NP_001035224.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,157 Da
NCBI Official Full Name
paralemmin-1 isoform 2
NCBI Official Synonym Full Names
paralemmin
NCBI Protein Information
paralemmin-1
UniProt Protein Name
Paralemmin-1
UniProt Synonym Protein Names
Paralemmin
UniProt Synonym Gene Names
NCBI Summary for PALM
This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for PALM
paralemmin: Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. Belongs to the paralemmin family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cytoplasmic vesicle; filopodium membrane; integral to plasma membrane; intracellular membrane-bound organelle; nucleoplasm; nucleus; plasma membrane
Molecular Function: protein binding
Biological Process: cell motility; negative regulation of adenylate cyclase activity; negative regulation of dopamine receptor signaling pathway; positive regulation of filopodium formation
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Diseases associated with anti-PALM antibody
Organs/Tissues associated with anti-PALM antibody
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