NP_001275656.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 2
NCBI Official Synonym Full Names
peroxisome proliferator-activated receptor gamma, coactivator-related 1
NCBI Official Synonym Symbols
NCBI Protein Information
peroxisome proliferator-activated receptor gamma coactivator-related protein 1
UniProt Protein Name
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
UniProt Synonym Protein Names
PGC-1-related coactivator; PRC
UniProt Synonym Gene Names
NCBI Summary for PPRC1
The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
UniProt Comments for PPRC1
Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes.
Research Articles on PPRC1
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Products associated with anti-PPRC1 antibody
Pathways associated with anti-PPRC1 antibody
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