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anti-PLEKHG3 antibody :: Rabbit anti-Human PLEKHG3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9203431
Unit / Price
0.08 mL  /  $150 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PLEKHG3, Polyclonal Antibody

★Popular Item★
 Also Known As   

PLEKHG3 Antibody (C-term)

 Product Synonym Names    Pleckstrin homology domain-containing family G member 3; PH domain-containing family G member 3; PLEKHG3; KIAA0599
 Product Gene Name   

anti-PLEKHG3 antibody

[Similar Products]
 Antibody/Peptide Pairs    PLEKHG3 peptide (MBS9218198) is used for blocking the activity of PLEKHG3 antibody (MBS9203431)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    1178-1207
 3D Structure    ModBase 3D Structure for A1L390
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 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    This PLEKHG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1178-1207 amino acids from the C-terminal region of human PLEKHG3.
 Purity/Purification    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
 Concentration    Vial Concentration: 0.5 (lot specific)
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 Antigen Type    Synthetic Peptide
 Clone Names    RB28937
 Antigen Source    HUMAN
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-PLEKHG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-PLEKHG3 antibody    Signal Transduction
 Applications Tested/Suitable for anti-PLEKHG3 antibody   

Western Blot (WB), ELISA (EIA), Immunohistochemistry Paraffin(IHC-P)

 Application Notes for anti-PLEKHG3 antibody    WB~~1:1000
IHC-P~~1:50~100
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 Western Blot (WB) of anti-PLEKHG3 antibody    PLEKHG3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PLEKHG3 antibody detected the PLEKHG3 protein (arrow).
anti-PLEKHG3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-PLEKHG3 antibody    PLEKHG3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLEKHG3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-PLEKHG3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for PLEKHG3. It may not necessarily be applicable to this product.
 NCBI GI #    55749621
 NCBI GeneID    26030
 NCBI Accession #    NP_056364.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_015549.1 [Other Products]
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 UniProt Primary Accession #    A1L390 [Other Products]
 UniProt Secondary Accession #    O60339; Q6GMS3; Q6P4B1; Q7L3S3; Q86SW7; Q8TEF5; Q96EW6; Q9BT82; A1L389; B5MEC9 [Other Products]
 UniProt Related Accession #    A1L390 [Other Products]
 Molecular Weight    134412
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 NCBI Official Synonym Full Names    pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 NCBI Official Symbol    PLEKHG3 [Similar Products]
 NCBI Official Synonym Symbols   
ARHGEF43; KIAA0599
[Similar Products]
 NCBI Protein Information    pleckstrin homology domain-containing family G member 3
 UniProt Protein Name    Pleckstrin homology domain-containing family G member 3
 Protein Family    Pleckstrin homology domain-containing family
 UniProt Gene Name    PLEKHG3 [Similar Products]
 UniProt Synonym Gene Names    KIAA0599; PH domain-containing family G member 3 [Similar Products]
 UniProt Entry Name    PKHG3_HUMAN
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 UniProt Comments for PLEKHG3    PLEKHG3: 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, Rac/Rho

Chromosomal Location of Human Ortholog: 14q23.3

Molecular Function: Rho guanyl-nucleotide exchange factor activity
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Product References and Citations for anti-PLEKHG3 antibody

   Olsen, J.V., et al. Cell 127(3):635-648(2006)
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 Research Articles on PLEKHG3    1. This is the first implication of chr14q23.2-23.3 in the etiology of autism and points to MTHFD1, PLEKHG3, and CHURC1 as potential candidate genes contributing to autism risk.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-PLEKHG3 antibodyOrgans/Tissues associated with anti-PLEKHG3 antibody
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >2 publications with PLEKHG3 and Mental Disorders
 Anemia Antibodies  >2 publications with PLEKHG3 and Anemia
 Neurobehavioral Manifestations Antibodies  >2 publications with PLEKHG3 and Neurobehavioral Manifestations
 Nervous System Diseases Antibodies  >2 publications with PLEKHG3 and Nervous System Diseases
 Learning Disorders Antibodies  >2 publications with PLEKHG3 and Learning Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with PLEKHG3 and Brain
 Heart Antibodies  >1 publications with PLEKHG3 and Heart
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