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anti-PDXK antibody :: Rabbit anti-Human, Mouse PDXK Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7043630
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PDXK, Polyclonal Antibody

★Popular Item★
 Also Known As   

PDXK Antibody

 Product Synonym Names    Pyridoxal kinase; Pyridoxine kinase; PDXK; C21orf124; C21orf97; PKH; PNK; PRED79
 Product Gene Name   

anti-PDXK antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    179020
 3D Structure    ModBase 3D Structure for O00764
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Pyridoxal kinase protein (1-312AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-50961 / sc-67361
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PDXK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PDXK antibody

   Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
 Applications Tested/Suitable for anti-PDXK antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-PDXK antibody    Western blot
All lanes: PDXK antibody at 5.63ug/ml
Lane 1:mouse liver tissue
Lane 2:Hela whole cell lysate
Lane 3:mouse kidney tissue
Lane 4:HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 36,32,27 kDa
Observed band size: 35 kDa

anti-PDXK antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-PDXK antibody    Immunohistochemistry of paraffin-embedded human breast cancer using MBS7043630 at dilution 1:100
anti-PDXK antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-PDXK antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7043630 at dilution 1:100
anti-PDXK antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for PDXK. It may not necessarily be applicable to this product.
 NCBI GI #    4505701
 NCBI GeneID    8566
 NCBI Accession #    NP_003672.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003681.4 [Other Products]
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 UniProt Primary Accession #    O00764 [Other Products]
 UniProt Secondary Accession #    Q7Z2Y0; Q9BS02 [Other Products]
 UniProt Related Accession #    O00764 [Other Products]
 Molecular Weight    26,827 Da
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 NCBI Official Full Name    pyridoxal kinase
 NCBI Official Synonym Full Names    pyridoxal (pyridoxine, vitamin B6) kinase
 NCBI Official Symbol    PDXK [Similar Products]
 NCBI Official Synonym Symbols   
PKH; PNK; PRED79; C21orf97; HEL-S-1a; C21orf124
[Similar Products]
 NCBI Protein Information    pyridoxal kinase
 UniProt Protein Name    Pyridoxal kinase
 UniProt Synonym Protein Names   
Pyridoxine kinase
 Protein Family    Pyridoxine kinase
 UniProt Gene Name    PDXK [Similar Products]
 UniProt Synonym Gene Names    C21orf124; C21orf97; PKH; PNK [Similar Products]
 UniProt Entry Name    PDXK_HUMAN
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 NCBI Summary for PDXK    The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PDXK    PDXK: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Belongs to the pyridoxine kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - vitamin B6; Kinase, other; EC 2.7.1.35

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: ATP binding; lithium ion binding; magnesium ion binding; potassium ion binding; protein homodimerization activity; pyridoxal kinase activity; pyridoxal phosphate binding; sodium ion binding; zinc ion binding

Biological Process: cell proliferation; pyridoxal 5'-phosphate salvage; pyridoxal phosphate biosynthetic process; vitamin B6 metabolic process
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 Research Articles on PDXK    1. The affected pyridoxine metabolism is discussed as an inborn genetic trait in epilepsy in general, rather than a specific sign of pyridoxine-dependent epilepsy solely.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-PDXK antibodyDiseases associated with anti-PDXK antibody
 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 Vitamin B6 Metabolism Pathway antibodies  Vitamin B6 Metabolism Pathway Diagram
 Vitamin B6 Metabolism Pathway antibodies  Vitamin B6 Metabolism Pathway Diagram
 Vitamins B6 Activation To Pyridoxal Phosphate Pathway antibodies  Vitamins B6 Activation To Pyridoxal Phosphate Pathway Diagram
 Pyridoxal 5'-phosphate Salvage Pathway antibodies  Pyridoxal 5'-phosphate Salvage Pathway Diagram
 Pyridoxal 5'-phosphate Salvage I Pathway antibodies  Pyridoxal 5'-phosphate Salvage I Pathway Diagram
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >1 publications with PDXK and Heart Diseases
 Heart Defects, Congenital Antibodies  >1 publications with PDXK and Heart Defects, Congenital
 Poisoning Antibodies  >1 publications with PDXK and Poisoning
 Disease Models, Animal Antibodies  >1 publications with PDXK and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >1 publications with PDXK and Neoplasms, Experimental
 Weight Loss Antibodies  >1 publications with PDXK and Weight Loss
 Atrophy Antibodies  >1 publications with PDXK and Atrophy
 Inflammation Antibodies  >1 publications with PDXK and Inflammation
 Hyperplasia Antibodies  >1 publications with PDXK and Hyperplasia
 Seizures Antibodies  >1 publications with PDXK and Seizures
Organs/Tissues associated with anti-PDXK antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >6 publications with PDXK and Lung
 Brain Antibodies  >3 publications with PDXK and Brain
 Liver Antibodies  >2 publications with PDXK and Liver
 Muscle Antibodies  >1 publications with PDXK and Muscle
 Blood Antibodies  >1 publications with PDXK and Blood
 Heart Antibodies  >1 publications with PDXK and Heart
 Embryonic Tissue Antibodies  >1 publications with PDXK and Embryonic Tissue
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