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anti-PRDX2 antibody :: Rabbit anti-Human, Mouse PRDX2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7046127
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PRDX2, Polyclonal Antibody

★Popular Item★
 Also Known As   

PRDX2 Antibody

 Product Synonym Names    Peroxiredoxin-2; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; T; PRDX2; NKEFB; TDPX1
 Product Gene Name   

anti-PRDX2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600538
 3D Structure    ModBase 3D Structure for P32119
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Peroxiredoxin-2 protein
 Conjugate    Non-conjugated
 Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23967 / sc-23970 / sc-23969 / sc-33572 / sc-33574
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PRDX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PRDX2 antibody

   Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
 Applications Tested/Suitable for anti-PRDX2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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 Western Blot (WB) of anti-PRDX2 antibody    Western blot
All lanes: PRDX2 antibody at 9ug/ml
Lane 1: Mouse liver tissue
Lane 2: Mouse spleen tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 22,16 kDa
Observed band size: 22 kDa

anti-PRDX2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-PRDX2 antibody    Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7046127 at dilution of 1:100
anti-PRDX2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-PRDX2 antibody    Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7046127 at dilution of 1:100
anti-PRDX2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-PRDX2 antibody    Immunofluorescent analysis of HepG2 cells using MBS7046127 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-PRDX2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for PRDX2. It may not necessarily be applicable to this product.
 NCBI GI #    32189392
 NCBI GeneID    7001
 NCBI Accession #    NP_005800.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005809.5 [Other Products]
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 UniProt Primary Accession #    P32119 [Other Products]
 UniProt Secondary Accession #    P31945; P32118; P35701; Q6FHG4; Q92763; Q9UC23; A8K0C0 [Other Products]
 UniProt Related Accession #    P32119 [Other Products]
 Molecular Weight    15,819 Da
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 NCBI Official Full Name    peroxiredoxin-2
 NCBI Official Synonym Full Names    peroxiredoxin 2
 NCBI Official Symbol    PRDX2 [Similar Products]
 NCBI Official Synonym Symbols   
PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a
[Similar Products]
 NCBI Protein Information    peroxiredoxin-2
 UniProt Protein Name    Peroxiredoxin-2
 UniProt Synonym Protein Names   
Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1
 Protein Family    Peroxiredoxin
 UniProt Gene Name    PRDX2 [Similar Products]
 UniProt Synonym Gene Names    NKEFB; TDPX1; NKEF-B; TSA [Similar Products]
 UniProt Entry Name    PRDX2_HUMAN
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 NCBI Summary for PRDX2    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
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 UniProt Comments for PRDX2    Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.
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 Research Articles on PRDX2    1. Oxidative stress promotes PRX2 and PRX3 hyperoxidation and attenuates pro-survival signaling in aging chondrocytes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PRDX2 antibodyPathways associated with anti-PRDX2 antibody
 Reference Product  PubMed Publications
 PRDX1 antibody  >48 publications with PRDX2 and PRDX1
 PRDX6 antibody  >19 publications with PRDX2 and PRDX6
 PRDX5 antibody  >15 publications with PRDX2 and PRDX5
 SOD1 antibody  >12 publications with PRDX2 and SOD1
 GPX4 antibody  >6 publications with PRDX2 and GPX4
 TXN antibody  >6 publications with PRDX2 and TXN
 PARK7 antibody  >1 publications with PRDX2 and PARK7
 Products by Pathway  Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 TP53 Regulates Metabolic Genes Pathway antibodies  TP53 Regulates Metabolic Genes Pathway Diagram
 Transcriptional Regulation By TP53 Pathway antibodies  Transcriptional Regulation By TP53 Pathway Diagram
Diseases associated with anti-PRDX2 antibodyOrgans/Tissues associated with anti-PRDX2 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >19 publications with PRDX2 and Carcinoma
 Inflammation Antibodies  >13 publications with PRDX2 and Inflammation
 Nervous System Diseases Antibodies  >10 publications with PRDX2 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >9 publications with PRDX2 and Cardiovascular Diseases
 Brain Diseases Antibodies  >8 publications with PRDX2 and Brain Diseases
 Liver Diseases Antibodies  >8 publications with PRDX2 and Liver Diseases
 Neoplasms, Experimental Antibodies  >7 publications with PRDX2 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >5 publications with PRDX2 and Lung Neoplasms
 Liver Neoplasms Antibodies  >5 publications with PRDX2 and Liver Neoplasms
 Necrosis Antibodies  >4 publications with PRDX2 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >62 publications with PRDX2 and Blood
 Vascular Antibodies  >19 publications with PRDX2 and Vascular
 Brain Antibodies  >19 publications with PRDX2 and Brain
 Liver Antibodies  >15 publications with PRDX2 and Liver
 Kidney Antibodies  >12 publications with PRDX2 and Kidney
 Muscle Antibodies  >10 publications with PRDX2 and Muscle
 Eye Antibodies  >9 publications with PRDX2 and Eye
 Bone Antibodies  >8 publications with PRDX2 and Bone
 Lung Antibodies  >8 publications with PRDX2 and Lung
 Heart Antibodies  >8 publications with PRDX2 and Heart
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