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anti-PGE2 antibody :: Rabbit PGE2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS480053
Specificity Notes
Unit / Price
1 mL  /  $170 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PGE2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-PGE2, Rabbit Polyclonal

 Product Synonym Names    Anti-Prostaglandin E2
 Product Gene Name   

anti-PGE2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608152
 3D Structure    ModBase 3D Structure for Q9H7Z7
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 Clonality    Polyclonal
 Host    Rabbit
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 Specificity    Not species specific. May not exhibit utility when using in a rabbit experimental model.
 Purity/Purification    Not purified
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 Storage Buffer    PBS; 0.1% Sodium Azide
 Sensitivity    130 pg/assay (IC50)
 Immunogen    Prostaglandin E2
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 Preparation and Storage    At -80 degree C. AVOID REPEATED FREEZE THAWS.
 Other Notes    Small volumes of anti-PGE2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PGE2 antibody

   Description: This rabbit polyclonal antibody is specific to Prostaglandin E2 and other associated pathway specific arachidonate derived molecules. This antibody is presented as antiserum.
 Applications Tested/Suitable for anti-PGE2 antibody   

Radioimmunoassay (RIA), ELISA (EIA)

 Application Notes for anti-PGE2 antibody    RIA: 1:25 dilution
May also have utility in ELISA.
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 Specificity Notes of anti-PGE2 antibody    anti-PGE2 antibody Specificity Notes image
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NCBI/Uniprot data below describe general gene information for PGE2. It may not necessarily be applicable to this product.
 NCBI GI #    73921741
 NCBI GeneID    80142
 NCBI Accession #    Q9H7Z7.1 [Other Products]
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 UniProt Primary Accession #    Q9H7Z7 [Other Products]
 UniProt Secondary Accession #    Q53EW9; Q5SYV6; Q96GI0; Q96GL2 [Other Products]
 UniProt Related Accession #    Q9H7Z7 [Other Products]
 Molecular Weight    41,943 Da
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 NCBI Official Full Name    Prostaglandin E synthase 2
 NCBI Official Synonym Full Names    prostaglandin E synthase 2
 NCBI Official Symbol    PTGES2 [Similar Products]
 NCBI Official Synonym Symbols   
GBF1; GBF-1; PGES2; C9orf15; mPGES-2
[Similar Products]
 NCBI Protein Information    prostaglandin E synthase 2; GATE-binding factor 1; gamma-interferon-activated transcriptional element-binding factor 1; mPGE synthase-2; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; microsomal prostaglandin E synthase-2; prostaglandin-H(2) E-isomerase
 UniProt Protein Name    Prostaglandin E synthase 2
 UniProt Synonym Protein Names   
Membrane-associated prostaglandin E synthase-2
 UniProt Gene Name    PTGES2 [Similar Products]
 UniProt Synonym Gene Names    C9orf15; PGES2; mPGES-2 [Similar Products]
 UniProt Entry Name    PGES2_HUMAN
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 NCBI Summary for PGE2    The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
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 UniProt Comments for PGE2    PTGES2: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Belongs to the GST superfamily.

Protein type: Isomerase; EC 5.3.99.3; Lipid Metabolism - arachidonic acid; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: Golgi membrane; mitochondrion; perinuclear region of cytoplasm; integral to membrane; cytosol; nucleus

Molecular Function: DNA binding; glutathione binding; electron carrier activity; lyase activity; heme binding; protein disulfide oxidoreductase activity; prostaglandin-E synthase activity

Biological Process: secretion; cell redox homeostasis; positive regulation of transcription, DNA-dependent; prostaglandin biosynthetic process
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Product References and Citations for anti-PGE2 antibody

   Levine, L., Measurement of Arachidonic Acid Metabolites by
Radioimmunoassay. In: Manual of Clinical Laboratory
Immunology (3rd Edition). J.L. Fahey, H. Friedman and N.L. Rose
(eds.). Amer. Soc. Microbiol. pp. 685-691 (1986).
Granstrom, E. and Lindgren, J.A., Radioimmunoassay of
Prostaglandins and Related Compounds. In: Prostaglandins:
Biology and Chemistry of Prostaglandins and Related
Eicosanoids, P.B. Curtis-Prior, (Ed.) Churchill Livingstone, New
York, pp. 115-12
6.
Powell, W.S., Rapid Extraction of Arachidonic Acid Metabolites From
Biological Samples Using Octadecylsilyl Silica. Meth. Enzymol.
86: 467-476 (1982).
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 Research Articles on PGE2    1. Four single nucleotide polymorphisms in two genes in the PGE2 family, PTGES2 and PTGER4, were significantly associated with primary graft dysfunction after lung transplantation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PGE2 antibodyPathways associated with anti-PGE2 antibody
 Reference Product  PubMed Publications
 PTGS2 antibody  >10 publications with PGE2 and PTGS2
 PTGES3 antibody  >8 publications with PGE2 and PTGES3
 PTGS1 antibody  >5 publications with PGE2 and PTGS1
 PTGIS antibody  >2 publications with PGE2 and PTGIS
 HPGDS antibody  >1 publications with PGE2 and HPGDS
 PTGDS antibody  >1 publications with PGE2 and PTGDS
 TBXAS1 antibody  >1 publications with PGE2 and TBXAS1
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 IFN-gamma Pathway antibodies  IFN-gamma Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
Diseases associated with anti-PGE2 antibodyOrgans/Tissues associated with anti-PGE2 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with PGE2 and Carcinoma
 Obesity Antibodies  >2 publications with PGE2 and Obesity
 Reperfusion Injury Antibodies  >1 publications with PGE2 and Reperfusion Injury
 Anoxia Antibodies  >1 publications with PGE2 and Anoxia
 Neoplasms, Experimental Antibodies  >1 publications with PGE2 and Neoplasms, Experimental
 Insulin Resistance Antibodies  >1 publications with PGE2 and Insulin Resistance
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with PGE2 and Prenatal Exposure Delayed Effects
 Inflammation Antibodies  >1 publications with PGE2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >4 publications with PGE2 and Uterus
 Blood Antibodies  >3 publications with PGE2 and Blood
 Embryonic Tissue Antibodies  >2 publications with PGE2 and Embryonic Tissue
 Vascular Antibodies  >1 publications with PGE2 and Vascular
 Ovary Antibodies  >1 publications with PGE2 and Ovary
 Mammary Gland Antibodies  >1 publications with PGE2 and Mammary Gland
 Prostate Antibodies  >1 publications with PGE2 and Prostate
 Lung Antibodies  >1 publications with PGE2 and Lung
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