NP_006371.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
amyloid protein-binding protein 2 isoform 1
NCBI Official Synonym Full Names
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
NCBI Protein Information
amyloid protein-binding protein 2
UniProt Protein Name
Amyloid protein-binding protein 2
UniProt Synonym Protein Names
Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1
UniProt Synonym Gene Names
UniProt Entry Name
APBP2_HUMAN
NCBI Summary for APPBP2
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Comments for APPBP2
APPBP2: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
Protein type: Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 17q23.2
Cellular Component: microtubule; microtubule associated complex; cytoplasmic vesicle membrane; cytoplasm; nucleus
Molecular Function: protein binding; microtubule motor activity
Biological Process: intracellular protein transport; intracellular transport; metabolic process
Product References and Citations for anti-APPBP2 antibody
Zheng,P., Proc. Natl. Acad. Sci. U.S.A. 95 (25), 14745-14750 (1998)
Research Articles on APPBP2
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Products associated with anti-APPBP2 antibody
Diseases associated with anti-APPBP2 antibody
Organs/Tissues associated with anti-APPBP2 antibody
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