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anti-POU4F3 antibody :: Rabbit anti-Human, Mouse POU4F3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7045123
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

POU4F3, Polyclonal Antibody

★Popular Item★
 Also Known As   

POU4F3 Antibody

 Product Synonym Names    POU domain; class 4; transcription factor 3; Brain-specific homeobox/POU domain protein 3C; Brain-3C; Brn-3C; POU4F3; BRN3C
 Product Gene Name   

anti-POU4F3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602459
 3D Structure    ModBase 3D Structure for Q15319
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human POU domain, class 4, transcription factor 3 protein (N-180AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-POU4F3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-POU4F3 antibody

   May play a role in determining or maintaining the identities of a small subset of visual system neurons.
 Applications Tested/Suitable for anti-POU4F3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-POU4F3 antibody    Western blot
All lanes: POU4F3antibody at 1.97ug/ml+ Mouse brain tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa

anti-POU4F3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-POU4F3 antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7045123 at dilution 1:100
anti-POU4F3 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-POU4F3 antibody    Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7045123 at dilution 1:100
anti-POU4F3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for POU4F3. It may not necessarily be applicable to this product.
 NCBI GI #    4505965
 NCBI GeneID    5459
 NCBI Accession #    NP_002691.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002700.2 [Other Products]
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 UniProt Primary Accession #    Q15319 [Other Products]
 UniProt Secondary Accession #    O60557; Q2M3F8 [Other Products]
 UniProt Related Accession #    Q15319 [Other Products]
 Molecular Weight    37,052 Da
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 NCBI Official Full Name    POU domain, class 4, transcription factor 3
 NCBI Official Synonym Full Names    POU class 4 homeobox 3
 NCBI Official Symbol    POU4F3 [Similar Products]
 NCBI Official Synonym Symbols   
BRN3C; DFNA15
[Similar Products]
 NCBI Protein Information    POU domain, class 4, transcription factor 3
 UniProt Protein Name    POU domain, class 4, transcription factor 3
 UniProt Synonym Protein Names   
Brain-specific homeobox/POU domain protein 3C; Brain-3C; Brn-3C
 Protein Family    POU domain, class 4, transcription factor
 UniProt Gene Name    POU4F3 [Similar Products]
 UniProt Synonym Gene Names    BRN3C; Brain-3C; Brn-3C [Similar Products]
 UniProt Entry Name    PO4F3_HUMAN
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 NCBI Summary for POU4F3    This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009]
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 UniProt Comments for POU4F3    POU4F3: May play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in POU4F3 are the cause of deafness autosomal dominant type 15 (DFNA15). DFNA15 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Belongs to the POU transcription factor family. Class- 4 subfamily.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: nucleoplasm

Molecular Function: transcription factor activity

Biological Process: positive regulation of transcription from RNA polymerase II promoter; visual perception

Disease: Deafness, Autosomal Dominant 15
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 Research Articles on POU4F3    1. The pou4f3 gene is regulated by ATOH1 and other transcription factors in cochlear hair cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-POU4F3 antibody
 Disease Name  Pubmed Publications
 Disease Susceptibility Antibodies  >3 publications with POU4F3 and Disease Susceptibility
 Uterine Cervical Neoplasms Antibodies  >2 publications with POU4F3 and Uterine Cervical Neoplasms
 Hyperglycemia Antibodies  >1 publications with POU4F3 and Hyperglycemia
 Leukemia Antibodies  >1 publications with POU4F3 and Leukemia
 Lung Neoplasms Antibodies  >1 publications with POU4F3 and Lung Neoplasms
 Carcinoma Antibodies  >1 publications with POU4F3 and Carcinoma
 Hyperplasia Antibodies  >1 publications with POU4F3 and Hyperplasia
 Deafness, Autosomal Dominant 15 Antibodies  >1 publications with POU4F3 and Deafness, Autosomal Dominant 15
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