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anti-PIH1D1 antibody :: Rabbit anti-Human PIH1D1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7000171
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PIH1D1, Polyclonal Antibody

★Popular Item★
 Also Known As   

PIH1D1 Antibody

 Product Synonym Names    PIH1 domain-containing protein 1; PIH1D1; NOP17; Nucleolar protein 17 homolog
 Product Gene Name   

anti-PIH1D1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611480
 3D Structure    ModBase 3D Structure for Q9NWS0
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Affinity Purified
 Form/Format    Liquid
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 Immunogen    Recombinant human PIH1 domain-containing protein 1 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168777 / sc-168778
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PIH1D1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PIH1D1 antibody

   Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
 Applications Tested/Suitable for anti-PIH1D1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-PIH1D1 antibody    Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
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 Immunohistochemistry (IHC) of anti-PIH1D1 antibody    Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7000171 at dilution of 1:100
anti-PIH1D1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-PIH1D1 antibody    Immunofluorescence staining of Hela cells cells with MBS7000171 at 1:200,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 degree C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
anti-PIH1D1 antibody Immunofluorescence (IF) image
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 Immunoprecipitation (IP) of anti-PIH1D1 antibody    Immunoprecipitating PIH1D1 in Hela whole cell lysate
Lane 1: Rabbit control IgG (1ug)instead of MBS7000171 in Hela whole cell lysate. For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: MBS7000171 (6ug)+ Hela whole cell lysate (500ug)
Lane 3: Hela whole cell lysate (10ug)

anti-PIH1D1 antibody Immunoprecipitation (IP) (IP) image
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NCBI/Uniprot data below describe general gene information for PIH1D1. It may not necessarily be applicable to this product.
 NCBI GI #    8923598
 NCBI GeneID    55011
 NCBI Accession #    NP_060386.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_017916.2 [Other Products]
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 UniProt Primary Accession #    Q9NWS0 [Other Products]
 UniProt Secondary Accession #    Q9BVL0; B4DGN7; B4E2X7 [Other Products]
 UniProt Related Accession #    Q9NWS0 [Other Products]
 Molecular Weight    21,376 Da
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 NCBI Official Full Name    PIH1 domain-containing protein 1
 NCBI Official Synonym Full Names    PIH1 domain containing 1
 NCBI Official Symbol    PIH1D1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    PIH1 domain-containing protein 1
 UniProt Protein Name    PIH1 domain-containing protein 1
 UniProt Synonym Protein Names   
Nucleolar protein 17 homolog
 Protein Family    PIH1 domain-containing protein
 UniProt Gene Name    PIH1D1 [Similar Products]
 UniProt Synonym Gene Names    NOP17 [Similar Products]
 UniProt Entry Name    PIHD1_HUMAN
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 UniProt Comments for PIH1D1    PIH1D1: a protein of unknown function.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: ATPase binding; histone binding; phosphoprotein binding; protein binding; protein kinase binding

Biological Process: box C/D snoRNP assembly; chromatin remodeling; epithelial cell differentiation; positive regulation of protein complex assembly; regulation of histone H3-K4 methylation; snoRNA localization; transcription, DNA-dependent
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 Research Articles on PIH1D1    1. We propose that protein complexes assembled by the R2TP complex are defined by phosphorylation of a specific motif and recognition by the PIH1D1 subunit
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PIH1D1 antibodyDiseases associated with anti-PIH1D1 antibody
 Reference Product  PubMed Publications
 RPAP3 antibody  >8 publications with PIH1D1 and RPAP3
 PIH1 antibody  >6 publications with PIH1D1 and PIH1
 RUVBL2 antibody  >5 publications with PIH1D1 and RUVBL2
 RUVBL1 antibody  >5 publications with PIH1D1 and RUVBL1
 MTOR antibody  >2 publications with PIH1D1 and MTOR
 TTI1 antibody  >1 publications with PIH1D1 and TTI1
 NOP58 antibody  >1 publications with PIH1D1 and NOP58
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with PIH1D1 and Breast Neoplasms
Organs/Tissues associated with anti-PIH1D1 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with PIH1D1 and Muscle
 Placenta Antibodies  >1 publications with PIH1D1 and Placenta
 Heart Antibodies  >1 publications with PIH1D1 and Heart
 Lung Antibodies  >1 publications with PIH1D1 and Lung
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