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anti-PRRX2 antibody :: Mouse anti-Human PRRX2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6012048 anti-PRRX2 antibody
Unit / Price
0.05 mg  /  $580 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PRRX2, Polyclonal Antibody

 Also Known As   

PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2)

 Product Synonym Names    Anti -PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2)
 Product Gene Name   

anti-PRRX2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    MDSAAAAFAL DKPALGPGPP PPPPALGPGD CAQARKNFSV SHLLDLEEVA AAGRLAARPG ARAEAREGAA REPSGGSSGS EAAPQDGECP SPGRGSAAKR KKKQRRNRTT FNSSQLQALE RVFERTHYPD AFVREELARR VNLSEARVQV WFQNRRAKFR RNERAMLASR SASLLKSYSQ EAAIEQPVAP RPTALSPDYL SWTASSPYST VPPYSPGSSG PATPGVNMAN SIASLRLKAK EFSLHHSQVP TVN
 Chromosome Location    Chromosome: 9; NC_000009.11 (132427920..132484953). Location: 9q34.1
 OMIM    604675
 3D Structure    ModBase 3D Structure for Q99811
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Recognizes human PRRX2.
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2.
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 Immunogen    Full length human PRRX2, aa1-253 (NP_057391.1).
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-PRRX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-PRRX2 antibody    Antibodies; Abs to Transcription Factors, Homeobox (HOX)
 Applications Tested/Suitable for anti-PRRX2 antibody   

Western Blot (WB)

 Application Notes for anti-PRRX2 antibody    Suitable for use in Western Blot.
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NCBI/Uniprot data below describe general gene information for PRRX2. It may not necessarily be applicable to this product.
 NCBI GI #    7706659
 NCBI GeneID    51450
 NCBI Accession #    NP_057391.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016307.3 [Other Products]
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 UniProt Primary Accession #    Q99811 [Other Products]
 UniProt Secondary Accession #    Q5SZB5; Q9UIB3 [Other Products]
 UniProt Related Accession #    Q99811 [Other Products]
 Molecular Weight    27,079 Da [Similar Products]
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 NCBI Official Full Name    paired mesoderm homeobox protein 2
 NCBI Official Synonym Full Names    paired related homeobox 2
 NCBI Official Symbol    PRRX2 [Similar Products]
 NCBI Official Synonym Symbols   
PMX2; PRX2
[Similar Products]
 NCBI Protein Information    paired mesoderm homeobox protein 2; PRX-2; paired-related homeobox protein 2; paired-like homeodomain protein PRX2
 UniProt Protein Name    Paired mesoderm homeobox protein 2
 UniProt Synonym Protein Names   
Paired-related homeobox protein 2
 Protein Family    Paired mesoderm homeobox protein
 UniProt Gene Name    PRRX2 [Similar Products]
 UniProt Synonym Gene Names    PMX2; PRX2; PRX-2 [Similar Products]
 UniProt Entry Name    PRRX2_HUMAN
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 NCBI Summary for PRRX2    The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PRRX2    PRRX2: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. Belongs to the paired homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: inner ear morphogenesis; regulation of transcription, DNA-dependent; cartilage development; positive regulation of mesenchymal cell proliferation; artery morphogenesis; positive regulation of smoothened signaling pathway; embryonic cranial skeleton morphogenesis; middle ear morphogenesis; embryonic limb morphogenesis
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 Research Articles on PRRX2    1. Model for the exceptional reactivity of peroxiredoxins 2 and 3 with hydrogen peroxide: a kinetic and computational study.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PRRX2 antibodyDiseases associated with anti-PRRX2 antibody
 Reference Product  PubMed Publications
 PAX9 antibody  >3 publications with PRRX2 and PAX9
 FGF8 antibody  >2 publications with PRRX2 and FGF8
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >3 publications with PRRX2 and Congenital Abnormalities
 Inflammation Antibodies  >2 publications with PRRX2 and Inflammation
 Brain Diseases Antibodies  >2 publications with PRRX2 and Brain Diseases
 Nervous System Diseases Antibodies  >2 publications with PRRX2 and Nervous System Diseases
 Necrosis Antibodies  >2 publications with PRRX2 and Necrosis
 Neoplasms Antibodies  >1 publications with PRRX2 and Neoplasms
 Heart Diseases Antibodies  >1 publications with PRRX2 and Heart Diseases
 Anemia Antibodies  >1 publications with PRRX2 and Anemia
 Poisoning Antibodies  >1 publications with PRRX2 and Poisoning
Organs/Tissues associated with anti-PRRX2 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >6 publications with PRRX2 and Bone
 Skin Antibodies  >5 publications with PRRX2 and Skin
 Connective Tissue Antibodies  >2 publications with PRRX2 and Connective Tissue
 Brain Antibodies  >2 publications with PRRX2 and Brain
 Eye Antibodies  >1 publications with PRRX2 and Eye
 Lung Antibodies  >1 publications with PRRX2 and Lung
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