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anti-PGLYRP3 antibody :: Rabbit anti-Human PGLYRP3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS852923
Testing Data
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PGLYRP3, Polyclonal Antibody

 Also Known As   

PGLYRP3 Antibody

 Product Gene Name   

anti-PGLYRP3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608197
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Lyophilized PGLYRP3 antibody purified by protein affinity column containing 1% BSA and 0.02% NaN3
 Concentration    100ug/200ul (lot specific)
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 Source Note    Rabbit polyclonal PGLYRP3(1) antibody was raised against a recombinate human PGLYRP3 protein 45-288aa (BC069741).
 Reactivity Note    Predicted: Mouse, Rat; Not yet tested in other species.
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 Other Notes    Small volumes of anti-PGLYRP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-PGLYRP3 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-PGLYRP3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-PGLYRP3 antibody    ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Optimal dilutions/concentrations should
be determined by the end user.
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 Testing Data of anti-PGLYRP3 antibody    anti-PGLYRP3 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for PGLYRP3. It may not necessarily be applicable to this product.
 NCBI GI #    16418405
 NCBI GeneID    114771
 NCBI Accession #    BC069741 [Other Products]
 NCBI GenBank Nucleotide #    NM_052891.1 [Other Products]
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 UniProt Secondary Accession #    Q5SY65; A1A4U8 [Other Products]
 UniProt Related Accession #    Q96LB9 [Other Products]
 Molecular Weight    37,611 Da
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 NCBI Official Full Name    peptidoglycan recognition protein 3
 NCBI Official Synonym Full Names    peptidoglycan recognition protein 3
 NCBI Official Symbol    PGLYRP3 [Similar Products]
 NCBI Official Synonym Symbols   
PGRPIA; PGRP-Ialpha
[Similar Products]
 NCBI Protein Information    peptidoglycan recognition protein 3; PGLYRPIalpha; PGRP-I-alpha; peptidoglycan recognition protein I alpha; peptidoglycan recognition protein I-alpha; peptidoglycan recognition protein-I-alpha; peptidoglycan recognition protein intermediate alpha
 UniProt Protein Name    Peptidoglycan recognition protein 3
 UniProt Synonym Protein Names   
Peptidoglycan recognition protein I-alpha; PGLYRPIalpha; PGRP-I-alpha; Peptidoglycan recognition protein intermediate alpha
 Protein Family    Peptidoglycan recognition protein
 UniProt Gene Name    PGLYRP3 [Similar Products]
 UniProt Synonym Gene Names    PGRPIA; PGLYRPIalpha; PGRP-I-alpha [Similar Products]
 UniProt Entry Name    PGRP3_HUMAN
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 NCBI Summary for PGLYRP3    This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
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 UniProt Comments for PGLYRP3    PGLYRP3: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: membrane; extracellular region; intracellular

Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity

Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; innate immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process
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Product References and Citations for anti-PGLYRP3 antibody

   (1) Davila,S., Froeling,F.E., Tan,A., et al. New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. 11 (3), 232-238 (2010)
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 Research Articles on PGLYRP3    1. Results describe the function of mammalian antimicrobial peptidoglycan recognition proteins 3 and 4, and show that they are a new class of bactericidal and bacteriostatic proteins.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-PGLYRP3 antibodyOrgans/Tissues associated with anti-PGLYRP3 antibody
 Disease Name  Pubmed Publications
 Colitis Antibodies  >4 publications with PGLYRP3 and Colitis
 Weight Loss Antibodies  >1 publications with PGLYRP3 and Weight Loss
 Hyperplasia Antibodies  >1 publications with PGLYRP3 and Hyperplasia
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies  >1 publications with PGLYRP3 and Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >4 publications with PGLYRP3 and Skin
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