY2 and Immune System Diseases
 Heart Diseases Antibodies  >10 publications with P2RY2 and Heart Diseases
 Hyperplasia Antibodies  >8 publications with P2RY2 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >125 publications with P2RY2 and Blood
 Muscle Antibodies  >115 publications with P2RY2 and Muscle
 Kidney Antibodies  >91 publications with P2RY2 and Kidney
 Brain Antibodies  >76 publications with P2RY2 and Brain
 Lung Antibodies  >66 publications with P2RY2 and Lung
 Heart Antibodies  >56 publications with P2RY2 and Heart
 Eye Antibodies  >45 publications with P2RY2 and Eye
 Intestine Antibodies  >38 publications with P2RY2 and Intestine
 Ovary Antibodies  >13 publications with P2RY2 and Ovary
 Bone Marrow Antibodies  >10 publications with P2RY2 and Bone Marrow
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