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anti-PMM1 antibody :: Rabbit anti-Human, mouse PMM1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7001010
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PMM1, Polyclonal Antibody

★Popular Item★
 Also Known As   

PMM1 Antibody

 Product Synonym Names    Phosphomannomutase 1; PMM 1; PMMH-22; PMM1; PMMH22
 Product Gene Name   

anti-PMM1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601786
 3D Structure    ModBase 3D Structure for Q92871
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, mouse
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Phosphomannomutase 1 protrin(2-262aa)
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-86200 / sc-86201
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PMM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PMM1 antibody

   Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.
 Applications Tested/Suitable for anti-PMM1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-PMM1 antibody    Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
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 Western Blot (WB) of anti-PMM1 antibody    Western blot
All lanes: PMM1 antibody at 2ug/ml
Lane 1:HepG2 whole cell lysate
Lane 2:NIH3T3 whole cell lysate
Lane 3:293T whole cell lysate
Lane 4:mouse brain tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 30kDa
Observed band size: 30kDa

anti-PMM1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-PMM1 antibody    Immunohistochemistry of paraffin-embedded human pancreas tissue using MBS7001010 at dilution 1:100
anti-PMM1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for PMM1. It may not necessarily be applicable to this product.
 NCBI GI #    194097356
 NCBI GeneID    5372
 NCBI Accession #    NP_002667.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002676.2 [Other Products]
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 UniProt Primary Accession #    Q92871 [Other Products]
 UniProt Secondary Accession #    Q92586; A8K003 [Other Products]
 UniProt Related Accession #    Q92871 [Other Products]
 Molecular Weight    29,747 Da
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 NCBI Official Full Name    phosphomannomutase 1
 NCBI Official Synonym Full Names    phosphomannomutase 1
 NCBI Official Symbol    PMM1 [Similar Products]
 NCBI Official Synonym Symbols   
Sec53
[Similar Products]
 NCBI Protein Information    phosphomannomutase 1
 UniProt Protein Name    Phosphomannomutase 1
 UniProt Synonym Protein Names   
PMMH-22
 UniProt Gene Name    PMM1 [Similar Products]
 UniProt Synonym Gene Names    PMMH22; PMM 1 [Similar Products]
 UniProt Entry Name    PMM1_HUMAN
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 NCBI Summary for PMM1    Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PMM1    PMM1: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Belongs to the eukaryotic PMM family.

Protein type: Carbohydrate Metabolism - fructose and mannose; EC 5.4.2.8; Isomerase; Carbohydrate Metabolism - amino sugar and nucleotide sugar

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: cell soma; cytosol

Molecular Function: metal ion binding; phosphomannomutase activity; protein binding

Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; GDP-mannose biosynthetic process; mannose metabolic process; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine
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 Research Articles on PMM1    1. PMM1 is responsible for the degradation of Glc-1,6-P(2) in brain
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PMM1 antibodyPathways associated with anti-PMM1 antibody
 Reference Product  PubMed Publications
 UBC antibody  >1 publications with PMM1 and UBC
 Products by Pathway  Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway antibodies  Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 GDP-mannose Biosynthesis Pathway antibodies  GDP-mannose Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
Diseases associated with anti-PMM1 antibodyOrgans/Tissues associated with anti-PMM1 antibody
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with PMM1 and Disease Models, Animal
 Liver Diseases Antibodies  >2 publications with PMM1 and Liver Diseases
 Liver Neoplasms, Experimental Antibodies  >1 publications with PMM1 and Liver Neoplasms, Experimental
 Neoplasms, Experimental Antibodies  >1 publications with PMM1 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >1 publications with PMM1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with PMM1 and Brain
 Liver Antibodies  >5 publications with PMM1 and Liver
 Pancreas Antibodies  >3 publications with PMM1 and Pancreas
 Eye Antibodies  >2 publications with PMM1 and Eye
 Embryonic Tissue Antibodies  >2 publications with PMM1 and Embryonic Tissue
 Ovary Antibodies  >1 publications with PMM1 and Ovary
 Muscle Antibodies  >1 publications with PMM1 and Muscle
 Lung Antibodies  >1 publications with PMM1 and Lung
 Heart Antibodies  >1 publications with PMM1 and Heart
 Testis Antibodies  >1 publications with PMM1 and Testis
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