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anti-PIGF antibody :: Rabbit anti-Human PIGF PIGF Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS535816 anti-PIGF antibody
Unit / Price
0.05 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PIGF, Polyclonal Antibody

 Also Known As   

PIGF antibody

 Product Synonym Names    Polyclonal PIGF; Anti-PIGF; Placenta Growth Factor-1; PIGF-1; PIGF; PGF
 Product Gene Name   

anti-PIGF antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600153
 3D Structure    ModBase 3D Structure for Q07326
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human PIGF
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 Form/Format    Lyophilized from PBS, pH 7.2.
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 Biological Significance    PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration.
 Immunogen    PIGF antibody was raised in rabbit using highly pure recombinant human PlGF as the immunogen.
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 Preparation and Storage    Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-PIGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PIGF antibody

   Affinity purified Rabbit polyclonal PIGF antibody
 Product Categories/Family for anti-PIGF antibody    Cytokines & Growth Factors; Purified Polyclonal Antibodies
 Applications Tested/Suitable for anti-PIGF antibody   

ELISA (EIA), Inhibition, Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for PIGF. It may not necessarily be applicable to this product.
 NCBI GI #    4505797
 NCBI GeneID    5281
 NCBI Accession #    NP_002634 [Other Products]
 NCBI GenBank Nucleotide #    NM_002643.3 [Other Products]
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 UniProt Primary Accession #    Q07326 [Other Products]
 UniProt Secondary Accession #    Q8WW20 [Other Products]
 UniProt Related Accession #    Q07326 [Other Products]
 Molecular Weight    29.7 kDa (predicted detection band MW)
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 NCBI Official Full Name    phosphatidylinositol-glycan biosynthesis class F protein isoform 1
 NCBI Official Synonym Full Names    phosphatidylinositol glycan anchor biosynthesis, class F
 NCBI Official Symbol    PIGF [Similar Products]
 NCBI Protein Information    phosphatidylinositol-glycan biosynthesis class F protein
 UniProt Protein Name    Phosphatidylinositol-glycan biosynthesis class F protein
 UniProt Synonym Protein Names   
GPI11 homolog
 Protein Family    Phosphatidylinositol-glycan biosynthesis class F protein
 UniProt Gene Name    PIGF [Similar Products]
 UniProt Synonym Gene Names    PIG-F [Similar Products]
 UniProt Entry Name    PIGF_HUMAN
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 NCBI Summary for PIGF    This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PIGF    PIGF: Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. Belongs to the PIGF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p21-p16

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: ethanolaminephosphotransferase activity

Biological Process: cellular protein metabolic process; preassembly of GPI anchor in ER membrane; GPI anchor biosynthetic process; C-terminal protein lipidation; post-translational protein modification
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 Research Articles on PIGF    1. In chronic kidney patients not yet on dialysis, higher serum level of PIGF are associated with increased mortality, but not cardiovascular events.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PIGF antibodyPathways associated with anti-PIGF antibody
 Reference Product  PubMed Publications
 PIGS antibody  >6 publications with PIGF and PIGS
 PIGA antibody  >4 publications with PIGF and PIGA
 PIGB antibody  >3 publications with PIGF and PIGB
 PIGC antibody  >2 publications with PIGF and PIGC
 PIGO antibody  >2 publications with PIGF and PIGO
 PIGG antibody  >2 publications with PIGF and PIGG
 PGF antibody  >1 publications with PIGF and PGF
 PIGK antibody  >1 publications with PIGF and PIGK
 Products by Pathway  Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 GPI-anchor Biosynthesis, Core Oligosaccharide Pathway antibodies  GPI-anchor Biosynthesis, Core Oligosaccharide Pathway Diagram
 GPI-anchor Biosynthesis, Core Oligosaccharide Pathway antibodies  GPI-anchor Biosynthesis, Core Oligosaccharide Pathway Diagram
 Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies  Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
 Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies  Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies  Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway antibodies  Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway Diagram
Diseases associated with anti-PIGF antibodyOrgans/Tissues associated with anti-PIGF antibody
 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >42 publications with PIGF and Vascular Diseases
 Hypertension Antibodies  >34 publications with PIGF and Hypertension
 Cardiovascular Diseases Antibodies  >27 publications with PIGF and Cardiovascular Diseases
 Proteinuria Antibodies  >15 publications with PIGF and Proteinuria
 Inflammation Antibodies  >12 publications with PIGF and Inflammation
 Edema Antibodies  >11 publications with PIGF and Edema
 Lung Neoplasms Antibodies  >10 publications with PIGF and Lung Neoplasms
 Heart Diseases Antibodies  >9 publications with PIGF and Heart Diseases
 Kidney Diseases Antibodies  >8 publications with PIGF and Kidney Diseases
 Lung Diseases Antibodies  >8 publications with PIGF and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >146 publications with PIGF and Blood
 Placenta Antibodies  >123 publications with PIGF and Placenta
 Embryonic Tissue Antibodies  >29 publications with PIGF and Embryonic Tissue
 Liver Antibodies  >21 publications with PIGF and Liver
 Eye Antibodies  >17 publications with PIGF and Eye
 Muscle Antibodies  >17 publications with PIGF and Muscle
 Brain Antibodies  >16 publications with PIGF and Brain
 Lung Antibodies  >16 publications with PIGF and Lung
 Heart Antibodies  >14 publications with PIGF and Heart
 Kidney Antibodies  >12 publications with PIGF and Kidney
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