Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow PDXP rightarrow Polyclonal PDXP  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • Anti-Smooth Muscle Antibody (ASMA) ELISA Kit
 • Chloride Channel Protein 1 (CLC1) ELISA Kit
 • Cathelicidin Antimicrobial (CAMP) Recombinant Protein
 • Luteinizing Hormone (LH) ELISA Kit
 • PLCG2 Antibody
 • Interleukin 10 (IL10) Recombinant Protein
 • RPS14 Antibody
 • Nuclear pore membrane glycoprotein 210, NUP210 ELISA Kit
 • ADAMTS4 Antibody
 • Beta-defensin 4 (Defb4) ELISA Kit
 • Fibroblast Growth Factor-basic (mFGF 2) Recombinant Protein
 • c-Jun Antibody
 • Tenascin C (TNC) Antibody
 • GUCY2D Recombinant Protein
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PDXP antibody :: Goat PDXP Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422888
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PDXP, Polyclonal Antibody

 Also Known As   

Goat anti-PDXP Antibody

 Product Synonym Names    PDXP; pyridoxal (pyridoxine, vitamin B6) phosphatase; CIN; FLJ32703; PLP; dJ37E16.5; chronophin; pyridoxal phosphatase; pyridoxal phosphate phosphatase; chronophin antibody; CIN antibody; dJ37E16.5 antibody; FLJ32703 antibody; PLP antibody; pyridoxal (pyridoxine; vitamin B6) phosphatase antibody; pyridoxal phosphatase antibody; pyridoxal phosphate phosphatase antibody; PDXP antibody
 Product Gene Name   

anti-PDXP antibody

[Similar Products]
 Antibody/Peptide Pairs    PDXP peptide (MBS427672) is used for blocking the activity of PDXP antibody (MBS422888)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Immunogen Sequence    QHDLVPHYYV ES
 OMIM    609246
Section Bar
 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human, Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat, Cow
Section Bar
 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
Section Bar
 Immunogen    Peptide with sequence C-QHDLVPHYYVES, from the C Terminus of the protein sequence according to NP_064711.1.
 Epitope    C Terminus
Section Bar
 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-PDXP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-PDXP antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-PDXP antibody    Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 32kDa band observed in Human and Rat Heart lysates and in Mouse and Rat Brain lysates (calculated MW of 31.7kDa according to NP_064711.1). Recommended concentration: 0.1-0.3ug/ml.
Section Bar
 Western Blot (WB) of anti-PDXP antibody    (0.1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-PDXP antibody Western Blot (WB) (WB) image
Section Bar
 Western Blot (WB) of anti-PDXP antibody    (0.1ug/ml) staining of Mouse (A) and Rat (B) Brain lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-PDXP antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PDXP. It may not necessarily be applicable to this product.
 NCBI GI #    10092677
 NCBI GeneID    57026
 NCBI Accession #    NP_064711.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020315.4 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q9UGY2 [Other Products]
 UniProt Related Accession #    Q96GD0 [Other Products]
 Molecular Weight    31,698 Da
Table BarTOPTable Bar
 NCBI Official Full Name    pyridoxal phosphate phosphatase
 NCBI Official Synonym Full Names    pyridoxal phosphatase
 NCBI Official Symbol    PDXP [Similar Products]
 NCBI Official Synonym Symbols   
CIN; PLP; dJ37E16.5
[Similar Products]
 NCBI Protein Information    pyridoxal phosphate phosphatase
 UniProt Protein Name    Pyridoxal phosphate phosphatase
 UniProt Synonym Protein Names   
 Protein Family    Pyridoxal phosphate phosphatase
 UniProt Gene Name    PDXP [Similar Products]
 UniProt Synonym Gene Names    CIN; PLP; PLPP; PLP phosphatase [Similar Products]
 UniProt Entry Name    PLPP_HUMAN
Section Bar
 NCBI Summary for PDXP    Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).[supplied by OMIM, Mar 2008]
Section Bar
 UniProt Comments for PDXP    PDXP: Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho- tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PMP) and pyridoxine 5'-phosphate (PNP), with a highest activity with PLP followed by PNP. Homodimer. Ubiquitous. Highly expressed in all the regions of central nerve system except the spinal cord. Also expressed at high level in liver and testis. In fetus, it is weakly expressed in all organs except brain. Inhibited by NaF, Zn(2+), Ca(2+), Mn(2+) and EDTA. Belongs to the HAD-like hydrolase superfamily.

Protein type: Cofactor and Vitamin Metabolism - vitamin B6; Protein phosphatase, Ser/Thr (non-receptor); EC; EC; Cell cycle regulation

Chromosomal Location of Human Ortholog: 22q12.3

Cellular Component: actin cytoskeleton; cleavage furrow; cytosol; lamellipodium; midbody; plasma membrane

Molecular Function: heat shock protein binding; magnesium ion binding; phosphoprotein phosphatase activity; phosphoserine phosphatase activity; protein binding; pyridoxal phosphatase activity

Biological Process: actin rod formation; positive regulation of actin filament depolymerization; protein amino acid dephosphorylation; pyridoxal phosphate catabolic process; regulation of cytokinesis; regulation of mitosis
Table BarTOPTable Bar
 Research Articles on PDXP    1. Chronophin has a role in coordinating cell leading edge dynamics by controlling active cofilin levels
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-PDXP antibodyDiseases associated with anti-PDXP antibody
 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Vitamin B6 Metabolism Pathway antibodies  Vitamin B6 Metabolism Pathway Diagram
 Vitamin B6 Metabolism Pathway antibodies  Vitamin B6 Metabolism Pathway Diagram
 Pyridoxal 5'-phosphate Salvage Pathway antibodies  Pyridoxal 5'-phosphate Salvage Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >1 publications with PDXP and Neoplasm Metastasis
 Inflammation Antibodies  >1 publications with PDXP and Inflammation
Organs/Tissues associated with anti-PDXP antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with PDXP and Lung
 Brain Antibodies  >2 publications with PDXP and Brain
 Liver Antibodies  >1 publications with PDXP and Liver
 Muscle Antibodies  >1 publications with PDXP and Muscle
 Blood Antibodies  >1 publications with PDXP and Blood
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions