NP_001231855.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,321 Da
NCBI Official Full Name
U4/U6 small nuclear ribonucleoprotein Prp4 isoform 2
NCBI Official Synonym Full Names
pre-mRNA processing factor 4
NCBI Official Synonym Symbols
PRP4; RP70; HPRP4; Prp4p; HPRP4P; SNRNP60 [Similar Products]
NCBI Protein Information
U4/U6 small nuclear ribonucleoprotein Prp4
UniProt Protein Name
U4/U6 small nuclear ribonucleoprotein Prp4
UniProt Synonym Protein Names
PRP4 homolog; hPrp4; U4/U6 snRNP 60 kDa protein; WD splicing factor Prp4
UniProt Synonym Gene Names
UniProt Entry Name
PRP4_HUMAN
NCBI Summary for PRPF4
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
UniProt Comments for PRPF4
PRPF4: Involved in pre-mRNA splicing. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Spliceosome; RNA splicing; RNA processing
Chromosomal Location of Human Ortholog: 9q31-q33
Cellular Component: Cajal body; nuclear speck; nucleoplasm; nucleus; spliceosome; U4/U6 x U5 tri-snRNP complex
Molecular Function: protein binding; U4 snRNA binding; U6 snRNA binding
Biological Process: nuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing
Disease: Retinitis Pigmentosa 70
Research Articles on PRPF4
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Products associated with anti-PRPF4 antibody
Pathways associated with anti-PRPF4 antibody
Diseases associated with anti-PRPF4 antibody
Organs/Tissues associated with anti-PRPF4 antibody
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