Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow PACSIN2 rightarrow Polyclonal PACSIN2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Leptin receptor (LEPR) Recombinant Protein
 • Latent-transforming growth factor beta-binding protein 2 (LT... ELISA Kit
 • MMP10 Antibody
 • Amanitin ELISA Kit
 • resolvin D1 (RvD1) ELISA Kit
 • Signal Transducer And Activator Of Transcription 3 (STAT3) ELISA Kit
 • 26S proteasome non-ATPase regulatory subunit 11 (PSMD11) Recombinant Protein
 • Haptoglobin (HP) ELISA Kit
 • ARTS Antibody
 • inducible nitric oxide synthase, iNOS ELISA Kit
 • C1 Esterase Inhibitor (SERPING1) Antibody
 • A Disintegrin and Metalloprotease 18 (ADAM18) ELISA Kit
 • Large Multifunctional Peptidase 7 (LMP7) ELISA Kit
 • CNIH2 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PACSIN2 antibody :: Rabbit anti-Human, Mouse PACSIN2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7046486
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PACSIN2, Polyclonal Antibody

★Popular Item★
 Also Known As   

PACSIN2 Antibody

 Product Synonym Names    Protein kinase C and casein kinase substrate in neurons protein 2; Syndapin-2; Syndapin-II; PACSIN2
 Product Gene Name   

anti-PACSIN2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    604960
 3D Structure    ModBase 3D Structure for Q9UNF0
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
Section Bar
 Species    Human
 Immunogen    Recombinant human Protein kinase C and casein kinase substrate in neurons protein 2 protein (240-410AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10417 / sc-10415
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PACSIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-PACSIN2 antibody

   Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
 Applications Tested/Suitable for anti-PACSIN2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Section Bar
 Western Blot (WB) of anti-PACSIN2 antibody    Western blot
All lanes: PACSIN2 antibody at 2.62 ug/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse lung tissue
Lane 3: 3T3 whole cell lysate
Lane 4: Hela whole cell lysate
Lane 5: HL60 whole cell lysate
Lane 6: HepG-2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 56,52 kDa
Observed band size: 56 kDa

anti-PACSIN2 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-PACSIN2 antibody    Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7046486 at dilution 1:100
anti-PACSIN2 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-PACSIN2 antibody    Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7046486 at dilution 1:100
anti-PACSIN2 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PACSIN2. It may not necessarily be applicable to this product.
 NCBI GI #    296841091
 NCBI GeneID    11252
 NCBI Accession #    NP_001171899.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001184970.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9UNF0 [Other Products]
 UniProt Secondary Accession #    O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9Y4V2 [Other Products]
 UniProt Related Accession #    Q9UNF0 [Other Products]
 Molecular Weight    51,353 Da
Table BarTOPTable Bar
 NCBI Official Full Name    protein kinase C and casein kinase substrate in neurons protein 2 isoform A
 NCBI Official Synonym Full Names    protein kinase C and casein kinase substrate in neurons 2
 NCBI Official Symbol    PACSIN2 [Similar Products]
 NCBI Official Synonym Symbols   
SDPII
[Similar Products]
 NCBI Protein Information    protein kinase C and casein kinase substrate in neurons protein 2
 UniProt Protein Name    Protein kinase C and casein kinase substrate in neurons protein 2
 UniProt Synonym Protein Names   
Syndapin-2; Syndapin-II
 Protein Family    Protein kinase C and casein kinase substrate in neurons protein
 UniProt Gene Name    PACSIN2 [Similar Products]
 UniProt Entry Name    PACN2_HUMAN
Section Bar
 NCBI Summary for PACSIN2    This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Section Bar
 UniProt Comments for PACSIN2    PACSIN2: May play a role in vesicle formation and transport. Belongs to the PACSIN family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 22q13.2-q13.33

Cellular Component: caveola; cytoplasm; extrinsic to membrane; focal adhesion; intracellular membrane-bound organelle; nucleoplasm; recycling endosome membrane

Molecular Function: identical protein binding; protein binding; transporter activity

Biological Process: cell projection morphogenesis; regulation of endocytosis
Table BarTOPTable Bar
 Research Articles on PACSIN2    1. PACSIN2 phosphorylation decreases its membrane-binding activity, thereby decreasing its stabilizing effect on caveolae and triggering dynamin-mediated removal of caveolae.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-PACSIN2 antibodyDiseases associated with anti-PACSIN2 antibody
 Reference Product  PubMed Publications
 PACSIN1 antibody  >11 publications with PACSIN2 and PACSIN1
 EHD2 antibody  >8 publications with PACSIN2 and EHD2
 WASL antibody  >5 publications with PACSIN2 and WASL
 EHD3 antibody  >3 publications with PACSIN2 and EHD3
 FASLG antibody  >1 publications with PACSIN2 and FASLG
 DNM2 antibody  >1 publications with PACSIN2 and DNM2
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1 publications with PACSIN2 and Cardiovascular Diseases
Organs/Tissues associated with anti-PACSIN2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with PACSIN2 and Brain
 Nerve Antibodies  >6 publications with PACSIN2 and Nerve
 Blood Antibodies  >4 publications with PACSIN2 and Blood
 Vascular Antibodies  >3 publications with PACSIN2 and Vascular
 Thyroid Antibodies  >2 publications with PACSIN2 and Thyroid
 Muscle Antibodies  >2 publications with PACSIN2 and Muscle
 Heart Antibodies  >2 publications with PACSIN2 and Heart
 Kidney Antibodies  >2 publications with PACSIN2 and Kidney
 Lung Antibodies  >2 publications with PACSIN2 and Lung
 Pancreas Antibodies  >1 publications with PACSIN2 and Pancreas
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions