NP_071404.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,386 Da
NCBI Official Full Name
p53 apoptosis effector related to PMP-22
NCBI Official Synonym Full Names
PERP, TP53 apoptosis effector
NCBI Official Synonym Symbols
THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1 [Similar Products]
NCBI Protein Information
p53 apoptosis effector related to PMP-22
UniProt Protein Name
p53 apoptosis effector related to PMP-22
UniProt Synonym Protein Names
Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THW
UniProt Synonym Gene Names
UniProt Entry Name
PERP_HUMAN
UniProt Comments for PERP
PERP: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Belongs to the TMEM47 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion; Mitochondrial
Chromosomal Location of Human Ortholog: 6q24
Cellular Component: cell junction; desmosome; Golgi apparatus; integral to plasma membrane; mitochondrion; plasma membrane
Biological Process: heterotypic cell-cell adhesion; Notch signaling pathway; positive regulation of proteolysis; regulation of apoptosis
Research Articles on PERP
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Products associated with anti-PERP antibody
Pathways associated with anti-PERP antibody
Diseases associated with anti-PERP antibody
Organs/Tissues associated with anti-PERP antibody
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