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anti-PLIN2 antibody :: Rabbit PLIN2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6005517
Wester Blot
Unit / Price
0.1 mg  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PLIN2, Polyclonal Antibody

★Popular Item★
 Also Known As   

PLIN2 (ADFP, Perilipin-2, Adipophilin, Adipose Differentiation-related Protein, ADRP)

 Product Synonym Names    Anti -PLIN2 (ADFP, Perilipin-2, Adipophilin, Adipose Differentiation-related Protein, ADRP)
 Product Gene Name   

anti-PLIN2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 9; NC_000009.11 (19115759..19127604, complement). Location: 9p22.1
 OMIM    103195
 3D Structure    ModBase 3D Structure for Q99541
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Monkey, Mouse, Rat
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 Specificity    Recognizes human ADFP at ~48kD. Species Crossreactivity: mouse, rat and monkey.
 Purity/Purification    Affinity Purified
Purified by affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
 Concentration    0.5 mg/ml (lot specific)
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 Immunogen    Synthetic peptide corresponding to aa426 from human ADFP.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-PLIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PLIN2 antibody

   Adipocyte differentiation-related protein (ADFP) also called Adipophilin is associated with the globule surface membrane material. ADFP (Adipophilin) occurs in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. ADFP may be a possible indicator for the identification of specialized differentiated cells containing lipid droplets and for diseases that link to fat-accumulating cells.
 Product Categories/Family for anti-PLIN2 antibody    Antibodies; Abs to Obesity Proteins
 Applications Tested/Suitable for anti-PLIN2 antibody   

Western Blot (WB)

 Application Notes for anti-PLIN2 antibody    Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-4ug/ml
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 Wester Blot of anti-PLIN2 antibody    Western Blot analysis ADFP expression with 3t3 cell lysate
anti-PLIN2 antibody Wester Blot image
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NCBI/Uniprot data below describe general gene information for PLIN2. It may not necessarily be applicable to this product.
 NCBI GI #    34577059
 NCBI GeneID    123
 NCBI Accession #    NP_001113.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001122.3 [Other Products]
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 UniProt Primary Accession #    Q99541 [Other Products]
 UniProt Secondary Accession #    Q9BSC3 [Other Products]
 UniProt Related Accession #    Q99541 [Other Products]
 Molecular Weight    48,075 Da [Similar Products]
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 NCBI Official Full Name    perilipin-2
 NCBI Official Synonym Full Names    perilipin 2
 NCBI Official Symbol    PLIN2 [Similar Products]
 NCBI Official Synonym Symbols   
ADFP; ADRP
[Similar Products]
 NCBI Protein Information    perilipin-2; adipophilin; adipose differentiation-related protein
 UniProt Protein Name    Perilipin-2
 UniProt Synonym Protein Names   
Adipophilin; Adipose differentiation-related protein
 Protein Family    Perilipin
 UniProt Gene Name    PLIN2 [Similar Products]
 UniProt Synonym Gene Names    ADFP; ADRP [Similar Products]
 UniProt Entry Name    PLIN2_HUMAN
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 NCBI Summary for PLIN2    The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
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 UniProt Comments for PLIN2    perilipin 2: May be involved in development and maintenance of adipose tissue. Belongs to the perilipin family.

Protein type: Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 9p22.1

Cellular Component: endoplasmic reticulum; plasma membrane; extracellular region; lipid particle; nucleus; cytosol

Biological Process: long-chain fatty acid transport; response to drug; sequestering of lipid; cellular lipid metabolic process; response to organic cyclic substance
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 Research Articles on PLIN2    1. Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PLIN2 antibodyPathways associated with anti-PLIN2 antibody
 Reference Product  PubMed Publications
 CARM1 antibody  >1 publications with PLIN2 and CARM1
 RXRA antibody  >1 publications with PLIN2 and RXRA
 PPARA antibody  >1 publications with PLIN2 and PPARA
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
Diseases associated with anti-PLIN2 antibodyOrgans/Tissues associated with anti-PLIN2 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >8 publications with PLIN2 and Fatty Liver
 Inflammation Antibodies  >5 publications with PLIN2 and Inflammation
 Liver Diseases Antibodies  >3 publications with PLIN2 and Liver Diseases
 Cardiovascular Diseases Antibodies  >2 publications with PLIN2 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >2 publications with PLIN2 and Kidney Diseases
 Fibrosis Antibodies  >1 publications with PLIN2 and Fibrosis
 Adenocarcinoma Antibodies  >1 publications with PLIN2 and Adenocarcinoma
 Weight Loss Antibodies  >1 publications with PLIN2 and Weight Loss
 Breast Neoplasms Antibodies  >1 publications with PLIN2 and Breast Neoplasms
 Weight Gain Antibodies  >1 publications with PLIN2 and Weight Gain
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >16 publications with PLIN2 and Muscle
 Liver Antibodies  >10 publications with PLIN2 and Liver
 Adipose Tissue Antibodies  >6 publications with PLIN2 and Adipose Tissue
 Blood Antibodies  >6 publications with PLIN2 and Blood
 Mammary Gland Antibodies  >3 publications with PLIN2 and Mammary Gland
 Bone Antibodies  >2 publications with PLIN2 and Bone
 Heart Antibodies  >2 publications with PLIN2 and Heart
 Connective Tissue Antibodies  >2 publications with PLIN2 and Connective Tissue
 Testis Antibodies  >2 publications with PLIN2 and Testis
 Kidney Antibodies  >2 publications with PLIN2 and Kidney
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