NP_001186706.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,104 Da
NCBI Official Full Name
POC1 centriolar protein homolog B isoform b
NCBI Official Synonym Full Names
POC1 centriolar protein B
NCBI Protein Information
POC1 centriolar protein homolog B
UniProt Protein Name
POC1 centriolar protein homolog B
UniProt Synonym Protein Names
Pix1; Proteome of centriole protein 1B; WD repeat-containing protein 51B
UniProt Synonym Gene Names
UniProt Entry Name
POC1B_HUMAN
NCBI Summary for POC1B
POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutation in this gene result in autosomal-recessive cone-rod dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
UniProt Comments for POC1B
WDR51B: Required for ciliogenesis. Belongs to the WD repeat POC1 family.
Chromosomal Location of Human Ortholog: 12q21.33
Cellular Component: centriole; centrosome; spindle pole
Molecular Function: protein binding
Biological Process: cell proliferation; cilium biogenesis; retinal homeostasis
Disease: Cone-rod Dystrophy 20
Research Articles on POC1B
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Diseases associated with anti-POC1B antibody
Organs/Tissues associated with anti-POC1B antibody
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