Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow PRDX6 rightarrow Polyclonal PRDX6  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Digoxin Antibody
 • Trefoil Factor 2 (TFF2) ELISA Kit
 • TRPM7 (CHAK1) Antibody
 • Rabies Virus Antibody
 • Clara Cell Protein 16 (CC16) ELISA Kit
 • MDA5 - Ifih1 Peptide
 • AAV5 Antibody
 • Tumor necrosis factor ligand superfamily member 14 (TNFSF14) ELISA Kit
 • Collagen alpha-2 (XI) chain (COL11A2) ELISA Kit
 • Protein Wnt-2 (WNT2) Antibody
 • Benzyl Acetoacetic Amide Biochemical
 • C type lectin domain family 4 member C (CLEC4C) ELISA Kit
 • Desmocollin-2,3 (DSC2) Antibody
 • Butyrylcholinesterase (BCHE) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PRDX6 antibody :: Rabbit PRDX6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9206852
Unit / Price
0.08 mL  /  $150 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PRDX6, Polyclonal Antibody

★Popular Item★
 Also Known As   

PRDX6 Antibody (C-term)

 Product Synonym Names    Peroxiredoxin-6; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; 311-; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase; NSGPx; Red blood cells page spot 12; PRDX6; AOP2; KIAA0106
 Product Gene Name   

anti-PRDX6 antibody

[Similar Products]
 Antibody/Peptide Pairs    PRDX6 peptide (MBS9224952) is used for blocking the activity of PRDX6 antibody (MBS9206852)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Immunogen Sequence Positions    197-224
 OMIM    602316
 3D Structure    ModBase 3D Structure for P30041
Section Bar
 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Host    Rabbit
 Species Reactivity    Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Pig, Rat)
Section Bar
 Specificity    This PRDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-224 amino acids from the C-terminal region of human PRDX6.
 Purity/Purification    Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
 Concentration    Vial Concentration: 2 (lot specific)
Section Bar
 Antigen Type    Synthetic Peptide
 Antigen Source    HUMAN
 Cellular Location    Cytoplasm. Lysosome. Cytoplasmic vesicle. Note = Also found in lung secretory organelles.
Section Bar
 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-PRDX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-PRDX6 antibody

   PRDX6is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
 Product Categories/Family for anti-PRDX6 antibody    Cancer; Cardiovascular; Cell Biology; Microbiology; Signal Transduction
 Applications Tested/Suitable for anti-PRDX6 antibody   

Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P), Flow Cytometry (FC/FACS)

 Application Notes for anti-PRDX6 antibody    WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Section Bar
 Western Blot (WB) of anti-PRDX6 antibody    Western blot analysis of PRDX6 Antibody (C-term) in CEM cell line lysates (35ug/lane). PRDX6 (arrow) was detected using the purified Pab.
anti-PRDX6 antibody Western Blot (WB) (WB) image
Section Bar
 Western Blot (WB) of anti-PRDX6 antibody    Western blot analysis of PRDX6 (arrow) using rabbit polyclonal PRDX6 Antibody (C-term) (RB20894). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRDX6 gene (Lane 2).
anti-PRDX6 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-PRDX6 antibody    Formalin-fixed and paraffin-embedded human brain tissue reacted with PRDX6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
anti-PRDX6 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Flow Cytometry (FC/FACS) of anti-PRDX6 antibody    PRDX6 Antibody (C-term) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
anti-PRDX6 antibody Flow Cytometry (FC/FACS) (FC/FACS) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PRDX6. It may not necessarily be applicable to this product.
 NCBI GI #    4758638
 NCBI GeneID    9588
 NCBI Accession #    NP_004896.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004905.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P30041 [Other Products]
 UniProt Secondary Accession #    P32077; Q5TAH4; Q5ZEZ8; A8JZY7 [Other Products]
 UniProt Related Accession #    P30041 [Other Products]
 Molecular Weight    25035
Table BarTOPTable Bar
 NCBI Official Full Name    peroxiredoxin-6
 NCBI Official Synonym Full Names    peroxiredoxin 6
 NCBI Official Symbol    PRDX6 [Similar Products]
 NCBI Official Synonym Symbols   
PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
[Similar Products]
 NCBI Protein Information    peroxiredoxin-6
 UniProt Protein Name    Peroxiredoxin-6
 UniProt Synonym Protein Names   
1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2 (EC:3.1.1.-); aiPLA2; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase (EC:1.11.1.9); NSGPx; Red blood cells page spot 12
 Protein Family    Peroxiredoxin
 UniProt Gene Name    PRDX6 [Similar Products]
 UniProt Synonym Gene Names    AOP2; KIAA0106; 1-Cys PRX; aiPLA2; NSGPx [Similar Products]
 UniProt Entry Name    PRDX6_HUMAN
Section Bar
 NCBI Summary for PRDX6    The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for PRDX6    PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily.

Protein type: EC 1.11.1.15; Amino Acid Metabolism - phenylalanine; Phospholipase; EC 1.11.1.9; Energy Metabolism - methane; Oxidoreductase

Chromosomal Location of Human Ortholog: 1q25.1

Cellular Component: extracellular space; membrane; lysosome; cytoplasmic membrane-bound vesicle; cytoplasm; cytosol

Molecular Function: antioxidant activity; phospholipase A2 activity; protein binding; peroxiredoxin activity; glutathione peroxidase activity

Biological Process: response to reactive oxygen species; hydrogen peroxide catabolic process; phospholipid catabolic process; response to oxidative stress
Table BarTOPTable Bar
 

Product References and Citations for anti-PRDX6 antibody

   Sorokina,E.M., et.al., Am. J. Physiol. Lung Cell Mol. Physiol. 297 (5), L871-L880 (2009)
Manevich,Y., et.al., Arch. Biochem. Biophys. 485 (2), 139-149 (2009)
Section Bar
 Research Articles on PRDX6    1. our findings indicate that PRDX6 promotes lung tumor growth via increased glutathione peroxidase and iPLA2 activities.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-PRDX6 antibodyPathways associated with anti-PRDX6 antibody
 Reference Product  PubMed Publications
 PRDX2 antibody  >17 publications with PRDX6 and PRDX2
 SOD1 antibody  >8 publications with PRDX6 and SOD1
 PRX antibody  >6 publications with PRDX6 and PRX
 GSTP1 antibody  >6 publications with PRDX6 and GSTP1
 GPX4 antibody  >1 publications with PRDX6 and GPX4
 NIT2 antibody  >1 publications with PRDX6 and NIT2
 Products by Pathway  Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
Diseases associated with anti-PRDX6 antibodyOrgans/Tissues associated with anti-PRDX6 antibody
 Disease Name  Pubmed Publications
 Death Antibodies  >26 publications with PRDX6 and Death
 Lung Diseases Antibodies  >18 publications with PRDX6 and Lung Diseases
 Disease Models, Animal Antibodies  >18 publications with PRDX6 and Disease Models, Animal
 Nervous System Diseases Antibodies  >17 publications with PRDX6 and Nervous System Diseases
 Inflammation Antibodies  >16 publications with PRDX6 and Inflammation
 Necrosis Antibodies  >10 publications with PRDX6 and Necrosis
 Cardiovascular Diseases Antibodies  >9 publications with PRDX6 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >8 publications with PRDX6 and Atherosclerosis
 Liver Diseases Antibodies  >8 publications with PRDX6 and Liver Diseases
 Lung Neoplasms Antibodies  >8 publications with PRDX6 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >51 publications with PRDX6 and Lung
 Blood Antibodies  >32 publications with PRDX6 and Blood
 Brain Antibodies  >31 publications with PRDX6 and Brain
 Liver Antibodies  >29 publications with PRDX6 and Liver
 Eye Antibodies  >16 publications with PRDX6 and Eye
 Vascular Antibodies  >16 publications with PRDX6 and Vascular
 Kidney Antibodies  >11 publications with PRDX6 and Kidney
 Muscle Antibodies  >10 publications with PRDX6 and Muscle
 Nerve Antibodies  >8 publications with PRDX6 and Nerve
 Skin Antibodies  >7 publications with PRDX6 and Skin
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions